Fig. 3

Protein identification and potential targets of GHSPT in treating PF. A Proteomics analysis of 19 back-regulated proteins after GHSPT therapy in the lung tissue of PF mice. Volcano plot indicating significantly altered proteins identified in the combined datasets, B between PF group and CC group; C between GH group and PF group. Cluster heatmap indicating significantly altered proteins identified in the combined datasets, D between PF group and CC group; E between GH group and PF group. F A total of 821 and 328 targets of PF and potential active ingredients (GHSPT), respectively, and they shared 92 overlapping targets. G A total of 821 and 178 targets of PF and serum migrant compounds (GHSPT), respectively, and they shared 33 overlapping targets. CC control group, PF bleomycin-induced PF group, GH GHSPT treated bleomycin-induced PF group, GH1 potential active ingredients of GHSPT, GH2 serum migrant compounds of GHSPT, GHSPT ginseng honeysuckle superfine powdered tea, PF pulmonary fibrosis