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  1. In traditional Chinese medicine (TCM) clinical practice, TCM syndromes help to understand human homeostasis and guide individualized treatment. However, the TCM syndrome changes with disease progression, of wh...

    Authors: Yiyu Lu, Zhaoyuan Fang, Tao Zeng, Meiyi Li, Qilong Chen, Hui Zhang, Qianmei Zhou, Yiyang Hu, Luonan Chen and Shibing Su

    Citation: Chinese Medicine 2019 14:52

    Content type: Research

    Published on:

  2. Ginkgo biloba is a medicinal plant which contains abundant endophytes and various secondary metabolites. According to the literary about the information of endophytics from Ginkgo biloba, Chaetomium, Aspergillus,...

    Authors: Zhihui Yuan, Yun Tian, Fulin He and Haiyan Zhou

    Citation: Chinese Medicine 2019 14:51

    Content type: Review

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  3. Allergic rhinitis (AR) is a common disease. No evidence is available for the clinical application of acupuncture and moxibustion for the management of AR symptoms in Hong Kong. This study aimed to evaluate the...

    Authors: Ting Yiu Yung, Hongwei Zhang, Lap Che Tang, Lang Zhang, Chak On Law, Wai Man Tam, Chun Wai Chan, Heng Chun Chen, Man Hork Lee, Tat Chi Ziea, Fung Leung Ng and Zhi Xiu Lin

    Citation: Chinese Medicine 2019 14:50

    Content type: Research

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  4. Lycium barbarum (wolfberry) has been widely cultivated in China, particularly in northwest regions. However, the fruit size and taste of L. barbarum from different habitats are quite different. Traditionally, onl...

    Authors: Ying Wang, Hongyu Jin, Xiaoxv Dong, Shuang Yang, Shuangcheng Ma and Jian Ni

    Citation: Chinese Medicine 2019 14:49

    Content type: Research

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  5. Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects, as well as regulate auto...

    Authors: Hua Luo, Chi Teng Vong, Hanbin Chen, Yan Gao, Peng Lyu, Ling Qiu, Mingming Zhao, Qiao Liu, Zehua Cheng, Jian Zou, Peifen Yao, Caifang Gao, Jinchao Wei, Carolina Oi Lam Ung, Shengpeng Wang, Zhangfeng Zhong…

    Citation: Chinese Medicine 2019 14:48

    Content type: Review

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  6. Herbal materials are widely used as medicinal products, dietary supplements, food, and spices. With increased consumption, the safety, quality, and efficacy of herbal materials are becoming more relevant. The ...

    Authors: Mengmeng Sun, Shengpeng Wang, Yong Jing, Li Li, Min He, Yusheng Jia, Eduard van Wijk, Yitao Wang, Zhihong Wang and Mei Wang

    Citation: Chinese Medicine 2019 14:47

    Content type: Research

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  7. The side effects caused by Polygoni Multiflori Radix (PMR) and Polygoni Multiflori Radix Praeparata (PMRP) have often appeared globally. There is no research on the changes of endogenous metabolites among PMR-...

    Authors: Zhaoyan Zhang, Liang Yang, Xiaoyan Huang and Yue Gao

    Citation: Chinese Medicine 2019 14:46

    Content type: Research

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  8. Magnolia officinalis Rehd. et Wils, commonly called Houpo, has been used for thousands of years in China as a traditional herbal medicine. The primary processing of Houpo requires sweating treatment, which is a s...

    Authors: Qinahua Wu, Dan Wei, Linlin Dong, Yuping Liu, Chaoxiang Ren, Qianqian Liu, Cuiping Chen, Jiang Chen and Jin Pei

    Citation: Chinese Medicine 2019 14:45

    Content type: Research

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  9. Gastric mucosal lesion (GML) is the initiating pathological process in many refractory gastric diseases. And moxibustion is an increasingly popular alternative therapy that prevents and treats diseases. Howeve...

    Authors: Yuan Zhang, Miao-sen Huang, Cai-chun Liu, Lin-yu Lian, Jia-cheng Shen, Qi-da He, Ying-jie Wang, Long-bin Zhang, Mi Liu and Zong-bao Yang

    Citation: Chinese Medicine 2019 14:44

    Content type: Research

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  10. Trichosanthis semen, the seeds of Trichosanthes kirilowii Maxim. or Trichosanthes rosthornii Harms, has long been used in Korean medicine to loosen bowels and relieve chronic constipation. Although the fruits and...

