Fig. 9

Effect of RGP1-1 on morphological changes and western blot analysis for examining the expressions of Nrf2, HO-1, NOQ-1, Keap-1 in cardiac tissues. A Representative images of pathological structure of heart in mice (a control blank; b model group (ISO); c inderal group; d low-dose RGP1-1; e medium-dose RGP1-1; f high-dose RGP1-1;HE staining ×400, Masson staining ×400); B, C Western blot assessments of Nrf2, HO-1, NOQ-1, Keap-1 expression in cardiac tissues. The data are presented as means ± SD (n = 10 mice per group). vs. blank control, ^##P < 0.01, ^##P < 0.05, vs. model control, ^**P < 0.01, *P < 0.05