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Table 7 Adipogenesis

From: Traditional Chinese medicine promotes bone regeneration in bone tissue engineering

Active components Biomaterials Experimental model Efficacy References
Icaritin PLGA/TCP Rabbit BMSC, 3T3-L1, 10−6 M; SAON emu proximal femur defect model; SAON rabbit distal femur defect model Down-regulating C/EBP, aP2, PPAR-γ and lipid droplet [156]
PLGA/TCP BMSC, BMC 0.052: 100 (powder weight to solution volume); rat calvarial defect model Down-regulating PPAR-γ2 [145]
Gel hydrogels hMSC, 100, 200 nM; SAON rat femoral head defect Down-regulating PPAR-γ and c-Src [157]
Curcumin Silk hydrogel hBMSC; 12.5 µM Down-regulating PPAR-γ, LPL, FABp4 and Glut4 [158]
Epigallocatechin gallate PLLA ADSCs, Raw 264.7, 1 mg/mL; mouse calvarial defect Down-regulating LPL and PPAR-γ [113]