    Authors: Su Mi Park, Sang Kyu Jeon, Ok Hyeon Kim, Jung Yun Ahn, Chang-Hyun Kim, Sun-Dong Park and Ju-Hee Lee

    Citation: Chinese Medicine 2019 14:43

    Content type: Research

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  11. The dry root and rhizome of Salvia miltiorrhiza Bunge, or Danshen, is a well-known, traditional Chinese medicine. Tanshinones are active compounds that accumulate in the periderm, resulting in red-colored roots. ...

    Authors: Zhilai Zhan, Wentao Fang, Xiaohui Ma, Tong Chen, Guanghong Cui, Ying Ma, Liping Kang, Tiegui Nan, Huixin Lin, Jinfu Tang, Yan Zhang, Changjiangsheng Lai, Zhenli Ren, Yanan Wang, Yujun Zhao, Ye Shen…

    Citation: Chinese Medicine 2019 14:42

    Content type: Research

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  12. Pheretima is a minister drug in Naoxintong capsule (NXTC), a well-known traditional Chinese medicine (TCM) formula for the treatment of cardiovascular and cerebrovascular diseases. Owing to the loss of morphol...

    Authors: Xiaoxiao Zhu, Hoi-Yan Wu, Pang-Chui Shaw, Wei Peng and Weiwei Su

    Citation: Chinese Medicine 2019 14:41

    Content type: Research

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  13. Polysaccharides in carob fruit, including carob bean gum (also known as carob gum, locust bean gum) and carob fiber, are widely used in industries such as food, pharmaceuticals, paper, textile, oil well drilli...

    Authors: Bao-Jie Zhu, Mohamed Zaky Zayed, Hua-Xu Zhu, Jing Zhao and Shao-Ping Li

    Citation: Chinese Medicine 2019 14:40

    Content type: Review

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  14. To investigate the effects and immunological mechanisms of the traditional Chinese medicine Xinjiaxiangruyin on controlling influenza virus (FM1 strain) infection in mice housed in a hygrothermal environment.

    Authors: Ying-Jie Fu, Yu-Qi Yan, Xiao Zheng, Shan-Shan Shi, Sha Wu and Zhen-You Jiang

    Citation: Chinese Medicine 2019 14:39

    Content type: Research

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  15. Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines. However, the variation of Chinese me...

    Authors: Jingjing Pan, Siyuan He, Jiayao Zheng, Jingyuan Shao, Ning Li, Yunqi Gong and Xingchu Gong

    Citation: Chinese Medicine 2019 14:38

    Content type: Research

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  16. Modern pharmacological studies have demonstrated that Baihe–Zhimu decoction (BZD) has antidepressant effects. However, the complex composition and lack of clear evaluation standards for BZD make it less likely...

    Authors: Ming Zhong, Xiaoting Tian, Shuoji Chen, Mingcang Chen, Ziqiong Guo, Minna Zhang, Gongpu Zheng, Zhixiong Li, Zhangpeng Shi, Guanghui Wang, Honggang Gao, Fang Liu and Chenggang Huang

    Citation: Chinese Medicine 2019 14:37

    Content type: Research

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  17. Shunxinzufang decoction is tutors, empirical formula and has been used in Chinese patients of HFpEF for several years. The aim of this study was to make into sustained release granules and select the best form...

    Authors: Yinghuan Dou, Xuefeng Li, Yanbin Shi, Jiaying Zhang, Yang Yuan, Mengru Zhou, Xiangxiang Wei and Xiaoying Zhang

    Citation: Chinese Medicine 2019 14:36

    Content type: Research

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  18. Sigesbeckia glabrescens Makino (SG) is one of the important plant origins of Sigesbeckiae herba and has been widely used for the treatment of chronic inflammatory diseases in China. However, the underlying anti-i...

    Authors: Zhangfeng Zhong, Qianru Zhang, Hongxun Tao, Wei Sang, Liao Cui, Wenan Qiang, Wai San Cheang, Yuanjia Hu, Hua Yu and Yitao Wang

    Citation: Chinese Medicine 2019 14:35

    Content type: Research

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  19. Periplaneta americana L. is a Traditional Chinese Medicine that has been used in clinic treatment of various diseases for a long history. However, the therapeutic potential and the underlying mechanism of Peripla...

