From: Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors
Compd
PDE5A1 (IC50 ± SD) (μM)
1
8.27 ± 0.74
2
3.23 ± 0.23
3
5.47 ± 0.56
4
408.60 ± 31.4
5
357.60 ± 34.2
6
681.90 ± 38.4
Sildenafil
0.0142 ± 0.0013