As current symptomatic treatments of constipation are still unsatisfactory, an increasing number of patients seek help from Chinese medicine (CM), particularly Chinese herbal medicine (CHM). This study aimed t...
Authors: Linda L. D. Zhong, Guang Zheng, Li Da Ge, Cheng Yuan Lin, Tao Huang, Ling Zhao, Cheng Lu, Ai Ping Lu and Zhao Xiang Bian
Gastrodia and Uncaria decoction (tianma gouteng yin) is commonly used in Chinese medicine to treat cerebral ischemia. The aim of this study was to investigate the neuroprotective effec...
Authors: Jia Wen Xian, Angus Yiu-Ting Choi, Clara Bik-San Lau, Wing Nang Leung, Chun Fai Ng and Chun Wai Chan
Rhizoma Chuanxiong (RC; Chuanxiong), which is the dried rhizome of Ligusticum chuanxiong (Umbelliferae), is commonly used in Chinese medicine (CM) for improving blood circulation and dispersing blood stasis. RC i...
Authors: Tao Yi, Jia-Yan Fang, Lin Zhu, Yi-Na Tang, Hong Ji, Ya-Zhou Zhang, Ju-Cheng Yu, Xiao-Jun Zhang, Zhi-Ling Yu, Zhong-Zhen Zhao and Hu-Biao Chen
Diabetes, associated with hyperlipidemia and oxidative stress, would lead to an increased production of reactive oxygen species. Rehmannia glutinosa (Di Huang) is widely used to nourish yin, invigorate the kidney
Authors: Huifeng Zhu, Yuan Wang, Zhiqiang Liu, Jinghuan Wang, Dong Wan, Shan Feng, Xian Yang and Tao Wang
Chronic fatigue (CF) reflects an imbalance of inter-organ functions or of the four essential physiological components qi, blood (xue), yin, and yang. CF can be subdivided into different patterns. However, there a...
Ganoderma lucidum (Lingzhi; LZ) and San-Miao-San (SMS) are Chinese medicines (CMs) used to treat inflammatory ailments and numbing syndrome/arthralgia syndrome (Bi Zheng), respectively...
Authors: Zhe Cai, Chun Kwok Wong, Jie Dong, Delong Jiao, Man Chu, Ping Chung Leung, Clara Bik San Lau, Ching Po Lau, Lai Shan Tam and Christopher Wai Kei Lam
Loki zupa (Luooukezupa) decoction, consisting of the roots of Hyssopuscuspidatus Boriss (Shenxiangcao) and Irishalophila Pall root (Yuanweigen), is commonly used in Uygur medicine to t...
Chinese medicinal herbs may use more than one species of Curcumae Radix (Yujin) is the tuberous roots of Curcumae wenyujin, C. kwangsiensis, C. phaeocaulis and C. longa. This study aimed to characterize the chemi...
Authors: Fang Liu, Xu Bai, Feng-Qing Yang, Xiao-Jing Zhang, Yuanjia Hu, Peng Li and Jian-Bo Wan
Herb-partitioned moxibustion (HPM) at Tianshu (ST25) and Qihai (RN6) has been used to treat Crohn’s disease (CD). Injury to intestinal epithelial tight junctions (TJs) is the leading cause of CD onset with under ...
Authors: Rong Ji, Anqi Wang, Haixia Shang, Liu Chen, Chunhui Bao, Luyi Wu, Huangan Wu and Yin Shi
Herbal plants are a preferred source of anticancer agents. This study aims to screen the anticancer activity of a crude extract of twigs of (a) Bombax anceps Pierre var. anceps (BA); (b) Catunaregam tomentosa (Bl...
Authors: Natthida Weerapreeyakul, Cholpajsorn Junhom, Sahapat Barusrux and Thaweesak Thitimetharoch
The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the ...
Authors: Hai Fang Chen, You Hua Chen, Chun Hua Liu, Lu Wang, Xi Chen, Bo Yang Yu and Jin Qi
SHINBARO is a refined herbal formulation used to treat inflamed lesions and bone diseases. This study aimed to investigate the anti-osteoarthritic activities of intra-articular administration of SHINBARO and d...
