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Table 1 Lists of structures including studied molecules and corresponding experimental activity
figure a

From: Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors

Compd

R1

R2

R3

R4

pIC50

1

rha

glu

CH3

 

5.082

2

rha- (1–2) rha

H

CH3

 

5.490

3

rha

H

CH3

 

5.262

4t

rha- (1–2) glu

glu

CH3

 

3.389

5

rha- (1–2) xyl

glu

CH3

 

3.447

6

rha- (1–2) rha

glu

CH3

 

3.166

7

H

H

CH3

 

5.658

8

rha

CH2CH2OH

CH3

 

6.444

9

CH2CH2OH

CH2CH2OH

CH3

 

7.131

10t

H

OCH3

  

5.745

11

H

H

  

5.222

12t

H

OCH3

OCH3

OCH2Phe

5.229

13

H

H

H

OCH3

5.155

14

H

   

5.208

15

H

CH3

  

4.342

16

H

   

7.847

17

H

H

  

6.222

  1. t test set compounds
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