While DNA barcoding is an important technology for the authentication of the botanical origins of Chinese medicines, the suitable markers for DNA barcoding of the genus Uncaria have not been reported yet. This st...
Authors: Yin-lin Tang, Yao-sheng Wu, Rui-song Huang, Nai-xia Chao, Yong Liu, Peng Xu, Ke-zhi Li, Dan-zhao Cai and Yu Luo
Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia–Pacific region. In Chinese medicine, HFM...
Cycloartane triterpenoids exhibited anticancer effects. This study aims to identify any potential novel anticancer cycloartane triterpenoids from Cimicifuga foetida L. rhizome (Sheng ma) and the mode of actions.
Authors: Hai-yan Sun, Bei-bei Liu, Jian-yang Hu, Li-jia Xu, Shun-wan Chan, Chi-on Chan, Daniel K. W. Mok, Dong-mei Zhang, Wen-cai Ye and Si-bao Chen
Huangqi decoction (HQD) is used for liver fibrosis and cirrhosis treatment in Chinese medicine. This study aims to investigate the pharmacological actions of HQD against liver fibrosis...
Authors: Gui-biao Zhang, Ya-nan Song, Qi-long Chen, Shu Dong, Yi-yu Lu, Ming-yu Su, Ping Liu and Shi-bing Su
This study aims to analyze the active pharmaceutical ingredients (APIs) of licorice (Radix Glycyrrhizae; gancao), including glycyrrhizic acid, liquiritin, isoliquiritin and total flavonoids, in multi-ingredient a...
Authors: Yang Li, Mingye Guo, Xinyuan Shi, Zhisheng Wu, Jianyu Li, Qun Ma and Yanjiang Qiao
Some isoquinoline alkaloids from Macleaya cordata (Willd). R. Br. (Bo Luo Hui) exhibited antibacterial, antiparasitic, antitumor, and analgesic effects. The targets of these isoquinoline alkaloids are undefined. ...
Authors: Qifang Lei, Haibo Liu, Yong Peng and Peigen Xiao
The outcome of acupuncture on hypertension treatment is inconclusive. This study aims to evaluate the influence of acupuncture on hypertension, based on findings from mechanistic studies over the course of dec...
Authors: Ling Cheng, Peng Li, Stephanie Cheeyee Tjen-A-Looi and John Charles Longhurst
The radix of Glehnia littoralis Fr. Schmidt ex Miq. (Beishashen), is often misidentified and adultered in Chinese medicine. Its seven common adulterants include Chuanminshen violaceum Sheh et Shan (Chuanmingshen)...
The fresh leaves of Eucalyptus globulus Labill. (Lan An) have been used in Chinese medicine for many years to treat dermatomycosis. Macrocarpal C was isolated from this herb and identified as its major antifungal...
Authors: Jack Ho Wong, Kit-Man Lau, Yu-On Wu, Ling Cheng, Chun-Wai Wong, David Tai-Wai Yew, Ping-Chung Leung, Kwok-Pui Fung, Mamie Hui, Tzi-Bun Ng and Clara Bik-San Lau
Deer tendons are believed more effective than cattle tendons in tonifying kidney yang (shen yang) and enhancing bone and tendons. This study aims to differentiate the two types of tendons by a loop-mediated isoth...
Constipation has a high prevalence rate (>30 %) in psychiatric patients with psychotropic drugs. Common pharmacological and non-pharmacological interventions for constipation might have longer-term negative an...
Authors: Wai Kit Wong, Wai Tong Chien and Wai Ming Lee
People seek Chinese medicine (CM) treatments for a variety of respiratory disorders, e.g., asthma and upper respiratory tract infection (URTI). No previous studies have reviewed the data available in medical r...
Authors: Wan Najbah Nik Nabil, Wenyu Zhou, Johannah Linda Shergis, Suzi Mansu, Charlie Changli Xue and Anthony Lin Zhang
Infections such as common colds, influenza, acute upper respiratory infections, bacterial gastroenteritis, and urinary tract infections are usually diagnosed according to patients’ signs and symptoms. This stu...
Authors: Pei-Jung Chiang, Tsai-Chung Li, Chih-Hung Chang, Li-Li Chen, Jun-Dai Lin and Yi-Chang Su
Qing-dai powder (QDP), comprising Indigo naturalis (Qing-dai) and dried alum (Ku-fan), was used in Chinese medicine to treat the conditions associated with mucosal hemorrhage, such as ...
