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  1. Although molecular analysis offers a wide range of options for species identification, a universal methodology for classifying and distinguishing closely related species remains elusive. This study validated t...

    Authors: Lan Wu, Mingli Wu, Ning Cui, Li Xiang, Ying Li, Xiwen Li and Shilin Chen

    Citation: Chinese Medicine 2021 16:52

    Content type: Research

    Published on:

  2. The raw and processed roots of Polygonum multiflorum Thunb (PM) are commonly used in clinical practice to treat diverse diseases; however, reports of hepatotoxicity induced by Polygoni Multiflori Radix (PMR) and ...

    Authors: Jian-Bo Yang, Yun-Fei Song, Yue Liu, Hui-Yu Gao, Qi Wang, Ying Wang, Xian-Long Cheng, Tian-Tian Zuo, Xiao-Wen Hu, Feng Wei, Hong-Tao Jin, Shu-Ting Wang and Shuang-Cheng Ma

    Citation: Chinese Medicine 2021 16:51

    Content type: Research

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  3. It is essential to identify the chemical components for the quality control methods establishment of Chinese Classical Formula (CCF). However, CCF are complex mixture of several herbal medicines with huge numb...

    Authors: Xiaoxia Xue, Qishu Jiao, Runa Jin, Xueyuan Wang, Pengyue Li, Shougang Shi, Zhengjun Huang, Yuntao Dai and Shilin Chen

    Citation: Chinese Medicine 2021 16:50

    Content type: Research

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  4. Honeysuckle is a time‐honored herb with anticancer activity in traditional Chinese medicine. Recently, accumulating reports are suggesting that the microRNAs in this medicinal plant not only play a physiologic...

    Authors: Chunyan Liu, Mengzhen Xu, Luocheng Yan, Yulian Wang, Zhen Zhou, Shaocong Wang, Yajie Sun, Junfeng Zhang and Lei Dong

    Citation: Chinese Medicine 2021 16:49

    Content type: Research

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  5. Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge (Danshen), which confers a favorable role in a variety of pharmacological activities including cardiovascular protection. However, the exact m...

    Authors: Youqiong Zhuo, Renyikun Yuan, Xinxin Chen, Jia He, Yangling Chen, Chenwei Zhang, Kaili Sun, Shilin Yang, Zhenjie Liu and Hongwei Gao

    Citation: Chinese Medicine 2021 16:48

    Content type: Research

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  6. Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by memory deficits and cognitive decline. Current drugs can only relieve symptoms, but cannot really cure AD. Cerebralcare Gran...

    Authors: Ou Qiao, Xinyu Zhang, Yi Zhang, Haixia Ji, Zhi Li, Xiaoying Han, Wenzhe Wang, Xia Li, Juan Wang, Changxiao Liu and Wenyuan Gao

    Citation: Chinese Medicine 2021 16:47

    Content type: Research

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  7. Musk, the dried secretion from the musk sac gland which is located between the navel and genitals of mature male musk deer, is utilized as oriental medicine in east Asia. It has been utilized to treat conditio...

    Authors: Kai Liu, Long Xie, Mao Deng, Xumin Zhang, Jia Luo and Xiaofang Li

    Citation: Chinese Medicine 2021 16:46

    Content type: Review

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  8. Panax notoginseng (Burk.) F. H. Chen (P. notoginseng) is a traditional Chinese medicine that has been used therapeutically for cardiovascular diseases, inflammatory diseases and traumatic injuries as well as for ...

    Authors: Li Zhang, Qin Hu, Haonan Jin, Yongzhao Yang, Yan Yang, Renhua Yang, Zhiqiang Shen and Peng Chen

    Citation: Chinese Medicine 2021 16:45

    Content type: Research

    Published on:

  9. The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), first broke out in Wuhan, China, in 2019. SARS-CoV-2 develops many types of mutations (such as B...

    Authors: Xuedong An, Liyun Duan, Yue Hong Zhang, De Jin, Shenghui Zhao, Rong Rong Zhou, Yingying Duan, Fengmei Lian and Xiaolin Tong

    Citation: Chinese Medicine 2021 16:44

    Content type: Review

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  10. Inflammatory bowel diseases (IBD) are chronic relapsing intestinal inflammations with increasing global incidence, and new drug development remains in urgent demand for IBD management. To identify effective tr...

