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Fig. 2 | Chinese Medicine

Fig. 2

From: Chaihu-Guizhi-Ganjiang Decoction is more efficacious in treating irritable bowel syndrome than Dicetel according to metabolomics analysis

Fig. 2

Differences in metabolites after treatment with Dicetel and CGGD. A Number of metabolites associated with a significantly altered treatment effect. Patients was divided into a Dicetel group (D30 vs. D0) and CGGD group (D67 vs. D37). The part of the axis that is > 0 indicates the number of metabolites whose concentration exhibits an increasing trend. The part of the axis that is < 0 indicates the number of metabolites whose concentration exhibits a decreasing trend. The ordinate expresses a simplified “super-class” of metabolites. The abscissa expresses the number of these simplified super-classes exhibiting high/low expression at different stages. These metabolites were divided into seven species according to their superclass from an Internet website (https://hmdb.ca/): “benzenoids”; “lipids and lipid-like molecules”; “organic acids and their derivatives”; “organoheterocyclic metabolites”; “organic nitrogen metabolites”; “organic oxygen metabolites”; “alkaloids and their derivatives”. B Sample distributions based on differences in efficacy-related metabolites. The positions of the different-colored spheres represent the distribution of different metabolites at different stages. PCA and PLS-DA plots using differential metabolites associated with treatment efficacy show different sample distributions in the Dicetel group and CGGD group

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