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Fig. 6 | Chinese Medicine

Fig. 6

From: An anti-inflammatory and anti-fibrotic proprietary Chinese medicine nasal spray designated as Allergic Rhinitis Nose Drops (ARND) with potential to prevent SARS-CoV-2 coronavirus infection by targeting RBD (Delta)- angiotensin converting enzyme 2 (ACE2) binding

Fig. 6

ARND could bind to either ACE2 or Spike RBD. A ARND at different concentrations was able to bind to ACE2 receptor, and significantly competed with the Spike RBD in formation of the Spike RBD-ACE2 complex (n = 3). B ARND at different concentrations was also able to dose-dependently bind to Spike RBD. The higher the concentration of ARND, the higher was the percentage inhibition of binding (n = 3). *p < 0.05, **p < 0.01 and ***p < 0.001 vs 0 µL/mL

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