    Authors: Long-Jian Li, Mao-Ze Wang, Tie-Jun Yuan, Xue-Han Xu, Haseeb Anwar Dad, Chui-Liang Yu, Jian Hou and Li-Hua Peng

    Citation: Chinese Medicine 2019 14:33

    Content type: Research

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  20. Acupoint catgut embedding therapy characterized by acupoint, needle and catgut are superior to traditional acupuncture, due to exerting more comprehensive therapeutic efficacy. However, it is still deficient i...

    Authors: Li-Shu Chen, Yue-Ying Li, Hao Chen, Bo-Wen Liu, Da-Wei Wang and Yong-Hua Zhao

    Citation: Chinese Medicine 2019 14:32

    Content type: Research

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  21. In China, the medical use of fecal matter (fresh fecal suspension or dry feces) can be dated back to the fourth century, approximately 1700 years ago. In long-term clinical practice, Chinese doctors have accum...

    Authors: Huan Du, Ting-ting Kuang, Shuang Qiu, Tong Xu, Chen-Lei Gang Huan, Gang Fan and Yi Zhang

    Citation: Chinese Medicine 2019 14:31

    Content type: Review

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  22. Astragali Radix (AR) is widely-used for improving liver fibrosis, but, the mechanism of action has not been systematically explained. This study aims to investigate the mechanism of AR intervention in liver fibro...

    Authors: Dan Wang, Ruisheng Li, Shizhang Wei, Sijia Gao, Zhuo Xu, Honghong Liu, Ruilin Wang, Haotian Li, Huadan Cai, Jian Wang and Yanling Zhao

    Citation: Chinese Medicine 2019 14:30

    Content type: Research

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  23. Guzhi Zengsheng Zhitongwan (GZZSZTW) is an effective formula of traditional Chinese herbal medicine and has been widely applied in the treatment of joint diseases for many years. The aim of this study was to d...

    Authors: Baojin Yao, Jia Liu, Duoduo Xu, Daian Pan, Mei Zhang, Daqing Zhao and Xiangyang Leng

    Citation: Chinese Medicine 2019 14:29

    Content type: Research

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  24. Cyclocarya paliurus (Batal.) Ijinskaja (CP) is a monotypic genus plant, also called sweet tea tree that belongs to the Juglandaceae family, which is mainly distributed in the subtropical highlands in China. Our p...

    Authors: Zi-Wan Ning, Li-xiang Zhai, Jiao Peng, Ling Zhao, Tao Huang, Cheng-yuan Lin, Wei-hong Chen, Zhen Luo, Hai-tao Xiao and Zhao-xiang Bian

    Citation: Chinese Medicine 2019 14:28

    Content type: Research

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  25. Radix Salviae Miltiorrhizae (RSM), a well-known traditional Chinese medicine, has been shown to inhibit tumorigenesis in various human cancers. However, the anticancer effects of RSM on human hepatocellular carci...

    Authors: Yi Luo, Yu Feng, Lei Song, Gan-Qing He, Sha Li, Sha-Sha Bai, Yu-Jie Huang, Si-Ying Li, Mohammed M. Almutairi, Hong-Lian Shi, Qi Wang and Ming Hong

    Citation: Chinese Medicine 2019 14:27

    Content type: Research

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  26. Leflunomide (LEF) is a first-line disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, there are still a few nonresponders. It is logical to suggest that employing combinations ...

    Authors: Chi Zhang, Daogang Guan, Miao Jiang, Chao Liang, Li Li, Ning Zhao, Qinglin Zha, Wandong Zhang, Cheng Lu, Ge Zhang, Jian Liu and Aiping Lu

    Citation: Chinese Medicine 2019 14:26

    Content type: Research

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  27. Acanthopanacis Senticosi Radix et Rhizoma seu Caulis, the dried root and rhizome or stem of Acanthopanax senticosus, is commonly known as Siberian ginseng or Ciwujia in Chinese. It is used all over the world as a...

    Authors: Kit-Man Lau, Grace Gar-Lee Yue, Yuk-Yu Chan, Hin-Fai Kwok, Si Gao, Chun-Wai Wong and Clara Bik-San Lau

    Citation: Chinese Medicine 2019 14:25

    Content type: Review

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  28. Depression is the most disastrous mood disorder affecting the health of individuals. Conventional treatments with chemical compounds for depression have limitations, while herbal medicine has unique therapeuti...