    Authors: Yunru Yu, Jing Chen, Xiaohui Zhang, Yingchao Wang, Shufang Wang, Lu Zhao and Yi Wang

    Citation: Chinese Medicine 2021 16:42

    Content type: Research

    Published on:

  11. Polyphyllin VII (PP7), a steroidal saponin from P. polyphylla has been found to exert strong anticancer activity. Little is known about the anti-angiogenesis and anti-metastasis properties of PP7. In this study, ...

    Authors: Chao Zhang, Qingrui Li, Guozheng Qin, Yi Zhang, Chaoying Li, Liwen Han, Rongchun Wang, Shudan Wang, Haixia Chen, Kechun Liu and Chengwei He

    Citation: Chinese Medicine 2021 16:41

    Content type: Research

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  12. Fritillaria naturally grows in the temperate region of Northern Hemisphere and mainly distributes in Central Asia, Mediterranean region, and North America. The dried bulbs from a dozen species of this genus have ...

    Authors: Ye Wang, Hongping Hou, Qiang Ren, Haoyu Hu, Tiechui Yang and Xiwen Li

    Citation: Chinese Medicine 2021 16:40

    Content type: Review

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  13. Rheumatoid arthritis (RA) is a chronic autoimmune disease. Soufeng sanjie formula (SF), which is composed of scolopendra (dried body of Scolopendra subspinipes mutilans L. Koch), scorpion (dried body of Buthus ma...

    Authors: Di Hua, Jie Yang, Qinghai Meng, Yuanyuan Ling, Qin Wei, Zhigang Wang, Qingyun Wei, Jiao Chen, Juan Ye, Xuan Han, Kelei Su, Weikang Kong, Chao Xu, Peng Cao and Chunping Hu

    Citation: Chinese Medicine 2021 16:39

    Content type: Research

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  14. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhi Xin Li, Guan Ding Zhao, Wei Xiong, Ke Gang Linghu, Qiu Shuo Ma, Wai San Cheang, Hua Yu and Yitao Wang

    Citation: Chinese Medicine 2021 16:38

    Content type: Correction

    Published on:

    The original article was published in Chinese Medicine 2019 14:12

  15. Hua-Zhuo-Jie-Du (HZJD), a Chinese herbal prescription consisting of 11 herbs, is commonly used in China to treat chronic atrophic gastritis (CAG). We aimed to determine the effect of HZJD on the microbiome-a...

    Authors: Pingping Zhou, Xinyu Hao, Yu Liu, Zeqi Yang, Miaochan Xu, Shaowei Liu, Shixiong Zhang, Tianxiao Yang, Xiaomei Wang and Yangang Wang

    Citation: Chinese Medicine 2021 16:37

    Content type: Research

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  16. Complementary remedies such as the Chinese herb ‘Sheng Ma’ (Black cohosh; Actaea racemosa ‘AR’) are being sought to overcome the shortcomings of conventional hormonal and surgical therapies developed for the trea...

    Authors: Asmaa A. Azouz, Sara E. Ali, Reham M. Abd-Elsalam, Shimaa R. Emam, Mona K. Galal, Sherif H. Elmosalamy, Muhammed A. Alsherbiny, Bardes B. Hassan, Chun Guang Li and Shymaa A. El Badawy

    Citation: Chinese Medicine 2021 16:36

    Content type: Research

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  17. Yiganmingmu oral liquid (YGMM), a well known over-the-counter (OTC) drug in China, is composed of 12 types of valuable herbal medicines and has been widely used in clinical for the treatment of soreness and we...

    Authors: Wei Wei, Siwei Li, Linyou Cheng, Erwei Hao, Xiaotao Hou, Hua Zhou, Jiagang Deng and Xinsheng Yao

    Citation: Chinese Medicine 2021 16:35

    Content type: Research

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  18. Guizhi decoction (GZD), a classical Chinese herbal formula, has been widely used to treat hypertension, but its underlying mechanisms remain elusive. The present study aimed to explore the potential mechanisms...

