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Fig. 3 | Chinese Medicine

Fig. 3

From: Identification of potential immunomodulators from Pulsatilla decoction that act on therapeutic targets for ulcerative colitis based on pharmacological activity, absorbed ingredients, and in-silico molecular docking

Fig. 3

The anti-inflammatory effects of BTWT in mice with DSS-induced colitis. The preventative effects of BTWT on the severity of acute colitis was demonstrated by assessing the DAI A, the colon length (B and C), and the relative colon weight to length D after the mice were sacrificed at the end of the 8 days treatment. The therapeutic effects of BTWT on the severity of chronic relapsing colitis was demonstrated by assessing the DAI (E), the colon length (F and G), and the relative colon weight to length H after mice were sacrificed at the end of the 14 days treatment. The mRNA expression of TNF-α I, IL-6 J, and IL-17 K, and the housekeeping gene GAPDH in colon tissue was determined by RT-qPCR. ## P < 0.01 and.### P < 0.001 compared with the water control group; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the DSS group (n = 5 mice per treatment group)

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Chinese Medicine

ISSN: 1749-8546

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