Fig. 3
Analysis of biological pathway enrichment. A Biological pathway enrichment analyses in the CGGD group and Dicetel group. The p-value was set at 0.05. The dot border color represents the significance value of pathway enrichment. “Pathway weight” is defined as the number of entities found/total number of entities. The size of the dot represents the pathway weight. “Pathway direction” is the median log2 fold change (FC) of metabolites in the pathway (red = upregulated). *p < 0.05 for D67 vs. D37 and D30 vs. D0. B Biological pathway enrichment analyses in the CGGD group and Dicetel group according to differential metabolites. The evaluation criteria were identical to those shown in Fig. 1B. The number on the Y-axis and length of the column represent the concentration of the metabolite at this stage. The X-axis represents the different stages (D0, D30, D37, and D67)