    Authors: Jiye Chen, Yongjian Zhang, Yongcheng Wang, Ping Jiang, Guofeng Zhou, Zhaoyu Li, Jinlong Yang and Xiao Li

    Citation: Chinese Medicine 2021 16:34

    Content type: Research

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  19. Helicobacter pylori (H. pylori) infection has become an international public health problem, and antibiotic-based triple or quadruple therapy is currently the mainstay of treatment. However, the effectiveness of ...

    Authors: Xue Shen, Weijia Zhang, Chang Peng, Jiahui Yan, Pengting Chen, Cheng Jiang, Yuemei Yuan, Donglian Chen, Weixing Zhu and Meicun Yao

    Citation: Chinese Medicine 2021 16:33

    Content type: Research

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  20. Traditional Chinese medicine (TCM) constitution contributes to predicating disease occurrence and pathological progress. In this study, we investigate the correlation between TCM constitution and neurocognitiv...

    Authors: Zhuo Zhang, Yaochen Chuang, Xinyu Ke, Ji Wang, Youhua Xu, Yonghua Zhao and Ying Bian

    Citation: Chinese Medicine 2021 16:32

    Content type: Research

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  21. Rheumatoid arthritis (RA) is a chronic autoimmune disease accompanied with joint destruction that often leads to disability. Wang-Bi capsule (WB), a traditional Chinese medicine-based herbs formula, has exhibi...

    Authors: Haiyang Shu, Hanxiao Zhao, Yingjie Shi, Cheng Lu, Li Li, Ning Zhao, Aiping Lu and Xiaojuan He

    Citation: Chinese Medicine 2021 16:31

    Content type: Research

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  22. Jinqi Jiangtang (JQJT) has been widely used in clinical practice to prevent and treat type 2 diabetes. However, little research has been done to identify and classify its quality markers (Q-markers) associated...

    Authors: Lele Yang, Yan Xue, Jinchao Wei, Qi Dai and Peng Li

    Citation: Chinese Medicine 2021 16:30

    Content type: Research

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  23. Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure, Alzheimer’s disease, and so on. As the typical “hot” traditional Chinese medicin...

    Authors: Juan Liu, Yuzhu Tan, Hui Ao, Wuwen Feng and Cheng Peng

    Citation: Chinese Medicine 2021 16:29

    Content type: Research

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  24. Ginsenoside CK (GCK) serves as the potential anti-colorectal cancer (CRC) protopanaxadiol (PPD)-type saponin, which could be mainly bio-converted to yield PPD by gut microbiota. Meanwhile, the anti-CRC effects...

    Authors: Yin-Ping Guo, Li Shao, Li Wang, Man-Yun Chen, Wei Zhang and Wei-Hua Huang

    Citation: Chinese Medicine 2021 16:28

    Content type: Research

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  25. Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD) for which there is yet any standard pharmacotherapy. Traditional Chinese medicine formula such as Qushihuay...

    Authors: Qingping Lan, Zhitao Ren, Yan Chen, Guozhen Cui, I. Cheong Choi, Carolina Oi Lam Ung, Hon Ho Yu and Simon Ming-Yuen Lee

    Citation: Chinese Medicine 2021 16:27

    Content type: Research

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  26. The Chinese medicinal wine made from herbal medicines became prevalent among Chinese people. The Chinese herbal spirit is composed of several herbal extracts, and has the certain health functions, such as anti...

    Authors: Yan Hu, Zhe Wang, Fangbo Xia, Wen Yang, Yuan-Cai Liu and Jian-Bo Wan

    Citation: Chinese Medicine 2021 16:26

    Content type: Research

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  27. Coronavirus Disease 2019 (COVID-19) is an unprecedented disaster for people around the world. Many studies have shown that traditional Chinese medicine (TCM) are effective in treating COVID-19. However, it is ...

    Authors: Shujie Xia, Zhangfeng Zhong, Bizhen Gao, Chi Teng Vong, Xuejuan Lin, Jin Cai, Hanlu Gao, Ging Chan and Candong Li

    Citation: Chinese Medicine 2021 16:25

    Content type: Research

    Published on:

  28. The National Medical Products Administration (NMPA) in China has set to advance the regulatory capacity of traditional Chinese medicines (TCMs) with the adoption of regulatory science (RS). However, the priori...

