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Fig. 5 | Chinese Medicine

Fig. 5

From: Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway

Fig. 5

AC reduced liver metastasis in CC-orthotopic transplantation mice model (n = 6). A Images of liver metastasis foci in each group of model mice (blue arrows); B Number of hepatic metastasis of mice after drug administration; C–D Liver metastasis histopathological changes (H&E staining) and pathological score. tumor cell clusters (dark arrow), hepatocyte cord arrangement disorder (yellow arrow) and inflammatory cell infiltration (red arrow). E–I The content of CXCL8, IL1-β, TNF-α, IFN-γ and IL-6 in serum was detected with ELISA. p < 0.05(#), p < 0.01(##) and p < 0.001(###), compared with the sham group; p < 0.05(*), p < 0.01(**) and p < 0.001(***), compared with the model group

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