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  1. Non–small cell lung cancer is associated with high expression of multidrug resistance (MDR) proteins and low production of reactive oxygen species (ROS). Coptis extract (COP), a Chinese medicinal herb, and its ma...

    Authors: Chengwei He, Rong Rong, Jing Liu, Jianbo Wan, Keyuan Zhou and Jing X Kang
    Citation: Chinese Medicine 2012 7:11
  2. Flavonoids, a group of compounds mainly derived from vegetables and herbal medicines, chemically resemble estrogen and some have been used as estrogen substitutes. Kaempferol, a flavonol derived from the rhizo...

    Authors: Ava Jiangyang Guo, Roy Chiyan Choi, Ken Yuzhong Zheng, Vicky Ping Chen, Tina Tingxia Dong, Zheng-Tao Wang, Günter Vollmer, David Taiwai Lau and Karl Wah-keung Tsim
    Citation: Chinese Medicine 2012 7:10
  3. There is a long history of coronary heart disease (CHD) diagnosis and treatment in Chinese medicine (CM), but a formalized description of CM knowledge is still unavailable. This study aims to analyze a set of ...

    Authors: Guo-Zheng Li, Sheng Sun, Mingyu You, Ya-Lei Wang and Guo-Ping Liu
    Citation: Chinese Medicine 2012 7:9
  4. Red yeast rice (i.e., rice fermented with Monascus spp.), as a food supplement, is claimed to be blood cholesterol-lowering. The red yeast rice constituent monacolin K, also known as lovastatin, is an inhibitor o...

    Authors: Dirk W Lachenmeier, Yulia B Monakhova, Thomas Kuballa, Sigrid Löbell-Behrends, Sibylle Maixner, Matthias Kohl-Himmelseher, Asja Waldner and Christian Steffen
    Citation: Chinese Medicine 2012 7:8
  5. Radix Salvia miltiorrhiza (Danshen) has been used as a principal herb in treating cardiovascular diseases in Chinese medicine. Salvianolic acid B (SA-B), a water-soluble active component of Danshen, was found to ...

    Authors: Yonghai Lu, Yue Zheng, Xinru Liu, Xu Liang, Saiming Ngai, Tiejun Li and Weidong Zhang
    Citation: Chinese Medicine 2012 7:6
  6. The studies on the effectiveness of Chinese herbal medicines (CHM) in treating liver fibrosis (LF) were not consistent. This study aims to systematically review the effectiveness of CHM on treating LF patients.

    Authors: Fan Cheung, Yibin Feng, Ning Wang, Man-Fung Yuen, Yao Tong and Vivian Taam Wong
    Citation: Chinese Medicine 2012 7:5
  7. The existence of point specificity in acupuncture is controversial, because many acupuncture studies using this principle to select control points have found that sham acupoints have similar effects to those o...

    Authors: Emma M Choi, Fang Jiang and John C Longhurst
    Citation: Chinese Medicine 2012 7:4
  8. The stimulation of acupoints along the meridians, but not the non-acupoints outside of the meridians, produces analgesia. Although the acupoint is defined at the body surface, the exact location of the acupoin...

    Authors: Marcelo L Silva, Josie RT Silva and Wiliam A Prado
    Citation: Chinese Medicine 2012 7:3
  9. Ginsenosides, the bioactive components of ginseng, can be divided into two major groups, namely 20(S)-protopanaxatriol (e.g. Re, Rg1, Rg2, and Rb3) and 20(S)-protopanaxadiol (e.g. Rb1, Rb2, Rc, and Rd). Biologica...

    Authors: Dacheng Peng, Huashan Wang, Chenling Qu, Laihua Xie, Sheila M Wicks and Jingtian Xie
    Citation: Chinese Medicine 2012 7:2
  10. Two active compounds, baicalein and its glycoside baicalin were found in the dried root of Scutellaria baicalensis Georgi, and reported to be neuroprotective in vitro and in vivo. This study aims to evaluate the ...

    Authors: Ju-Xian Song, Mandy Yuen-Man Choi, Kavin Chun-Kit Wong, Winkie Wing-Yan Chung, Stephen Cho-Wing Sze, Tzi-Bun Ng and Kalin Yan-Bo Zhang
    Citation: Chinese Medicine 2012 7:1
  11. Chinese medicinal materials may be authenticated by molecular identification. As a definitive approach to molecular identification of medicinal materials, forensically informative nucleotide sequencing (FINS) ...

    Authors: Ming Li, Kalin Yan-Bo Zhang, Paul Pui-Hay But and Pang-Chui Shaw
    Citation: Chinese Medicine 2011 6:42
  12. The prevalence and risk of cardiovascular disease increase after menopause in correlation with the progression of abnormality in the serum lipid profile and the deprivation of estrogen. Erxian decoction (EXD), a ...

