Fig. 1

Evaluation of the therapeutic effect of ADI on the pancreatic cancer xenograft mice. A Subcutaneous tumors were observed in mice from four groups. B Growth curves of tumor volume in mice from four groups. C Tumor weight in mice from four groups. D HE staining for tumor tissues in mice from four groups. The right diagram (20 ×) is the local amplification of the left one (10 ×). ADI-L, Low-dose ADI-treated mice group; ADI-M, Medium-dose ADI-treated group; ADI-H, High-dose ADI-treated mice group. ^**p < 0.01, ^***p < 0.001 compared with Control group