Fig. 3From: Therapeutic material basis and underling mechanisms of Shaoyao Decoction-exerted alleviation effects of colitis based on GPX4-regulated ferroptosis in epithelial cellsShaoyao Decoction (SYD) inhibited ferroptosis in colonic epithelial cells from colitis rats. A Mitochondrial morphology in colonic epithelial cells from colitis rats was determined using transmission electron microscopy (TEM); B lipid peroxidation product 4-HNE expression was measured to reflect lipid peroxidation rate. Besides, C effects of SYD-medicated serum on lipid peroxidation were also measured in Caco-2 cells pretreated with ferroptosis inducer erastin. **P < 0.01 compared with the sham group (n = 7); ##P < 0.01 compared with 2,4,6-trinitrobenzene sulfonic acid (TNBS) control group, respectively (n = 7)Back to article page