Name | Composition | In clinic | In experiments | Targets or pathway | Cardiac function | Reference | ||
---|---|---|---|---|---|---|---|---|
Application | inflammation | Model | Inflammation | |||||
Gualou Xiebai Decoction | Scallion, Gualouzi | AMI | TGF-β, TNF-α and IL-1↓ | LAD in MI rats | ∕ | NF-κB↓ | IVS, LVPW, EF and FS↑ | |
Sini Tang | Aconite, Licorice, Dried Ginger | MI; CAD; CHF | – | LAD in MI rats | IL-6, IL-1β and TNF-α↓ | NO↑ | EF↑ | |
Qishenyiqi Pill | Salvia Miltiorrhiza, Panax Notoginseng Huang Astragalus, And Dalbergia | HF | – | LAD in MI rats | TNF-α, IL-6, IL-1β↓ | LOX↓, NO↑;NF-κB and IL-6-STAT3↓ | cTnI↓TLVSP and Max dP/dt↑, LVEDP and Min dP/dt↓ | |
Danhong Injection | Danshen And Honghua | AMI | – | LAD in HF rats | IL-6, IL-1β, TNF-α↓ | NF-κB and IκB-α↓ | LVEF, LVFS and + dp/dtmax↑ -dp/dtmax↓ | |
Guan Maitong | Astragalus, Pueraria Salvia Miltiorrhiza, Safflower And Polygonum Multiflorum | CAD | – | LAD in MI rats | IL-1, TNF-α | ICAM-1↓ | CK,CK-MB and LDH↓ | [142] |
Qiliqiangxin | Ginseng Radix Et Rhizoma, Astragali Radix, Aconiti Lateralis Radix Preparata, and et al | CHF | – | LAD in MI rats | TNF-α and IL-6↓; TNF-α/IL-10↓ | NF-κB and p-IκBα↓ | EF and FS↑, LVEDd↓ | |
Shenfu Injection | Ginseng And Aconite | AMI | – | LAD in HF rats | – | PTX3↓ | LVSP, + dp/dtmax and -dp/dtmax↑; LVEDP↓ | |
Shexiang Baoxin Pills | Musk, Ginseng Root, Cow Bezoar, Cinnamon, Cassia Bark, Toad Venom, And Borneol | Angina pectoris | – | LAD in MI rats | IL-6, TNF-α↓ | – | LVESP and LV ± dp/dtmax↑ | |
Fufang Danshen Dripping Pill | Danshen, Panax Notoginseng And Borneol | CAD and HF | CRP,IL-6 and TNF-α↓ | LAD in AMI rabbits | TNF-α↓ | – | – |