Authors: Won Kyung Kim, Hwa-Jin Chung, Yuna Pyee, Tae Jun Choi, Hyen Joo Park, Ji-Young Hong, Joon-Shik Shin, Jin Ho Lee, In-Hyuk Ha and Sang Kook Lee
Acupuncture therapy has been used to treat substance abuse. This study aims to review experimental studies examining the effects of acupuncture on addiction. Research and review articles on acupuncture treatme...
Authors: Farid Esmaeili Motlagh, Fatimah Ibrahim, Rusdi Abd Rashid, Tahereh Seghatoleslam and Hussain Habil
Jujube (Zǎo) seeds exhibited anticancer effects and used in Chinese medicine for many years. This study aims to investigate the apoptosis-inducing effects of seed extracts from eight different cultivated species ...
Authors: Natthanan Taechakulwanijya, Natthida Weerapreeyakul, Sahapat Barusrux and Sirithorn Siriamornpun
The discovery of anti-diabetic drugs is an active Chinese medicine research area. This study aims to map out anti-diabetic drug research in China using a network-based systemic approach based on co-authorship ...
Authors: Junling Deng, Kaweng Sitou, Yongping Zhang, Ru Yan and Yuanjia Hu
Certain Chinese medicine (CM) herbs and acupuncture may protect against Alzheimer’s disease (AD). However, there is a lack of research regarding the use of CM in patients with AD. The aim of this study was to ...
Authors: Shun-Ku Lin, Sui-Hing Yan, Jung-Nien Lai and Tung-Hu Tsai
Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA for treating cardiovascular disorders. The roles of cytochrome P450 enzymes (CYPs) in the metabolism of STS have remained u...
Authors: Dong-sheng Ouyang, Wei-hua Huang, Dan Chen, Wei Zhang, Zhi-rong Tan, Jing-bo Peng, Yi-cheng Wang, Ying Guo, Dong-li Hu, Jian Xiao and Yao Chen
Ligusticum chuanxiong Hort. (Chuanxiong) is a well-known Chinese medicine, and studies on its chemical constituents are important for explaining its mechanism of action and quality con...
Authors: Jun Yang, Xiao-Lin Feng, Yang Yu, Qi Wang, Jian Zou, Chuan-Xi Wang, Zhen-Qiang Mu, Xin-Sheng Yao and Hao Gao
Calotropis gigantea (Asclepiadaceae) (Niu jiao gua) has been used as a poultice in Chinese medicine for treating inflammatory skin diseases, e.g., neurodermatitis. This study aims to i...
Authors: Supawadee Parhira, Guo-Yuan Zhu, Ting Li, Liang Liu, Li-Ping Bai and Zhi-Hong Jiang
Quantitative real-time reverse transcription PCR (qRT-PCR) requires a stable internal control to avoid misinterpretation of data or errors for gene expression normalization. However, there are still no validat...
Authors: Xin Zhang, Zhi-Chao Xu, Jiang Xu, Ai-Jia Ji, Hong-Mei Luo, Jing-Yuan Song, Chao Sun, Yuan-Lei Hu and Shi-Lin Chen
Radix Salvia miltiorrhiza (Danshen) and Radix Puerariae lobatae (Gegen) are used in Traditional Chinese Medicine to treat cardiovascular diseases. However, adverse herb-drug interactions were observed between war...
Diabetic nephropathy (DN) is a severe micro vascular complication accompanying diabetes mellitus that affects millions of people worldwide. End-stage renal disease occurs in nearly half of all DN patients, res...
Authors: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Stephen Cho-Wing Sze, Yi-Bin Feng, Kai-Fai Lee and Kalin Yan-Bo Zhang
This study aims to identify the major anti-inflammatory components in the petroleum ether extract of Bupleurummalconense (Chaihu), by bioassay-guided fractionation, and to investigate...
Authors: Huai-Xue Mu, Cheng-Yuan Lin, Lin-Fang Huang, Da-Jian Yang, Ai-Ping Lu, Quan-Bin Han and Zhao-Xiang Bian
Chinese medicine (CM) syndrome (zheng) differentiation is based on the co-occurrence of CM manifestation profiles, such as signs and symptoms, and pulse and tongue features. Insomnia is a symptom that frequently ...
Authors: Wing-Fai Yeung, Ka-Fai Chung, Nevin Lian-Wen Zhang, Shi Ping Zhang, Kam-Ping Yung, Pei-Xian Chen and Yan-Yee Ho
While DNA barcoding is an important technology for the authentication of the botanical origins of Chinese medicines, the suitable markers for DNA barcoding of the genus Uncaria have not been reported yet. This st...