    Authors: Zhengrong Zhang, Taomei Deng, Manli Wu, Aisong Zhu and Guoqi Zhu

    Citation: Chinese Medicine 2019 14:24

    Content type: Review

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  29. Inflammatory bowel disease (IBD) is an idiopathic intestinal inflammatory disease that comprises ulcerative colitis (UC) and Crohn’s disease (CD). IBD involves the ileum, rectum, and colon, and common clinical...

    Authors: Caifang Gao, Lijuan Liu, Yangyang Zhou, Zhaoxiang Bian, Shengpeng Wang and Yitao Wang

    Citation: Chinese Medicine 2019 14:23

    Content type: Review

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  30. Sanguisorba officinalis, a popular Chinese herb, called DiYu, has been shown to inhibit the growth of many human cancer cell lines, including colorectal cancer cells. The aims of this study were to discover the a...

    Authors: Wa Li, Chun-juan Yang, Li-qian Wang, Juan Wu, Cong Dai, Yue-mei Yuan, George Q. Li and Mei-cun Yao

    Citation: Chinese Medicine 2019 14:22

    Content type: Research

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  31. Panax ginseng is widely used as functional food and traditional Chinese medicine. To satisfy the market supply and medication safety, biofertilizers are used as agents to stimulate the growth and production of P....

    Authors: Linlin Dong, Yong Li, Jiang Xu, Juan Yang, Guangfei Wei, Liang Shen, Wanlong Ding and Shilin Chen

    Citation: Chinese Medicine 2019 14:20

    Content type: Research

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  32. Alzheimer’s disease (AD) is a common human neurodegenerative disease, which is characterized by the progressive loss of memory and the cognitive impairment. Since the etiology of AD is still unknown, it is ext...

    Authors: Cheong-Meng Chong, Huanxing Su, Jin-Jian Lu and Yitao Wang

    Citation: Chinese Medicine 2019 14:19

    Content type: Review

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  33. Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, which is commonly treated with antidiarrhoeal, antispasmodics, serotonergic agents or laxative agents. These treatments provide ...

    Authors: Xianwei Lin, Xia Liu, Jingjing Xu, Kian-Kai Cheng, Jianan Cao, Tao Liu, Qiong Liu, Huan Zhong, Guiping Shen, Jiyang Dong and Xiaorong Chang

    Citation: Chinese Medicine 2019 14:18

    Content type: Research

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  34. Cyathulae Radix (CR), also known as “Chuanniux” is a well-known traditional Chinese herbal medicine that has been used in China for thousands of years. The present work reviewed advances in traditional uses, o...

    Authors: Yongliang Huang, Shanshan Wang, Li Liu, Wei Peng, Jiaolong Wang, Ying Song, Qianghua Yuan, Xing Yuan and Chunjie Wu

    Citation: Chinese Medicine 2019 14:17

    Content type: Review

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  35. This study aims to assess clinical characteristics in FD with spleen deficiency syndrome and metabolic perturbations involved in FD progress. We combined metabolic biomarkers and clinical features into a bette...

    Authors: Jiaqi Zhang, Xue Wang, Xiaoshuang Shi, Jingyi Xie, Min Zhang, Jinxin Ma, Fengyun Wang and Xudong Tang

    Citation: Chinese Medicine 2019 14:16

    Content type: Research

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  36. Major depressive disorder (MDD) is highly heterogeneous in pathogenesis and manifestations. Further classification may help characterize its heterogeneity. We previously have shown differential metabolomic pro...

    Authors: Lan-Ying Liu, Xiao-Pei Xu, Li-Yuan Luo, Chun-Qing Zhu, Ya-Ping Li, Pei-Rong Wang, Yuan-Yuan Zhang, Chun-Yu Yang, Hong-Tao Hou, Yu-Lin Cao, Gang Wang, Edward S. Hui and Zhang-Jin Zhang

    Citation: Chinese Medicine 2019 14:15

    Content type: Research

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  37. The simple and caged xanthones from Clusiaceae showed significant antineoplastic activity. This study aims to identify structural diverse xanthones and search for novel antitumor natural products from this fam...

