Skip to main content
Fig. 2 | Chinese Medicine

Fig. 2

From: Therapeutic material basis and underling mechanisms of Shaoyao Decoction-exerted alleviation effects of colitis based on GPX4-regulated ferroptosis in epithelial cells

Fig. 2

Effects of Shaoyao Decoction (SYD) on colonic inflammation and epithelial barrier function in colitis rats. Rats with colitis were gavaged with SYD (4 g/kg/day; 24 g/kg/day) for 7 days, then A Myeloperoxidase (MPO) activity, B colonic pro-inflammatory cytokine IL-6 and C serum fluorescein isothiocyanate-dextran (FD-4) level were measured. Transepithelial electric resistance (TEER) was measured to demonstrate the effects of SYD on barrier function in lipopolysaccharide (LPS)-induced barrier loss model in vitro (D). **P < 0.01 compared with the sham group (n = 7); ##P < 0.01 compared with 2,4,6-trinitrobenzene sulfonic acid (TNBS)/LPS control group, respectively (n = 7)

Back to article page

Chinese Medicine

ISSN: 1749-8546

Contact us