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Table 2 VIP value and correlation coefficient of the severity of AEs (in different age stage)

From: Variable importance for projection (VIP) scores for analyzing the contribution of risk factors in severe adverse events to Xiyanping injection

  

XYP

RB

CTR

PS

AH

DA

FOX

AZM

CAZ

AMC

LEVH

CSP

ACY

0–6 years old

VIP index

3.124

1.158

0.194

0.274

0.170

0.788

0.278

0.369

0.818

0.355

0.185

0.245

0.194

Coeff

− 0.043

0.010

− 0.005

− 0.006

− 0.001

0.007

− 0.006

− 0.002

0.006

0.001

− 0.003

− 0.005

− 0.004

7–17 years old

VIP index

1.329

1.360

0.915

0.550

0.559

0.778

1.502

0.751

0.711

Coeff

− 0.025

0.012

− 0.002

− 0.009

− 0.004

− 0.012

− 0.025

0.002

− 0.011

18–40 years old

VIP index

1.857

1.147

0.939

0.939

0.570

0.044

0.380

Coeff

− 0.041

0.025

0.021

0.021

0.007

− 0.006

− 0.002

41–65 years old

VIP index

2.169

0.414

0.914

0.611

0.591

0.979

0.650

0.431

Coeff

− 0.067

0.008

0.026

0.012

0.012

0.029

0.020

0.000

 > 65 years old

VIP index

2.400

0.606

0.169

1.232

0.267

0.441

0.240

0.050

 

Coeff

− 0.092

0.009

− 0.015

0.037

− 0.018

0.001

− 0.021

− 0.020

  1. The green flag indicates that the correlation coefficient is < 0, and that this factor had a negative impact on the severity of the AE and tended to result in general AEs. The red flag indicates that the correlation coefficient > 0, and this factor had an active impact on the severity of the AE and tended to result in a severe AE. The VIP value is 0 or the drug is not used, which is not shown