    Authors: Stephen CW Sze, Ho-Pan Cheung, Tzi-Bun Ng, Zhang-Jing Zhang, Kam-Lok Wong, Hei-Kiu Wong, Yong-Mei Hu, Christine MN Yow and Yao Tong
    Citation: Chinese Medicine 2011 6:40
  13. Six plants from Thailand were evaluated for their cytotoxicity and apoptosis induction in human hepatocarcinoma (HepG2) as compared to normal African green monkey kidney epithelial cell lines.

    Authors: Sasipawan Machana, Natthida Weerapreeyakul, Sahapat Barusrux, Apiyada Nonpunya, Bungorn Sripanidkulchai and Thaweesak Thitimetharoch
    Citation: Chinese Medicine 2011 6:39
  14. Panax notoginseng is commonly used for the treatment of cardiovascular diseases in China. The present study investigates the effects of three different saponin fractions (ie total saponins, PNS; protopanaxadiol-t...

    Authors: Nan Wang, Jian-Bo Wan, Shun-Wan Chan, Yan-Hui Deng, Nan Yu, Qing-Wen Zhang, Yi-Tao Wang and Simon Ming-Yuen Lee
    Citation: Chinese Medicine 2011 6:37
  15. Interstitial pulmonary fibrosis is characterized by an altered cellular composition of the alveolar region with excessive deposition of collagen. Lung inflammation is also common in pulmonary fibrosis. This st...

    Authors: Eman Noaman Ali and Somaya Zakaria Mansour
    Citation: Chinese Medicine 2011 6:36
  16. Peanut allergy is characterized by increased levels of peanut-specific IgE in the serum of most patients. Thus, the most logical therapy would be to inhibit the IgE production by committed B-cells. This study ...

    Authors: Iván López-Expósito, Alexandra Castillo, Nan Yang, Banghao Liang and Xiu-Min Li
    Citation: Chinese Medicine 2011 6:35
  17. Chotosan (CTS, Diaoteng San), a Kampo medicine (ie Chinese medicine) formula, is reportedly effective in the treatment of patients with cerebral ischemic insults. This study aims to evaluate the therapeutic poten...

    Authors: Qi Zhao, Takako Yokozawa, Koichi Tsuneyama, Ken Tanaka, Takeshi Miyata, Notoshi Shibahara and Kinzo Matsumoto
    Citation: Chinese Medicine 2011 6:33
  18. Curcumin has attracted great attention in the therapeutic arsenal in clinical oncology due to its chemopreventive, antitumoral, radiosensibilizing and chemosensibilizing activities against various types of agg...

    Authors: Murielle Mimeault and Surinder K Batra
    Citation: Chinese Medicine 2011 6:31
  19. Infantile colic is a common painful clinical condition associated with signs of distended intestines and an increase in colon peristalsis. However, clinical documentation of observed gastrointestinal functions...

    Authors: Marianne Reinthal, Iréne Lund, Dacil Ullman and Thomas Lundeberg
    Citation: Chinese Medicine 2011 6:28
  20. In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiti...

    Authors: Wen Tan, Jinjian Lu, Mingqing Huang, Yingbo Li, Meiwan Chen, Guosheng Wu, Jian Gong, Zhangfeng Zhong, Zengtao Xu, Yuanye Dang, Jiajie Guo, Xiuping Chen and Yitao Wang
    Citation: Chinese Medicine 2011 6:27
  21. Since oxidative stress has been implicated in a neurodegenerative disease such as Alzheimer's disease (AD), natural antioxidants are promising candidates of chemopreventive agents. This study examines antioxid...

    Authors: Chang-Ho Jeong, Hee Rok Jeong, Gwi Nam Choi, Dae-Ok Kim, Uk Lee and Ho Jin Heo
    Citation: Chinese Medicine 2011 6:25
  22. While evidence supports efficacy of acupuncture and/or dry needling in treating musculoskeletal pain, it is unclear which needling method is most effective. This study aims to determine the effects of depth of...

    Authors: Kazunori Itoh, Yoichi Minakawa and Hiroshi Kitakoji
    Citation: Chinese Medicine 2011 6:24
  23. Hypertension is a clinical condition that manifests target-organ damage (TOD) with symptoms. This study investigates the association between Zangfu patterns and symptomatic manifestations of TOD.

    Authors: Alexandre Bastos Luiz, Ivan Cordovil, José Barbosa Filho and Arthur Sá Ferreira
    Citation: Chinese Medicine 2011 6:23
  24. Immuno-modulatory effects of ginseng, including both immuno-stimulatory and immuno-suppressive effects, have been widely reported. This study aims to determine whether the paradoxical immuno-modulatory effect ...

    Authors: Chike Godwin Azike, Paul Abrahams Charpentier, Jirui Hou, Hua Pei and Edmund Man King Lui
    Citation: Chinese Medicine 2011 6:21
  25. Oleanolic acid (OA) is a natural triterpenoid possessing anti-inflammatory, antitumor, antiviral, hepatoprotective and antihyperlipidemic effects. Research on the pharmacological activities and clinical applic...