Authors: Hai-Tao Xiao, Jiao Peng, Dong-Dong Hu, Cheng-Yuan Lin, Bin Du, Siu-Wai Tsang, Ze-si Lin, Xiao-Jun Zhang, Feng-Ping Lueng, Quan-Bin Han and Zhao-Xiang Bian
The morphological identification of different Hippophae species (Shaji) was difficult. This study aims to discriminate between medicinal and non-medicinal Hippophae species by DNA barcodes, the ITS2, psbA-trnH, a...
Authors: Yue Liu, Wei Sun, Chuan Liu, Yaqin Zhang, Yilong Chen, Ming Song, Gang Fan, Xia Liu, Li Xiang and Yi Zhang
The combination of a Chinese herbal medicine (CHM) bath and narrowband ultraviolet B (NB-UVB) improved the efficacy of NB-UVB treatment of psoriasis vulgaris, but bath therapy is inconvenient. Oral CHM plus NB...
Authors: Lihong Yang, Claire Shuiqing Zhang, Brian May, Jingjie Yu, Xinfeng Guo, Anthony Lin Zhang, Charlie Changli Xue and Chuanjian Lu
Centipeda minima (Ebushicao) has been used for the treatment of various diseases, such as nasal allergies, rhinitis and sinusitis, nasopharyngeal carcinoma, cough, and headache. This s...
The green speckled lentil seed (Lens culinaris) lectin (GSLL) exhibits hemagglutinating activity, and possesses some properties distinct from those of other lentil lectins (e.g., molecular size, biological activi...
Authors: Yau Sang Chan, Huimin Yu, Lixin Xia and Tzi Bun Ng
Liver-gallbladder dampness-heat (LGDH) and liver kidney yin deficiency (LKYD) syndromes are Chinese medicine (CM) zhengs in chronic hepatitis B (CHB) patients. This study aims to inves...
Authors: Yi-Yu Lu, Yu Zhao, Ya-Nan Song, Shu Dong, Bin Wei, Qi-Long Chen, Yi-Yang Hu and Shi-Bing Su
Ilex latifolia Thunb. (Da Ye Dong Qing) is used for weight loss and for its antidiabetic effects. This study aims to investigate the beneficial effects and potential mechanisms of acti...
Authors: Rui-Bing Feng, Chun-Lin Fan, Qing Liu, Zhong Liu, Wei Zhang, Yao-Lan Li, Wei Tang, Ying Wang, Man-Mei Li and Wen-Cai Ye
DNA barcoding can be used to
authenticate Ganoderma species for safe use. This study aims to identify commercial products containing Ganoderma using DNA barcoding.
Authors: Baosheng Liao, Xiaochen Chen, Jianping Han, Yang Dan, Lili Wang, Wenjing Jiao, Jingyuan Song and Shilin Chen
Postinfectious cough (PIC) significantly affects cough-related quality of life but still lacks effective treatments. This study aims to investigate the efficacy of QingfengGanke granule (QFGKG) in treating PIC in...
Authors: Hongli Jiang, Bing Mao, Lei Wang, Ruiming Zhang, Bin She, Faguang Jin, Yanling Xu, Jian Ma and Qiuping Liu
Anemone flaccida Fr
. Schmidt (Ranunculaceae) (Di Wu in Chinese) is used to treat punch injury and rheumatoid arthritis (RA). However, the active compounds and underlying mechanism of ...
Authors: Qing Liu, Xiu-Zhen Zhu, Rui-Bing Feng, Zhong Liu, Gui-Yang Wang, Xi-Feng Guan, Guo-min Ou, Yao-Lan Li, Ying Wang, Man-Mei Li and Wen-Cai Ye
Erxian decoction (EXD) is used to treat menopause-related symptoms in Chinese medicine. This study aims to identify the bioactive compounds and potential actions of EXD by network phar...
Authors: Shiwei Wang, Yao Tong, Tzi-Bun Ng, Lixing Lao, Jenny Ka Wing Lam, Kalin Yanbo Zhang, Zhang-Jin Zhang and Stephen Cho Wing Sze
This study aims to evaluate the efficacy of Xiaoyaosan (XYS) for treatment of major depressive disorder (MDD) and to review the studies on antidepressant mechanisms of XYS.
