Skip to main content

Table 2 Chinese herbal formulas

From: Potential traditional Chinese medicines with anti-inflammation in the prevention of heart failure following myocardial infarction

Name

Composition

In clinic

In experiments

Targets or pathway

Cardiac function

Reference

  

Application

inflammation

Model

Inflammation

   

Gualou Xiebai Decoction

Scallion, Gualouzi

AMI

TGF-β, TNF-α and IL-1↓

LAD in MI rats

NF-κB↓

IVS, LVPW, EF and FS↑

[127,128,129]

Sini Tang

Aconite, Licorice, Dried Ginger

MI; CAD; CHF

LAD in MI rats

IL-6, IL-1β and TNF-α↓

NO↑

EF↑

[130,131,132]

Qishenyiqi Pill

Salvia Miltiorrhiza, Panax Notoginseng Huang Astragalus, And Dalbergia

HF

LAD in MI rats

TNF-α, IL-6, IL-1β↓

LOX↓, NO↑;NF-κB and IL-6-STAT3↓

cTnI↓TLVSP and Max dP/dt↑, LVEDP and Min dP/dt↓

[134,135,136,137]

Danhong Injection

Danshen And Honghua

AMI

LAD in HF rats

IL-6, IL-1β, TNF-α↓

NF-κB and IκB-α↓

LVEF, LVFS and + dp/dtmax↑ -dp/dtmax↓

[139, 140]

Guan Maitong

Astragalus, Pueraria Salvia Miltiorrhiza, Safflower And Polygonum Multiflorum

CAD

LAD in MI rats

IL-1, TNF-α

ICAM-1↓

CK,CK-MB and LDH↓

[142]

Qiliqiangxin

Ginseng Radix Et Rhizoma, Astragali Radix, Aconiti Lateralis Radix Preparata, and et al

CHF

LAD in MI rats

TNF-α and IL-6↓; TNF-α/IL-10↓

NF-κB and p-IκBα↓

EF and FS↑, LVEDd↓

[145,146,147,148]

Shenfu Injection

Ginseng And Aconite

AMI

LAD in HF rats

PTX3↓

LVSP, + dp/dtmax and -dp/dtmax↑; LVEDP↓

[149,150,151]

Shexiang Baoxin Pills

Musk, Ginseng Root, Cow Bezoar, Cinnamon, Cassia Bark, Toad Venom, And Borneol

Angina pectoris

LAD in MI rats

IL-6, TNF-α↓

LVESP and LV ± dp/dtmax

[153, 154]

Fufang Danshen Dripping Pill

Danshen, Panax Notoginseng And Borneol

CAD and HF

CRP,IL-6 and TNF-α↓

LAD in AMI rabbits

TNF-α↓

[160, 161]