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Fig. 3 | Chinese Medicine

Fig. 3

From: Zishen Pill alleviates diabetes in Db/db mice via activation of PI3K/AKT pathway in the liver

Fig. 3

ZSP reduced obesity and improved lipid metabolism in db/db mice. a Body weight of mice over the course of treatment (n = 7). b Body mass index of mice at the end of treatment (n = 7). c Serum lipid content measured at day 28 and day 40 (n = 7). d Pictures and weights of liver and epididymal fat of mice (n = 7). e Images of H&E staining of liver and epididymal fat and oil red O staining of liver, all pictures were taken at 200 × magnification. Normal group: wt/wt mice treated with distilled water. Model group: db/db mice treated with distilled water. ZSP group: db/db mice treated with ZSP at 3.3 g/kg/day. All data presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, compared to the model group. #p < 0.05, ##p < 0.01, ###p < 0.001, compared to the normal group

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