    Authors: Zuanji Liang, Yunfeng Lai, Meng Li, Junnan Shi, Chi Ieong Lei, Hao Hu and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:23

    Content type: Review

    Published on:

  29. Galli gigeriae endothelium corneum (GGEC) has been effectively used for centuries for the treatment of functional dyspepsia (FD) in clinical practice in Asian countries. However, its potential mechanism and ch...

    Authors: Shanshan Li, Meng Zheng, Zhentang Zhang, Hengying Peng, Wenling Dai and Jihua Liu

    Citation: Chinese Medicine 2021 16:22

    Content type: Research

    Published on:

  30. Both experimental and clinical studies have revealed satisfactory effects with the traditional Chinese formula Pinggan Qianyang decoction (PGQYD) for improving vascular remodeling caused by essential hypertens...

    Authors: Jiamei Yao, Cui Zhang, Yushu Yang, Xia Fang, Qiong Chen and Guangwei Zhong

    Citation: Chinese Medicine 2021 16:21

    Content type: Research

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  31. The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a compre...

    Authors: Hua Luo, Yi Zhao, Hua Hua, Yan Zhang, Xiaobo Zhang, Qingmao Fang, Qingmiao Li, Yiguan Zhang, Peng Tan, Andong Yang, Shunyuan Jiang, Lanping Guo, Cheng Peng, Yitao Wang, Luqi Huang and Junning Zhao

    Citation: Chinese Medicine 2021 16:19

    Content type: Review

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  32. Shende’an tablet (SDA) is a newly capsuled Chinese herbal formula derived from the Chinese traditional medicine Zhengan Xifeng Decoction which is approved for the treatment of neurasthenia and insomnia in Chin...

    Authors: Xiaoyan Sheng, Shuiyuan Yang, Xiaomin Wen, Xin Zhang, Yongfeng Ye, Peng Zhao, Limin Zang, Kang Peng, Enming Du and Sai Li

    Citation: Chinese Medicine 2021 16:18

    Content type: Research

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  33. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Meng–Huang Wu, Chuang–Yu Lin, Chun–Yin Hou, Ming–Thau Sheu and Hsi Chang

    Citation: Chinese Medicine 2021 16:17

    Content type: Correction

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    The original article was published in Chinese Medicine 2020 15:100

  34. Shikonin (SKO) is a natural naphthoquinone derived from Chinese herbal medicine Arnebiae Radix with high development potentials due to its anti-inflammatory and anti-tumor activities. Overwhelming evidences ha...

    Authors: Anqi Wang, Jiayu Liu, Yuhan Yang, Zhejie Chen, Caifang Gao, Zhanguo Wang, Chaomei Fu, Liang Zou and Shengpeng Wang

    Citation: Chinese Medicine 2021 16:16

    Content type: Research

    Published on:

  35. Hereditary ataxia (HA) represents a group of genetically heterogeneous neurodegenerative diseases caused by dysfunction of the cerebellum or disruption of the connection between the cerebellum and other areas ...

    Authors: Michael Weng Lok Phang, Sze Yuen Lew, Ivy Chung, William Kiong-Seng Lim, Lee Wei Lim and Kah Hui Wong

    Citation: Chinese Medicine 2021 16:15

    Content type: Review

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  36. Suan-Zao-Ren Decoction (SZRD) has been widely used to treat neurological illnesses, including dementia, insomnia and depression. However, the mechanisms underlying SZRD’s improvement in cognitive function rema...

    Authors: Qing-Hua Long, Yong-Gui Wu, Li-Ling He, Li Ding, Ai-Hua Tan, He-Yuan Shi and Ping Wang

    Citation: Chinese Medicine 2021 16:14

    Content type: Research

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  37. Cholangiocarcinoma refers to an epithelial cell malignancy with poor prognosis. Yinchenhao decoction (YCHD) showed positive effects on cancers, and associations between YCHD and cholangiocarcinoma remain uncle...

