Fig. 7From: Zishen Pill alleviates diabetes in Db/db mice via activation of PI3K/AKT pathway in the liverMechanisms underlying the anti-diabetic effects of ZSP in db/db mice livers. ZSP increases HK, PFK, GCK and GYS, decreased G6Pase. By upregulating GFs and RTKs, ZSP enhances the PI3K/AKT signal transduction in the liver, further increasing glycogen synthesis and glycolysis, and decreasing gluconeogenesis. ↑: upregulated, ↓: downregulatedBack to article page