Fig. 6

KXS up-regulated the expression of SIRT3 proteins and down-regulated the expression of neurotrophic NLRP3 inflammasome-related proteins in the hippocampus of APP/PS1 mice. A Expression of SIRT3 and NLRP3 inflammasome-related proteins; B Histogram of relative expression of SIRT3 proteins; C–G Histogram of relative expression of NLRP3 inflammasome-related proteins; H Representative immunofluorescent imaging of SIRT3 (red) and DPAI (blue); I Representative immunofluorescent imaging of NLRP3 (red) and DPAI (blue). KXS-H: 10 g/kg/day. The experiment data are expressed as means ± SEM. n = 3 in each group. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. Ctrl group; *P < 0.05, **P < 0.01, ***P < 0.001 vs. APP/PS1 group