Authors: Yin-lin Tang, Yao-sheng Wu, Rui-song Huang, Nai-xia Chao, Yong Liu, Peng Xu, Ke-zhi Li, Dan-zhao Cai and Yu Luo
Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia–Pacific region. In Chinese medicine, HFM...
Cycloartane triterpenoids exhibited anticancer effects. This study aims to identify any potential novel anticancer cycloartane triterpenoids from Cimicifuga foetida L. rhizome (Sheng ma) and the mode of actions.
Authors: Hai-yan Sun, Bei-bei Liu, Jian-yang Hu, Li-jia Xu, Shun-wan Chan, Chi-on Chan, Daniel K. W. Mok, Dong-mei Zhang, Wen-cai Ye and Si-bao Chen
Huangqi decoction (HQD) is used for liver fibrosis and cirrhosis treatment in Chinese medicine. This study aims to investigate the pharmacological actions of HQD against liver fibrosis...
Authors: Gui-biao Zhang, Ya-nan Song, Qi-long Chen, Shu Dong, Yi-yu Lu, Ming-yu Su, Ping Liu and Shi-bing Su
This study aims to analyze the active pharmaceutical ingredients (APIs) of licorice (Radix Glycyrrhizae; gancao), including glycyrrhizic acid, liquiritin, isoliquiritin and total flavonoids, in multi-ingredient a...
Authors: Yang Li, Mingye Guo, Xinyuan Shi, Zhisheng Wu, Jianyu Li, Qun Ma and Yanjiang Qiao
Some isoquinoline alkaloids from Macleaya cordata (Willd). R. Br. (Bo Luo Hui) exhibited antibacterial, antiparasitic, antitumor, and analgesic effects. The targets of these isoquinoline alkaloids are undefined. ...
Authors: Qifang Lei, Haibo Liu, Yong Peng and Peigen Xiao
The outcome of acupuncture on hypertension treatment is inconclusive. This study aims to evaluate the influence of acupuncture on hypertension, based on findings from mechanistic studies over the course of dec...
Authors: Ling Cheng, Peng Li, Stephanie Cheeyee Tjen-A-Looi and John Charles Longhurst
The radix of Glehnia littoralis Fr. Schmidt ex Miq. (Beishashen), is often misidentified and adultered in Chinese medicine. Its seven common adulterants include Chuanminshen violaceum Sheh et Shan (Chuanmingshen)...
The fresh leaves of Eucalyptus globulus Labill. (Lan An) have been used in Chinese medicine for many years to treat dermatomycosis. Macrocarpal C was isolated from this herb and identified as its major antifungal...
Authors: Jack Ho Wong, Kit-Man Lau, Yu-On Wu, Ling Cheng, Chun-Wai Wong, David Tai-Wai Yew, Ping-Chung Leung, Kwok-Pui Fung, Mamie Hui, Tzi-Bun Ng and Clara Bik-San Lau
Deer tendons are believed more effective than cattle tendons in tonifying kidney yang (shen yang) and enhancing bone and tendons. This study aims to differentiate the two types of tendons by a loop-mediated isoth...
Constipation has a high prevalence rate (>30 %) in psychiatric patients with psychotropic drugs. Common pharmacological and non-pharmacological interventions for constipation might have longer-term negative an...
Authors: Wai Kit Wong, Wai Tong Chien and Wai Ming Lee
People seek Chinese medicine (CM) treatments for a variety of respiratory disorders, e.g., asthma and upper respiratory tract infection (URTI). No previous studies have reviewed the data available in medical r...
Authors: Wan Najbah Nik Nabil, Wenyu Zhou, Johannah Linda Shergis, Suzi Mansu, Charlie Changli Xue and Anthony Lin Zhang
Infections such as common colds, influenza, acute upper respiratory infections, bacterial gastroenteritis, and urinary tract infections are usually diagnosed according to patients’ signs and symptoms. This stu...
Authors: Pei-Jung Chiang, Tsai-Chung Li, Chih-Hung Chang, Li-Li Chen, Jun-Dai Lin and Yi-Chang Su
Qing-dai powder (QDP), comprising Indigo naturalis (Qing-dai) and dried alum (Ku-fan), was used in Chinese medicine to treat the conditions associated with mucosal hemorrhage, such as ...
Authors: Hai-Tao Xiao, Jiao Peng, Dong-Dong Hu, Cheng-Yuan Lin, Bin Du, Siu-Wai Tsang, Ze-si Lin, Xiao-Jun Zhang, Feng-Ping Lueng, Quan-Bin Han and Zhao-Xiang Bian
The morphological identification of different Hippophae species (Shaji) was difficult. This study aims to discriminate between medicinal and non-medicinal Hippophae species by DNA barcodes, the ITS2, psbA-trnH, a...
Authors: Yue Liu, Wei Sun, Chuan Liu, Yaqin Zhang, Yilong Chen, Ming Song, Gang Fan, Xia Liu, Li Xiang and Yi Zhang
The combination of a Chinese herbal medicine (CHM) bath and narrowband ultraviolet B (NB-UVB) improved the efficacy of NB-UVB treatment of psoriasis vulgaris, but bath therapy is inconvenient. Oral CHM plus NB...
Authors: Lihong Yang, Claire Shuiqing Zhang, Brian May, Jingjie Yu, Xinfeng Guo, Anthony Lin Zhang, Charlie Changli Xue and Chuanjian Lu
Centipeda minima (Ebushicao) has been used for the treatment of various diseases, such as nasal allergies, rhinitis and sinusitis, nasopharyngeal carcinoma, cough, and headache. This s...
The green speckled lentil seed (Lens culinaris) lectin (GSLL) exhibits hemagglutinating activity, and possesses some properties distinct from those of other lentil lectins (e.g., molecular size, biological activi...
Authors: Yau Sang Chan, Huimin Yu, Lixin Xia and Tzi Bun Ng
Liver-gallbladder dampness-heat (LGDH) and liver kidney yin deficiency (LKYD) syndromes are Chinese medicine (CM) zhengs in chronic hepatitis B (CHB) patients. This study aims to inves...
Authors: Yi-Yu Lu, Yu Zhao, Ya-Nan Song, Shu Dong, Bin Wei, Qi-Long Chen, Yi-Yang Hu and Shi-Bing Su
Ilex latifolia Thunb. (Da Ye Dong Qing) is used for weight loss and for its antidiabetic effects. This study aims to investigate the beneficial effects and potential mechanisms of acti...
Authors: Rui-Bing Feng, Chun-Lin Fan, Qing Liu, Zhong Liu, Wei Zhang, Yao-Lan Li, Wei Tang, Ying Wang, Man-Mei Li and Wen-Cai Ye
DNA barcoding can be used to
authenticate Ganoderma species for safe use. This study aims to identify commercial products containing Ganoderma using DNA barcoding.
Authors: Baosheng Liao, Xiaochen Chen, Jianping Han, Yang Dan, Lili Wang, Wenjing Jiao, Jingyuan Song and Shilin Chen
Postinfectious cough (PIC) significantly affects cough-related quality of life but still lacks effective treatments. This study aims to investigate the efficacy of QingfengGanke granule (QFGKG) in treating PIC in...
Authors: Hongli Jiang, Bing Mao, Lei Wang, Ruiming Zhang, Bin She, Faguang Jin, Yanling Xu, Jian Ma and Qiuping Liu
Anemone flaccida Fr
. Schmidt (Ranunculaceae) (Di Wu in Chinese) is used to treat punch injury and rheumatoid arthritis (RA). However, the active compounds and underlying mechanism of ...
Authors: Qing Liu, Xiu-Zhen Zhu, Rui-Bing Feng, Zhong Liu, Gui-Yang Wang, Xi-Feng Guan, Guo-min Ou, Yao-Lan Li, Ying Wang, Man-Mei Li and Wen-Cai Ye
Erxian decoction (EXD) is used to treat menopause-related symptoms in Chinese medicine. This study aims to identify the bioactive compounds and potential actions of EXD by network phar...
Authors: Shiwei Wang, Yao Tong, Tzi-Bun Ng, Lixing Lao, Jenny Ka Wing Lam, Kalin Yanbo Zhang, Zhang-Jin Zhang and Stephen Cho Wing Sze
This study aims to evaluate the efficacy of Xiaoyaosan (XYS) for treatment of major depressive disorder (MDD) and to review the studies on antidepressant mechanisms of XYS.
Authors: Lin-Lin Jing, Xiao-Xia Zhu, Zhi-Ping Lv and Xue-Gang Sun