Authors: Lin-Lin Jing, Xiao-Xia Zhu, Zhi-Ping Lv and Xue-Gang Sun
This study aims to investigate the leukogenic effect of astragalus polysaccharide (APS), to compare its effect of increasing the numbers of mature granulocytes with that of granulocyte colony-stimulating facto...
Authors: Ping-Ping Zhang, Zhao-Ting Meng, Liu-Chun Wang, Lei-Ming Guo and Kai Li
The Chinese medicine herb pair Flos Lonicerae japonicae (FLJ) and Forsythiae fructus (FF), is a representative heat-clearing (qing re) and detoxifying (jie du) combination that exhibits many pharmacological activ...
Panax Notoginseng flower saponins (PNFS) are the main active component of Panax notoginseng (Burk) F. H. Chen flower bud (PNF) and possess significant anti-inflammatory efficacy. This ...
Authors: Xiao-Xu Peng, Shu-Hui Zhang, Xiao-Ling Wang, Ting-Jie Ye, Hua Li, Xiao-Feng Yan, Li Wei, Zhong-Ping Wu, Jing Hu, Chun-Pu Zou, You-Hua Wang and Xu-Dong Hu
Ougan (Citrus reticulata cv. Suavissima) flavedo extract (OFE) exhibited potential anti-tumor effects with unclear underlying mechanisms. This study aims to evaluate the potential anti-metastatic activities of OF...
Authors: Linlin Chang, Sheng Jia, Yingying Fu, Tianyi Zhou, Ji Cao, Qiaojun He, Bo Yang, Xian Li, Chongde Sun, Dan Su, Hong Zhu and Kunsong Chen
Granule products produced from medicinal herbs are gaining popularity. However, there have been few studies comparing the quality or efficacy of granules with those of herbal formulations. This study aims to c...
Authors: Xian Zhou, Valentina Razmovski-Naumovski and Kelvin Chan
Acupuncture and moxibustion are more integrated in the Chinese healthcare system than in the national healthcare systems of other countries. Development of acupuncture and moxibustion in China is making progre...
Authors: Min Yee Lim, Jian Huang, Baixiao Zhao and Lue Ha
Qing-Yi Decoction (QYD) has been used for severe acute pancreatitis (SAP) patients in China for many years. There were two kinds of QYD: Num 1. QYD (QYD1) which is used in the acute response st...
Authors: Weiwei Chen, Xiaonan Yang, Lei Huang, Ping Xue, Meihua Wan, Jia Guo, Lin Zhu, Tao Jin, Zongwen Huang, Guangyuan Chen, Wenfu Tang and Qing Xia
You-Gui pills (You-Gui-Wan; YGW) can promote T lymphocyte proliferation and differentiation, and restore Th1/Th2 balance in the treatment of asthma, but their mechanism of action is not fully known. This study ai...
Authors: Hong Ping Zhang, Juan Juan Fu, Tao Fan, Wen Bin Zhang, Zeng Li Wang, Lei Wang and Gang Wang
Sterol regulatory element binding protein-1c (SREBP-1c) is a regulator of the lipogenic pathway and is transcriptionally activated by liver X receptor α (LXRα). This study aims to investigate phytochemicals in...
Authors: Gyun-Sik Oh, Gang Gu Lee, Jin Yoon, Won Keun Oh and Seung-Whan Kim
Liver fibrosis is a wound-healing response to chronic liver injury characterized by progressive inflammation and deposition of extracellular matrix components. The pathological condition of liver fibrosis invo...
Authors: Shao-Ru Chen, Xiu-Ping Chen, Jin-Jian Lu, Ying Wang and Yi-Tao Wang
Kaempferol has been reported as beneficial for both acute and chronic inflammatory diseases. This study aims to investigate whether kaempferol affects systemic inflammation and oxidative stress in the heart, l...
Authors: Qi-Sheng Yang, Li-Ping He, Xian-Long Zhou, Yan Zhao, Jun Shen, Peng Xu and Shao-Zhou Ni
Bufothionine is an alkaloid in Cinobufacini (Huachansu). This study aims to investigate the effects of bufothionine on liver tumors and acute liver injury.