    Authors: Meiwan Chen, Zhangfeng Zhong, Wen Tan, Shengpeng Wang and Yitao Wang
    Citation: Chinese Medicine 2011 6:20
  26. The present study investigates the effects of ginsenosides Rh1 and Rg2 against 6-hydroxydopamine (6-OHDA), a neurotoxin on SH-SY5Y cells and PC-12 cells. The effects of these two ginsenosides on neuronal differen...

    Authors: Xiao-Fan Li, Cathy Nga-Ping Lui, Zhi-Hong Jiang and Yung Kin-Lam Ken
    Citation: Chinese Medicine 2011 6:19
  27. Poor quality control of medicinal herbs has led to instances of toxicity, poisoning and even deaths. The fundamental step in quality control of herbal medicine is accurate identification of herbs. Array-based ...

    Authors: Linhai Niu, Nitin Mantri, Chun Guang Li, Charlie Xue and Edwin Pang
    Citation: Chinese Medicine 2011 6:18
  28. Eczema is a chronic relapsing atopic dermatitis (AD) associated with pruritus, sleep disturbance and poor quality of life of the patient. Treatment of eczema includes use of emollient, topical and systemic ant...

    Authors: Kam Lun Hon, Ben Chung-Lap Chan and Ping Chung Leung
    Citation: Chinese Medicine 2011 6:17
  29. Ericaulon buergerianum (Gujingcao) is an ophthalmic, anti-inflammatory and antimicrobial Chinese medicinal herb. This study aims to investigate the neuroprotective effects of Ericaulon buergerianum ethanol extrac...

    Authors: Meiwei Wang, Zaijun Zhang, Lorita Chi-Veng Cheang, Zhixiu Lin and Simon Ming-Yuen Lee
    Citation: Chinese Medicine 2011 6:16
  30. Upon initial infection with mycobacteria, macrophages secrete multiple cytokines and chemokines, including interleukin-6 (IL-6), IL-8 and tumor necrosis factor-α (TNF-α), to mediate host immune responses again...

    Authors: Liangjie Wang, Cindy Lai Hung Yang, Terry Cho Tsun Or, Gang Chen, Jian Zhou, James Chun Tsun Li and Allan Sik Yin Lau
    Citation: Chinese Medicine 2011 6:14
  31. Active myofascial trigger points are one of the major peripheral pain generators for regional and generalized musculoskeletal pain conditions. Myofascial trigger points are also the targets for acupuncture and...

    Authors: Hong-You Ge, César Fernández-de-las-Peñas and Shou-Wei Yue
    Citation: Chinese Medicine 2011 6:13
  32. Arctium lappa (Niubang), a Chinese herbal medicine, is used to treat tissue inflammation. This study investigates the effects of arctigenin (AC), isolated from A. lappa, on anti-CD3/CD28 Ab-stimulated cell prolif...

    Authors: Wei-Jern Tsai, Chu-Ting Chang, Guei-Jane Wang, Tzong-Huei Lee, Shwu-Fen Chang, Shao-Chun Lu and Yuh-Chi Kuo
    Citation: Chinese Medicine 2011 6:12
  33. An aqueous extract of multi-hypoglycemic herbs of Panax ginseng C.A.Meyer, Pueraria lobata, Dioscorea batatas Decaisne, Rehmannia glutinosa, Amomum cadamomum Linné, Poncirus fructus and Evodia officinalis was inv...

    Authors: Jiyoung Yeo, Young-Mi Kang, Su-In Cho and Myeong-Ho Jung
    Citation: Chinese Medicine 2011 6:10
  34. EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from isc...

    Authors: Jiangang Shen, Waisin Lee, Yong Gu, Yao Tong, Peter CW Fung and Li Tong
    Citation: Chinese Medicine 2011 6:8
  35. Danshen-Gegen decoction (DG), a Chinese herbal formula, has been demonstrated to be effective for the treatment of coronary heart disease such as myocardial infarction. In the present study, we investigated the e...

    Authors: Sze Man Wong, Po Yee Chiu, Hoi Yan Leung, Limin Zhou, Zhong Zuo, Philip Y Lam and Kam Ming Ko
    Citation: Chinese Medicine 2011 6:7
  36. This article reviews the anti-inflammatory relative and anti-infectious effects of Evodia rutaecarpa and its major bioactive components and the involvement of the nitric oxide synthases, cyclooxygenase, NADPH oxi...

    Authors: Jyh-Fei Liao, Wen-Fei Chiou, Yuh-Chiang Shen, Guei-Jane Wang and Chieh-Fu Chen
    Citation: Chinese Medicine 2011 6:6
  37. Panax notoginseng is an important Chinese medicinal plant. Dammarene-type triterpenoid saponins are main pharmacologically effective compounds in P. notoginseng. This study aims to investigate the formation and a...

    Authors: Dong Wang, Hongtao Zhu, Keke Chen, Min Xu, Yingjun Zhang and Chongren Yang
    Citation: Chinese Medicine 2011 6:5