Table 5 Extraction recovery and matrix effect data for the Tanreqing analytes in dog plasma (n = 6)
Analyte | Nominal concentration (ng/mL) | Extraction recovery | Matrix effect | ||
|---|---|---|---|---|---|
Mean ± SD | RSD (%) | Mean ± SD | RSD (%) | ||
Baicalin | 4 | 82.21 ± 0.07 | 8.81 | 102.15 ± 0.14 | 13.72 |
200 | 82.74 ± 0.05 | 6.45 | 93.41 ± 0.09 | 9.21 | |
Ursodeoxycholic acid | 20 | 86.42 ± 0.05 | 6.32 | 92.52 ± 0.07 | 7.82 |
1000 | 98.05 ± 0.01 | 1.34 | 99.05 ± 0.02 | 1.52 | |
Chenodeoxycholic acid | 2 | 99.09 ± 0.09 | 9.25 | 112.81 ± 0.08 | 7.50 |
100 | 99.17 ± 0.05 | 4.68 | 94.08 ± 0.03 | 3.06 | |
Chlorogenic acid | 2 | 94.62 ± 0.12 | 13.20 | 106.30 ± 0.10 | 9.35 |
100 | 90.48 ± 0.05 | 5.90 | 85.14 ± 0.03 | 3.21 | |