Table 1 Information about ingredients in CRD by using UPLC-Q–TOF–MS

1

1.08

Histidine

NEG

C₆H₉N₃O₂

90.0460, 80.0380, 154.0062

2

1.09

l(+)-Arginine

NEG

C₆H₁₄N₄O₂

131.0824, 41.0143

3

1.11

Aspartic acid

NEG

C₄H₇NO₄

88.0400, 41.9993, 71.0135

4

1.16

Betaine

POS

C₅H₁₁NO₂

58.0648, 118.0863

5

1.2

Trigonelline

POS

C₇H₇NO₂

92.0485, 138.0548, 78.0337

6

1.24

Quinic acid

NEG

C₇H₁₂O₆

191.0560, 85.0296, 93.0347

7

1.24

Proline

POS

C₅H₉NO₂

70.0651, 116.0705

8

1.5

Shikimic acid

NEG

C₇H₁₀O₅

93.0347, 85.0299, 111.0091

9

1.57

Adenine

POS

C₅H₅N₅

119.0353, 136.0617, 92.0242

10

1.64

Cytidine

NEG

C₉H₁₃N₃O₅

109.0406, 81.0450, 41.9983

11

1.74

Nicotinic acid

POS

C₆H₅NO₂

124.0391, 78.0337, 80.0409

12

1.92

Nicotinamide

POS

C₆H₆N₂O

80.0493, 123.0548, 53.0385

13

1.93

Citric acid

NEG

C₆H₈O₇

111.0089, 87.0087, 85.0296

14

2.1

Vitamin B6

POS

C₈H₁₁NO₃

134.0602, 152.0707, 94.0649

15

2.38

Amber acid

NEG

C₄H₆O₄

73.0299, 99.9261, 117.0200

16

2.54

Adenosine

NEG

C₁₀H₁₃N₅O₄

134.0467, 107.0238

17

2.64

Guanosine

NEG

C₁₀H₁₃N₅O₅

150.0425, 133.0157, 108.0204

18

2.78

Gallic acid

NEG

C₇H₆O₅

125.0246, 79.0188, 169.0155

19

3.01

Gastrodin

NEG

C₁₃H₁₈O₇

123.0447, 105.0368, 77.0393

20

3.38

Phenprobamate

NEG

C₉H₁₁NO₂

103.0553, 72.0094

21

3.38

Phenylalanine

POS

C₉H₁₁NO₂

120.0804, 103.0543, 77.0386

22

4.02

Protocatechuic acid

NEG

C₇H₆O₄

109.0298, 153.0186

23

4.15

Hydroxytyrosol

NEG

C₈H₁₀O₃

123.0453, 153.0512

24

4.5

l-Tryptophan

NEG

C₁₁H₁₂N₂O₂

116.0508, 203.0818, 74.0251

25

4.53

Higenamine

NEG

C₁₆H₁₇NO₃

162.0557, 160.0442

26

5.03

Protocatechuic aldehyde

NEG

C₇H₆O₃

136.0160, 108.0218, 92.0280

27

5.08

Vitexin

NEG

C₂₁H₂₀O₁₀

311.0563, 431.0984, 283.0612

28

5.18

Vaccarin

POS

C₃₂H₃₈O₁₉

595.1675, 727.2072, 313.0713

29

5.19

Chlorogenic acid

NEG

C₁₆H₁₈O₉

191.0558, 127.0410

30

5.24

Catechin

NEG

C₁₅H₁₄O₆

109.0297, 123.0458, 289.0758

31

5.41

p-Coumaric acid

NEG

C₉H₈O₃

119.0509, 93.0378

32

5.62

Secoisolariciresinol diglucoside

POS

C₃₂H₄₆O₁₆.NH₃

327.1579.137.0582

33

5.7

Esculetin

NEG

C₉H₆O₄

89.0290, 41.0029, 188.0178

34

5.8

Puerarin

NEG

C₂₁H₂₀O₉

267.0683, 295.0620, 415.1036

35

6.07

Vitamin B2

POS

C₁₇H₂₀N₄O₆

243.0872, 377.1438

36

6.41

Pinoresinol diglucoside

NEG

C₃₂H₄₂O₁₆.HCOOH

357.1349, 519.1865

37

6.63

Daidzin

NEG

C₂₁H₂₀O₉.HCOOH

295.0620, 415.1036, 267.0683

38

6.83

Eleutheroside E

NEG

C₃₄H₄₆O₁₈.HCOOH

417.1547, 529.2046

39

6.99

Mulberroside A

NEG

C₂₆H₃₂O₁₄

243.0662, 567.1756

40

7.1

Typhaneoside

NEG

C₃₄H₄₂O₂₀

769.2190, 314.0435

41

7.3

Rutin

NEG

C₂₇H₃₀O₁₆

609.1461, 300.0276, 271.0244

42

7.41

Syringaldehyde

POS

C₉H₁₀O₄

95.0491, 77.0382, 140.0468

43

7.44

p-Anisic acid

NEG

C₈H₈O₃

107.0498, 92.0273

44

7.46

Daphnetin

POS

C₉H₆O₄

133.0283, 89.0388, 77.0392

45

7.49

Liquiritigenin

POS

C₁₅H₁₂O₄

137.0234, 147.0438, 257.0798

46

7.59

Scopoletin

POS

C₁₀H₈O₄

133.0283, 178.0246, 193.0494

47

7.6

Hyperin

NEG

C₂₁H₂₀O₁₂

300.0275, 463.0875, 271.0251

48

7.61

Isoquercitrin

POS

C₂₁H₂₀O₁₂

303.0501

49

7.62

Quercetin

POS

C₁₅H₁₀O₇

