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Table 2 The topological parameters of components and key targets

From: Integrating pharmacokinetics and network analysis to investigate the mechanism of Moutan Cortex in blood-heat and blood stasis syndrome

Name

Degree

Betweenness centrality

Closeness centrality

Oxypaeoniflorin

21

0.56313

0.731707

Paeoniflorin

16

0.260056

0.588235

F7

6

0.110326

0.535714

MAPK14

5

0.093949

0.5

Gallic acid

4

0.072506

0.379747

MAPK10

4

0.059543

0.5

F2

5

0.045091

0.5

NOS3

4

0.030639

0.483871

AKT1

3

0.022278

0.405405

Methyl paraben

4

0.017795

0.4

PLAU

3

0.017271

0.46875

3,8-Dihydroxy-2-methylchromone

5

0.014472

0.38961

F10

3

0.010943

0.46875

PPARG

3

0.010943

0.46875

Quercetin

4

0.009219

0.38961

Paeonol

3

0.005351

0.379747