    Authors: Zhiqiang Chen, Tong Lin, Xiaozhong Liao, Zeyun Li, Ruiting Lin, Xiangjun Qi, Guoming Chen, Lingling Sun and Lizhu Lin

    Citation: Chinese Medicine 2021 16:13

    Content type: Research

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  38. Panax notoginseng triol saponins (PTS) has been used clinically for ischemic stroke therapy (IST) in China for more than 17 years due to its anti-platelet aggregation and neuro-protective effects, but its mech...

    Authors: Zhi-yi Xu, Yang Xu, Xiao-fang Xie, Yin Tian, Jun-hui Sui, Yong Sun, Da-sheng Lin, Xing Gao, Cheng Peng and Yu-jiang Fan

    Citation: Chinese Medicine 2021 16:12

    Content type: Research

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  39. Despite the increased morbidity of ulcerative colitis (UC) in the developing countries, available treatments remain unsatisfactory. Therefore, it is urgent to discover more effective therapeutic strategies. Pulsa...

    Authors: Yong Zhang, Zhengxia Zha, Wenhua Shen, Dan Li, Naixin Kang, Zhong Chen, Yanli Liu, Guoqiang Xu and Qiongming Xu

    Citation: Chinese Medicine 2021 16:11

    Content type: Research

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  40. Electroacupuncture (EA) is generally accepted as a safe and harmless treatment option for alleviating depression. However, there are several challenges related to the use of EA. Although EA has been shown to b...

    Authors: Xuke Han, Yang Gao, Xuan Yin, Zhangjin Zhang, Lixing Lao, Qiu Chen and Shifen Xu

    Citation: Chinese Medicine 2021 16:10

    Content type: Review

    Published on:

    The Correction to this article has been published in Chinese Medicine 2021 16:20

  41. Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that may progress into, in the absence of proper treatment, severe liver damage. While the optimal pharmacotherapy for NAFLD remains uncertai...

    Authors: Zuanji Liang, Xianwen Chen, Junnan Shi, Hao Hu, Yan Xue and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:9

    Content type: Review

    Published on:

  42. Fingerprint analysis and simultaneous multi-components determination are crucial for the holistic quality control of traditional Chinese medicines (TCMs). Yet, reference standards (RS) are often commercially u...

    Authors: Qingjun Wang, Xinlan Yu, Lei Sun, Runtao Tian, Huaizhen He, Sicen Wang and Shuangcheng Ma

    Citation: Chinese Medicine 2021 16:8

    Content type: Research

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  43. Increasing evidence have indicated the relationship between intestinal dysbiosis and hypertension. We aimed to evaluate the effect of the electroacupuncture (EA) on intestinal microbiota in patients with stage...

    Authors: Jun-meng Wang, Ming-xiao Yang, Qiao-feng Wu, Ji Chen, Shu-fang Deng, Lin Chen, Da-neng Wei and Fan-rong Liang

    Citation: Chinese Medicine 2021 16:7

    Content type: Research

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  44. Patchouli (“Guanghuoxiang”) or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In ...

    Authors: Chen Junren, Xie Xiaofang, Li Mengting, Xiong Qiuyun, Li Gangmin, Zhang Huiqiong, Chen Guanru, Xu Xin, Yin Yanpeng, Peng Fu and Peng Cheng

    Citation: Chinese Medicine 2021 16:5

    Content type: Review

    Published on:

  45. Insomnia as one of the dominant diseases of traditional Chinese medicine (TCM) has been extensively studied in recent years. To explore the novel approaches of research on TCM diagnosis and treatment, this pap...

    Authors: Yuqi Tang, Zechen Li, Dongdong Yang, Yu Fang, Shanshan Gao, Shan Liang and Tao Liu

    Citation: Chinese Medicine 2021 16:2

    Content type: Research

    Published on:

  46. The onset of neurodegenerative disease has not only been a major cause of scientific worry, but of economic burden to the health system. This condition has been further attributed to mis-stability, deletion or...

    Authors: Abdullahi Alausa, Sunday Ogundepo, Barakat Olaleke, Rofiat Adeyemi, Mercy Olatinwo and Aminat Ismail

    Citation: Chinese Medicine 2021 16:1

    Content type: Review

    Published on: