Fig.7

Effects of AR extracts on histopathological characterization of colon in DSS-induced mice. A Representative H&E staining images from the six different groups (× 100), red box indicates the intact crypt structure in colonic mucosa and red arrows indicated the inflammatory cells infiltration. B Representative COX-2 immunohistochemistry staining images from six different groups (× 100). C Relative quantification for the COX-2 expression (n = 5). Control (CTRL), model (DSS, 3%), high dosage of WIE (WIE-H, 3 g/kg), medium dosage of WIE (WIE-M, 1.5 g/kg), low dosage of WIE (WIE-L, 0.3 g/kg) and WAE group (WAE-H, 3 g/kg). ^### P < 0.001 vs CTRL; ^*** P < 0.001, ^* P < 0.05 vs DSS; ^& P < 0.05 vs WAE-H