Fig. 6

ZZDX affected the genes expression that related to the unsaturated fatty acid biosynthesis pathway. a The mRNA expression levels of Elovl4, Acot1 and Scd1 were significantly decreased after ZZDX treatment. b RT-qPCR validaton results of differentially expressed genes. c and (d) The western blot results of mouse gastric mucosa and its grayscale analysis results showed the same result with RT-qPCR. e and (f) The IHC results of mouse gastric mucosa and its staining intensity analysis also showed that after H. pylori infection, the expression levels of ELOVL4 and ACOT1 were upregulated in situ and significantly decreased after ZZDX treatment. ^#P < 0.05; ^##P < 0.01 vs. NC group; *P < 0.05; **P < 0.01; ***P < 0.001 vs. HP group