303.0497, 137.0604

50

7.64

2, 3, 5, 4′-Tetrahydroxystilbene-2-O-b-d-glucoside

NEG

C₂₀H₂₂O₉

243.0679, 137.0245, 173.0607

51

7.66

Ferulic acid

NEG

C₁₀H₁₀O₄

134.0371, 178.0275, 193.0507

52

7.86

6-Hydroxy-7, 8-dimethoxycoumarin

POS

C₁₁H₁₀O₅

223.0610, 190.0259, 162.0307

53

7.86

Isofraxidin

POS

C₁₁H₁₀O₅

223.0610, 162.0307, 107.0493

54

7.94

Ginkgolide B

NEG

C₂₀H₂₄O₁₀.HCOOH

125.0241, 367.1396, 423.1260

55

7.96

Aempferol-3-O-rutinoside

NEG

C₂₇H₃₀O₁₅

285.0402, 593.1514

56

8

Bilobalide

NEG

C₁₅H₁₈O₈

163.1128, 193.1235

57

8.09

Ginkgolide C

NEG

C₂₀H₂₄O₁₁

125.0245, 383.1359, 113.0248

58

8.11

Isorhamnetin-3-O-neohespeidoside

POS

C₂₈H₃₂O₁₆

317.0646

59

8.12

Isorhamnetin

POS

C₁₆H₁₂O₇

317.0664, 302.0421, 153.0179

60

8.23

1,5-Dicaffeoylquinic acid

NEG

C₂₅H₂₄O₁₂

191.0559, 353.0877

61

8.27

Calycosin

NEG

C₁₆H₁₂O₅

268.0371, 283.0604, 211.0397

62

8.3

Astragalin

NEG

C₂₁H₂₀O₁₁

284.0328, 447.0932, 255.0300

63

8.31

Pinoresinol-glucoside

NEG

C₂₆H₃₂O₁₁

151.0400, 357.1343

64

8.61

3-Hydroxymorindone

POS

C₁₅H₁₀O₆

287.0552, 153.0179

65

8.61

Kaempferol

POS

C₁₅H₁₀O₆

287.0552, 213.0537

66

9.63

Ginsenoside Rg1

NEG

C₄₂H₇₂O₁₄.HCOOH

799.4828, 637.4311, 161.0450

67

9.83

Ononin

NEG

C₂₂H₂₂O₉.HCOOH

267.0654, 252.0422

68

10.03

Daidzein

NEG

C₁₅H₁₀O₄

253.0506, 208.0533, 224.0478

69

10.04

Astragaloside I

NEG

C₄₅H₇₂O₁₆.HCOOH

913.4798, 914.4838

70

10.44

Ginkgolide A

POS

C₂₀H₂₄O₉

345.1328, 281.1172

71

10.88

Formononetin

NEG

C₁₆H₁₂O₄

252.0429, 223.0405, 195.0449

72

11.22

Pectolinarigenin

NEG

C₁₇H₁₄O₆

283.0249, 227.0351, 298.0477

73

11.83

Naringenin

NEG

C₁₅H₁₂O₅

119.0501, 151.0034, 271.0592

74

12.17

Pseuoginsenoside F11

NEG

C₄₂H₇₂O₁₄

799.4858, 637.4295

75

12.39

Gypenoside XVII

POS

C₄₈H₈₂O₁₈

325.1132, 163.0602, 407.3671

76

12.66

Hydroxygenkwanin

NEG

C₁₆H₁₂O₆

255.0299, 284.0319, 299.0531

77

12.9

Ginsenoside Rg2

NEG

C₄₂H₇₂O₁₃.HCOOH

783.4910, 101.0246

78

12.99

Ginsenoside-Ro

NEG

C₄₈H₇₆O₁₉

955.4885

79

12.99

Ursolic acid

POS

C₃₀H₄₈O₃

411.3602, 439.3555

80

13.02

Ginsenoside Rh1

NEG

C₃₆H₆₂O₉.HCOOH

683.4394, 637.4381, 475.3804

81

13.24

Amentoflavone

NEG

C₃₀H₁₈O₁₀

537.0828, 375.0496, 417.0616

82

14.28

Parthenolide

POS

C₁₅H₂₀O₃

119.0856, 145.1012

83

15.64

Saikosaponin C

NEG

C₄₈H₇₈O₁₇

925.5156

84

15.82

Neobavaisoflavone

NEG

C₂₀H₁₈O₄

321.1128, 265.0505, 305.0809

85

16.24

3-N-Butyl-4,5-dihydrophthalide

POS

C₁₂H₁₆O₂

91.0537, 77.0380, 137.0593

86

16.43

Raddeanin A

NEG

C₄₇H₇₆O₁₆

895.5055

87

16.86

Panaxydol

POS

C₁₇H₂₄O₂

77.0385, 105.0334

88

17.32

Emodin

NEG

C₁₅H₁₀O₅

269.0462, 225.0562, 241.0513

89

17.45

Ligustilide

POS

C₁₂H₁₄O₂

91.0543, 79.0538, 191.1058

90

17.75

Costunolide

POS

C₁₅H₂₀O₂

177.0907, 91.0538

91

17.76

Pregnenolone

POS

C₂₁H₃₂O₂

159.1179, 281.2262, 317.2456

92

18.3

Gingerglycolipid B

NEG

C₃₃H₅₈O₁₄.HCOOH

397.1360, 677.3745, 279.2328

93

19.26

Reserpine

POS

C₃₃H₄₀N₂O₉

609.2808, 397.2138, 195.0642

94

19.33

Patchouli alcohol

POS

C₁₅H₂₄

93.0697, 121.1008

95

19.63

Levistilide A

POS

C₂₄H₂₈O₄

191.1065, 149.0598