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Table 4 Ongoing clinical trials of TCM in treatment and precaution of irAEs

From: Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions

Year-author

Registry number

Study type

IrAE

TCM

Formulation

Intervention

Controlled

Sample size

Primary outcomes

2022-Ma X

ChiCTR2200059759

Cohort study

NA

Electroacupuncture

Acupuncture

Electroacupuncture stimulation of Zusanli acupoint

Without any acupuncture/Sham acupuncture stimulation of Zusanli acupoint

100/100/100

OS

2022-Shu Q

ChiCTR2200059263

RCT

Skin

Pi-Yan-Ning

Compound prescription

Pi-Yan-Ning

Corticosteroide

25/25

Median time of disease remission and drug efficacy

  1. IrAE immune checkpoint inhibitors-related adverse event, TCM traditional Chinses medicine, NA not available, OS overall survival, RCT randomized controlled trial