Authors: Rui-Fang Xie, Zhi-Cheng Li, Pei-Pei Chen and Xin Zhou
Chrysin (5,7-dihydroxyflavone) inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation and arterial intima hyperplasia. This study aims to investigate the effects of chrysin o...
Authors: Xian-Wei Li, Xiang-Ming Wang, Shu Li and Jie-Ren Yang
Pineapple (Ananas comosus) was demonstrated to be hepatoprotective. This study aims to investigate the reversing effects of pineapple vinegar on paracetamol-induced liver damage in murine model.
Authors: Nurul Elyani Mohamad, Swee Keong Yeap, Kian Lam Lim, Hamidah Mohd Yusof, Boon Kee Beh, Sheau Wei Tan, Wan Yong Ho, Shaiful Adzni Sharifuddin, Anisah Jamaluddin, Kamariah Long, Nik Mohd Afizan Nik Abd Rahman and Noorjahan Banu Alitheen
Rhizoma Chuanxiong (RC) is the dried rhizome of Ligusticum chuanxiong Hort., and various types of processed Rhizoma Chuanxiong (PRC) are widely used in China. However, quality assurance and quality control of the...
Authors: Jia-Yan Fang, Lin Zhu, Tao Yi, Jian-Ye Zhang, Ling Yi, Zhi-Tao Liang, Li Xia, Jia-Fu Feng, Jun Xu, Yi-Na Tang, Zhong-Zhen Zhao and Hu-Biao Chen
DNA in herbal decoctions is usually fragmented by extensive boiling and is usually regarded as unsuitable for molecular authentication. This study aims to evaluate the feasibility for molecular authentication ...
During chronic liver injury, hepatic stellate cells (HSC) are activated and proliferate, which causes excessive extracellular matrix (ECM) deposition, leading to scar formation and fibrosis. Medicinal plants a...
Authors: Florent Duval, Jorge E Moreno-Cuevas, María Teresa González-Garza, Carlos Rodríguez-Montalvo and Delia Elva Cruz-Vega
The total flavonoids from ethanol extract of the aerial part of Ziziphora clinopodioides Lam. (Lamlaceae) (Xintahua) showed protective activities against rat acute myocardial ischemia in rats. This study aims to ...
Authors: Wei-Jun Yang, Chong Liu, Zheng-Yi Gu, Xing-Yue Zhang, Bo Cheng, Yan Mao and Gui-Peng Xue
Wild Rheum tanguticum (Dahuang in Chinese) has becoming endangered in China. This study aims to examine the genetic structure and genetic diversity of R. tanguticum within species, and the genetic differentiation...
Authors: Xiaoqin Zhang, Ying Liu, Xuan Gu, Zhengzheng Guo, Li Li, Xiaona Song, Siqi Liu, Yimei Zang, Yanpeng Li, Chunsheng Liu and Shengli Wei
The land and ecology suitability for producing pollution-free Chinese medicinal materials should be evaluated based on Geographic Information System (GIS). This study aims to determine production regions for p...
Authors: Cai-xiang Xie, Huan Wang, Lin-fang Huang, Hui Li and Jing-yuan Song
The role of “Jun-Chen-Zuo-Shi” (also known as “sovereign-minister-assistant-courier”) component herbs of Chinese medicine is not fully understood. This study aims to test the “Jun-Chen-Zuo-Shi” rule with the QiSh...
Authors: Leihong Wu, Yi Wang, Zheng Li, Boli Zhang, Yiyu Cheng and Xiaohui Fan
The Chinese medicine formulation ISF-1 (also known as Bu-Yang-Huan-Wu-Tang) for post-stroke rehabilitation could increase the expression of growth-regulating protein follistatin by approximately 4-fold. This stud...
Authors: Chuanbin Yang, Xuechen Li and Jianhui Rong
This study interviewed community pharmacists in Shanghai and Guangzhou for their perception of the popular categories of over-the-counter (OTC) Chinese medicines and the factors affecting customer preferences ...
Chaihu, prepared from the dried roots of Bupleurum Chinense DC (also known as bei Chaihu in Chinese) or Bupleurum scorzoneraefolium WILD (also known as nan Chaihu in Chinese), is a herbal medicine for harmonizing...
Authors: Betty Yuen-Kwan Law, Jing-Fang Mo and Vincent Kam-Wai Wong
