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Table 1 Efficacy and adverse reactions value under different rhubarb dose

From: Integrated dose–response metabolomics with therapeutic effects and adverse reactions may demystify the dosage of traditional Chinese medicine

Value

Rhubarb 1

Rhubarb 2

Rhubarb 3

Rhubarb 4

Rhubarb 5

Rhubarb 6

Moderate positive reaction (efficacy)

12.32

24.68

50.27

49.46

49.18

50.07

Excessive positive reaction

0.00

0.00

− 5.19

− 10.42

− 16.33

− 32.94

Negative reaction

− 5.44

− 6.30

− 12.81

− 9.79

− 22.35

− 19.60

Unexpected adverse reaction

− 2.14

− 5.12

− 9.85

− 10.77

− 15.48

− 17.11