    Authors: Cuicui Jia, Chi Gong, Hong Chen, Jing Pu, Dahong Li, Zhanlin Li and Huiming Hua

    Citation: Chinese Medicine 2019 14:14

    Content type: Research

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  38. The discovery of bioactive compounds in traditional Chinese medicine (TCM) has become an important field in TCM modernization. Ligand fishing is a suitable method for discovery of bioactive compounds in comple...

    Authors: Shangxin Guo, Xiaotong Lin, Yi Wang and Xingchu Gong

    Citation: Chinese Medicine 2019 14:13

    Content type: Research

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  39. Water extract (WAE) and ultrafine powder (UFP) are two types of commonly used supplements in preparing various pharmaceutical products and functional foods. However, the correlations of the chemical compositio...

    Authors: Zhi Xin Li, Guan Ding Zhao, Wei Xiong, Ke Gang Linghu, Qiu Shuo Ma, Wai San Cheang, Hua Yu and Yitao Wang

    Citation: Chinese Medicine 2019 14:12

    Content type: Research

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  40. Biofilm is a natural form of bacterial growth ubiquitously in environmental niches. The biofilm formation results in increased resistance to negative environmental influences including resistance to antibiotic...

    Authors: Lan Lu, Wei Hu, Zeru Tian, Dandan Yuan, Guojuan Yi, Yangyang Zhou, Qiang Cheng, Jie Zhu and Mingxing Li

    Citation: Chinese Medicine 2019 14:11

    Content type: Review

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  41. Homeostasis is a crucial concept used to describe the condition of patients and the roles of herbs in traditional Chinese medicine. Qi-deficiency pattern is one of the conditions when loss of homeostasis and i...

    Authors: Pin-Hao Ko, Chiung-Wei Huang, Hen-Hong Chang, Eric Y. Chuang, Mong-Hsun Tsai and Liang-Chuan Lai

    Citation: Chinese Medicine 2019 14:10

    Content type: Research

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  42. Dryopteris crassirhizoma Nakai and Osmunda japonica Thunb. are ferns that are popularly used for medicine, as recorded by the Chinese pharmacopoeia, and are distributed in different regions of China. However, O. ...

    Authors: Liang Xu, Yanping Xing, Bing Wang, Chunsheng Liu, Wenquan Wang and Tingguo Kang

    Citation: Chinese Medicine 2019 14:9

    Content type: Research

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  43. Nowadays, traditional Chinese medicines (TCMs) have been reported to provide reliable therapies for viral pneumonia, but the therapeutic mechanism remains unknown. As a systemic approach, metabolomics provides...

    Authors: Lili Lin, Hua Yan, Jiabin Chen, Huihui Xie, Linxiu Peng, Tong Xie, Xia Zhao, Shouchuan Wang and Jinjun Shan

    Citation: Chinese Medicine 2019 14:8

    Content type: Review

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  44. Shikonin (SKN), a naphthoquinone compound, is isolated from Chinese herbal medicine Lithospermum root and has been studied as an anticancer drug candidate in human tumor models. This study is designed to investig...

    Authors: Zhu Wang, Jianhua Yin, Mingxing Li, Jing Shen, Zhangang Xiao, Yueshui Zhao, Chengliang Huang, Hanyu Zhang, Zhuo Zhang, Chi Hin Cho and Xu Wu

    Citation: Chinese Medicine 2019 14:7

    Content type: Research

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  45. Fuzi-Lizhong pill (FZLZP), which was first recorded in the Classic–“Taiping Huimin Heji Ju Fang” of the Song Dynasty, has been widely used to treat gastrointestinal disease in clinic for thousands of years in ...

    Authors: Zhen Zhang, Maoyuan Jiang, Xinyi Wei, Jinfeng Shi, Zhao Geng, Shasha Yang, Chaomei Fu and Li Guo

    Citation: Chinese Medicine 2019 14:6

    Content type: Research

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  46. Baduanjin, a traditional Chinese exercise therapy, has been widely used in China to treat type 2 diabetes (T2DM) with depression (DD). However, the underlying mechanism of Baduanjin in anti-DD is unclear. This...

    Authors: Tian An, Zhong-Chen He, Xin-Qing Zhang, Jun Li, Ai-Ling Chen, Fang Tan, Hong-Dong Chen, Bo-Han Lv, Juan Lian, Si-Hua Gao and Guang-Jian Jiang

    Citation: Chinese Medicine 2019 14:3

    Content type: Research

    Published on: