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  1. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhi Xin Li, Guan Ding Zhao, Wei Xiong, Ke Gang Linghu, Qiu Shuo Ma, Wai San Cheang, Hua Yu and Yitao Wang

    Citation: Chinese Medicine 2021 16:38

    Content type: Correction

    Published on:

    The original article was published in Chinese Medicine 2019 14:12

  2. Hua-Zhuo-Jie-Du (HZJD), a Chinese herbal prescription consisting of 11 herbs, is commonly used in China to treat chronic atrophic gastritis (CAG). We aimed to determine the effect of HZJD on the microbiome-a...

    Authors: Pingping Zhou, Xinyu Hao, Yu Liu, Zeqi Yang, Miaochan Xu, Shaowei Liu, Shixiong Zhang, Tianxiao Yang, Xiaomei Wang and Yangang Wang

    Citation: Chinese Medicine 2021 16:37

    Content type: Research

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  3. Complementary remedies such as the Chinese herb ‘Sheng Ma’ (Black cohosh; Actaea racemosa ‘AR’) are being sought to overcome the shortcomings of conventional hormonal and surgical therapies developed for the trea...

    Authors: Asmaa A. Azouz, Sara E. Ali, Reham M. Abd-Elsalam, Shimaa R. Emam, Mona K. Galal, Sherif H. Elmosalamy, Muhammed A. Alsherbiny, Bardes B. Hassan, Chun Guang Li and Shymaa A. El Badawy

    Citation: Chinese Medicine 2021 16:36

    Content type: Research

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  4. Yiganmingmu oral liquid (YGMM), a well known over-the-counter (OTC) drug in China, is composed of 12 types of valuable herbal medicines and has been widely used in clinical for the treatment of soreness and we...

    Authors: Wei Wei, Siwei Li, Linyou Cheng, Erwei Hao, Xiaotao Hou, Hua Zhou, Jiagang Deng and Xinsheng Yao

    Citation: Chinese Medicine 2021 16:35

    Content type: Research

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  5. Guizhi decoction (GZD), a classical Chinese herbal formula, has been widely used to treat hypertension, but its underlying mechanisms remain elusive. The present study aimed to explore the potential mechanisms...

    Authors: Jiye Chen, Yongjian Zhang, Yongcheng Wang, Ping Jiang, Guofeng Zhou, Zhaoyu Li, Jinlong Yang and Xiao Li

    Citation: Chinese Medicine 2021 16:34

    Content type: Research

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  6. Helicobacter pylori (H. pylori) infection has become an international public health problem, and antibiotic-based triple or quadruple therapy is currently the mainstay of treatment. However, the effectiveness of ...

    Authors: Xue Shen, Weijia Zhang, Chang Peng, Jiahui Yan, Pengting Chen, Cheng Jiang, Yuemei Yuan, Donglian Chen, Weixing Zhu and Meicun Yao

    Citation: Chinese Medicine 2021 16:33

    Content type: Research

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  7. Traditional Chinese medicine (TCM) constitution contributes to predicating disease occurrence and pathological progress. In this study, we investigate the correlation between TCM constitution and neurocognitiv...

    Authors: Zhuo Zhang, Yaochen Chuang, Xinyu Ke, Ji Wang, Youhua Xu, Yonghua Zhao and Ying Bian

    Citation: Chinese Medicine 2021 16:32

    Content type: Research

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  8. Rheumatoid arthritis (RA) is a chronic autoimmune disease accompanied with joint destruction that often leads to disability. Wang-Bi capsule (WB), a traditional Chinese medicine-based herbs formula, has exhibi...

    Authors: Haiyang Shu, Hanxiao Zhao, Yingjie Shi, Cheng Lu, Li Li, Ning Zhao, Aiping Lu and Xiaojuan He

    Citation: Chinese Medicine 2021 16:31

    Content type: Research

    Published on:

  9. Jinqi Jiangtang (JQJT) has been widely used in clinical practice to prevent and treat type 2 diabetes. However, little research has been done to identify and classify its quality markers (Q-markers) associated...

    Authors: Lele Yang, Yan Xue, Jinchao Wei, Qi Dai and Peng Li

    Citation: Chinese Medicine 2021 16:30

    Content type: Research

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  10. Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure, Alzheimer’s disease, and so on. As the typical “hot” traditional Chinese medicin...

    Authors: Juan Liu, Yuzhu Tan, Hui Ao, Wuwen Feng and Cheng Peng

    Citation: Chinese Medicine 2021 16:29

    Content type: Research

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  11. Ginsenoside CK (GCK) serves as the potential anti-colorectal cancer (CRC) protopanaxadiol (PPD)-type saponin, which could be mainly bio-converted to yield PPD by gut microbiota. Meanwhile, the anti-CRC effects...

    Authors: Yin-Ping Guo, Li Shao, Li Wang, Man-Yun Chen, Wei Zhang and Wei-Hua Huang

    Citation: Chinese Medicine 2021 16:28

    Content type: Research

    Published on:

  12. Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD) for which there is yet any standard pharmacotherapy. Traditional Chinese medicine formula such as Qushihuay...

    Authors: Qingping Lan, Zhitao Ren, Yan Chen, Guozhen Cui, I. Cheong Choi, Carolina Oi Lam Ung, Hon Ho Yu and Simon Ming-Yuen Lee

    Citation: Chinese Medicine 2021 16:27

    Content type: Research

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  13. The Chinese medicinal wine made from herbal medicines became prevalent among Chinese people. The Chinese herbal spirit is composed of several herbal extracts, and has the certain health functions, such as anti...

    Authors: Yan Hu, Zhe Wang, Fangbo Xia, Wen Yang, Yuan-Cai Liu and Jian-Bo Wan

    Citation: Chinese Medicine 2021 16:26

    Content type: Research

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  14. Coronavirus Disease 2019 (COVID-19) is an unprecedented disaster for people around the world. Many studies have shown that traditional Chinese medicine (TCM) are effective in treating COVID-19. However, it is ...

    Authors: Shujie Xia, Zhangfeng Zhong, Bizhen Gao, Chi Teng Vong, Xuejuan Lin, Jin Cai, Hanlu Gao, Ging Chan and Candong Li

    Citation: Chinese Medicine 2021 16:25

    Content type: Research

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  16. The National Medical Products Administration (NMPA) in China has set to advance the regulatory capacity of traditional Chinese medicines (TCMs) with the adoption of regulatory science (RS). However, the priori...

    Authors: Zuanji Liang, Yunfeng Lai, Meng Li, Junnan Shi, Chi Ieong Lei, Hao Hu and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:23

    Content type: Review

    Published on:

  17. Galli gigeriae endothelium corneum (GGEC) has been effectively used for centuries for the treatment of functional dyspepsia (FD) in clinical practice in Asian countries. However, its potential mechanism and ch...

    Authors: Shanshan Li, Meng Zheng, Zhentang Zhang, Hengying Peng, Wenling Dai and Jihua Liu

    Citation: Chinese Medicine 2021 16:22

    Content type: Research

    Published on:

  18. Both experimental and clinical studies have revealed satisfactory effects with the traditional Chinese formula Pinggan Qianyang decoction (PGQYD) for improving vascular remodeling caused by essential hypertens...

    Authors: Jiamei Yao, Cui Zhang, Yushu Yang, Xia Fang, Qiong Chen and Guangwei Zhong

    Citation: Chinese Medicine 2021 16:21

    Content type: Research

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  20. The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a compre...

    Authors: Hua Luo, Yi Zhao, Hua Hua, Yan Zhang, Xiaobo Zhang, Qingmao Fang, Qingmiao Li, Yiguan Zhang, Peng Tan, Andong Yang, Shunyuan Jiang, Lanping Guo, Cheng Peng, Yitao Wang, Luqi Huang and Junning Zhao

    Citation: Chinese Medicine 2021 16:19

    Content type: Review

    Published on:

  21. Shende’an tablet (SDA) is a newly capsuled Chinese herbal formula derived from the Chinese traditional medicine Zhengan Xifeng Decoction which is approved for the treatment of neurasthenia and insomnia in Chin...

    Authors: Xiaoyan Sheng, Shuiyuan Yang, Xiaomin Wen, Xin Zhang, Yongfeng Ye, Peng Zhao, Limin Zang, Kang Peng, Enming Du and Sai Li

    Citation: Chinese Medicine 2021 16:18

    Content type: Research

    Published on:

  22. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Meng–Huang Wu, Chuang–Yu Lin, Chun–Yin Hou, Ming–Thau Sheu and Hsi Chang

    Citation: Chinese Medicine 2021 16:17

    Content type: Correction

    Published on:

    The original article was published in Chinese Medicine 2020 15:100

  23. Shikonin (SKO) is a natural naphthoquinone derived from Chinese herbal medicine Arnebiae Radix with high development potentials due to its anti-inflammatory and anti-tumor activities. Overwhelming evidences ha...

    Authors: Anqi Wang, Jiayu Liu, Yuhan Yang, Zhejie Chen, Caifang Gao, Zhanguo Wang, Chaomei Fu, Liang Zou and Shengpeng Wang

    Citation: Chinese Medicine 2021 16:16

    Content type: Research

    Published on:

  24. Hereditary ataxia (HA) represents a group of genetically heterogeneous neurodegenerative diseases caused by dysfunction of the cerebellum or disruption of the connection between the cerebellum and other areas ...

    Authors: Michael Weng Lok Phang, Sze Yuen Lew, Ivy Chung, William Kiong-Seng Lim, Lee Wei Lim and Kah Hui Wong

    Citation: Chinese Medicine 2021 16:15

    Content type: Review

    Published on:

  25. Suan-Zao-Ren Decoction (SZRD) has been widely used to treat neurological illnesses, including dementia, insomnia and depression. However, the mechanisms underlying SZRD’s improvement in cognitive function rema...

    Authors: Qing-Hua Long, Yong-Gui Wu, Li-Ling He, Li Ding, Ai-Hua Tan, He-Yuan Shi and Ping Wang

    Citation: Chinese Medicine 2021 16:14

    Content type: Research

    Published on:

  26. Cholangiocarcinoma refers to an epithelial cell malignancy with poor prognosis. Yinchenhao decoction (YCHD) showed positive effects on cancers, and associations between YCHD and cholangiocarcinoma remain uncle...

    Authors: Zhiqiang Chen, Tong Lin, Xiaozhong Liao, Zeyun Li, Ruiting Lin, Xiangjun Qi, Guoming Chen, Lingling Sun and Lizhu Lin

    Citation: Chinese Medicine 2021 16:13

    Content type: Research

    Published on:

  27. Panax notoginseng triol saponins (PTS) has been used clinically for ischemic stroke therapy (IST) in China for more than 17 years due to its anti-platelet aggregation and neuro-protective effects, but its mech...

    Authors: Zhi-yi Xu, Yang Xu, Xiao-fang Xie, Yin Tian, Jun-hui Sui, Yong Sun, Da-sheng Lin, Xing Gao, Cheng Peng and Yu-jiang Fan

    Citation: Chinese Medicine 2021 16:12

    Content type: Research

    Published on:

  28. Despite the increased morbidity of ulcerative colitis (UC) in the developing countries, available treatments remain unsatisfactory. Therefore, it is urgent to discover more effective therapeutic strategies. Pulsa...

    Authors: Yong Zhang, Zhengxia Zha, Wenhua Shen, Dan Li, Naixin Kang, Zhong Chen, Yanli Liu, Guoqiang Xu and Qiongming Xu

    Citation: Chinese Medicine 2021 16:11

    Content type: Research

    Published on:

  29. Electroacupuncture (EA) is generally accepted as a safe and harmless treatment option for alleviating depression. However, there are several challenges related to the use of EA. Although EA has been shown to b...

    Authors: Xuke Han, Yang Gao, Xuan Yin, Zhangjin Zhang, Lixing Lao, Qiu Chen and Shifen Xu

    Citation: Chinese Medicine 2021 16:10

    Content type: Review

    Published on:

    The Correction to this article has been published in Chinese Medicine 2021 16:20

  30. Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that may progress into, in the absence of proper treatment, severe liver damage. While the optimal pharmacotherapy for NAFLD remains uncertai...

    Authors: Zuanji Liang, Xianwen Chen, Junnan Shi, Hao Hu, Yan Xue and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:9

    Content type: Review

    Published on:

  31. Fingerprint analysis and simultaneous multi-components determination are crucial for the holistic quality control of traditional Chinese medicines (TCMs). Yet, reference standards (RS) are often commercially u...

    Authors: Qingjun Wang, Xinlan Yu, Lei Sun, Runtao Tian, Huaizhen He, Sicen Wang and Shuangcheng Ma

    Citation: Chinese Medicine 2021 16:8

    Content type: Research

    Published on:

  32. Increasing evidence have indicated the relationship between intestinal dysbiosis and hypertension. We aimed to evaluate the effect of the electroacupuncture (EA) on intestinal microbiota in patients with stage...

    Authors: Jun-meng Wang, Ming-xiao Yang, Qiao-feng Wu, Ji Chen, Shu-fang Deng, Lin Chen, Da-neng Wei and Fan-rong Liang

    Citation: Chinese Medicine 2021 16:7

    Content type: Research

    Published on:

  34. Patchouli (“Guanghuoxiang”) or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In ...

    Authors: Chen Junren, Xie Xiaofang, Li Mengting, Xiong Qiuyun, Li Gangmin, Zhang Huiqiong, Chen Guanru, Xu Xin, Yin Yanpeng, Peng Fu and Peng Cheng

    Citation: Chinese Medicine 2021 16:5

    Content type: Review

    Published on:

  35. To investigate the microRNA (miRNA)-gene interactions underlying leukocyte functions and characteristics, especially the potential serum biomarkers, implicated in the traditional Chinese medicine (TCM)-defined...

    Authors: Leiming You, Shen Zhang, Ting’an Li, Xiaopu Sang, Kunyu Li, Wei Wang, Xinhui Gao, Jiarui Wu, Guangrui Huang, Ting Wang and Anlong Xu

    Citation: Chinese Medicine 2021 16:4

    Content type: Research

    Published on:

  36. OPD and OPD' are the two main active components of Ophiopogon japonicas in Shenmai injection (SMI). Being isomers of each other, they are supposed to have similar pharmacological activities, but the actual sit...

    Authors: Huan-Hua Xu, Zhen-Hong Jiang, Cong-Shu Huang, Yu-Ting Sun, Long-Long Xu, Xiang-Ling Tang, Hong-Ling Tan, Zeng-Chun Ma and Yue Gao

    Citation: Chinese Medicine 2021 16:3

    Content type: Research

    Published on:

  37. Insomnia as one of the dominant diseases of traditional Chinese medicine (TCM) has been extensively studied in recent years. To explore the novel approaches of research on TCM diagnosis and treatment, this pap...

    Authors: Yuqi Tang, Zechen Li, Dongdong Yang, Yu Fang, Shanshan Gao, Shan Liang and Tao Liu

    Citation: Chinese Medicine 2021 16:2

    Content type: Research

    Published on:

  38. The onset of neurodegenerative disease has not only been a major cause of scientific worry, but of economic burden to the health system. This condition has been further attributed to mis-stability, deletion or...

    Authors: Abdullahi Alausa, Sunday Ogundepo, Barakat Olaleke, Rofiat Adeyemi, Mercy Olatinwo and Aminat Ismail

    Citation: Chinese Medicine 2021 16:1

    Content type: Review

    Published on:

  39. Infections induced by influenza viruses, as well as coronavirus disease 19 (COVID-19) pandemic induced by severe acute respiratory coronavirus 2 (SARS-CoV-2) led to acute lung injury (ALI) and multi organ fail...

    Authors: Peng Tu, Rong Tian, Yan Lu, Yunyi Zhang, Haiyan Zhu, Lijun Ling, Hong Li and Daofeng Chen

    Citation: Chinese Medicine 2020 15:128

    Content type: Research

    Published on:

  40. Indigo naturalis is a blue dye in ancient, as well as an extensive used traditional Chinese medicine. It has a wide spectrum of pharmacological properties and can be used to treat numerous ailments such as leu...

    Authors: Yang Qi-yue, Zhang Ting, He Ya-nan, Huang Sheng-jie, Deng Xuan, Han Li and Xie Chun-guang

    Citation: Chinese Medicine 2020 15:127

    Content type: Review

    Published on:

  44. Autophagy is a highly conserved degradation process for long-lived intracellular proteins and organelles mediated by lysosomes. Deficits in the autophagy-lysosome pathway (ALP) have been linked to a variety of...

    Authors: Jie Xu, Xiao-Qi Zhang and Zaijun Zhang

    Citation: Chinese Medicine 2020 15:123

    Content type: Review

    Published on:

  45. Liver ischemia/reperfusion (I/R) injury is an inevitable pathological phenomenon in various clinical conditions, such as liver transplantation, resection surgery, or shock, which is the major cause of morbidit...

    Authors: Zheng Wang, Ping Zhang, Qingqing Wang, Xueping Sheng, Jianbing Zhang, Xiaoyan Lu and Xiaohui Fan

    Citation: Chinese Medicine 2020 15:122

    Content type: Research

    Published on:

  46. Diabetes is a complex metabolic disease characterized by hyperglycemia, plaguing the whole world. However, the action mode of multi-component and multi-target for traditional Chinese medicine (TCM) could be a ...

    Authors: Yunfei Song, Jianbo Yang, Wenguang Jing, Qi Wang, Yue Liu, Xianlong Cheng, Fei Ye, Jinying Tian, Feng Wei and Shuangcheng Ma

    Citation: Chinese Medicine 2020 15:121

    Content type: Research

    Published on:

  47. This study was aimed to investigate the therapeutic effects and potential mechanism of higenamine combined with [6]-gingerol (HG/[6]-GR) against doxorubicin (DOX)—induced chronic heart failure (CHF) in rats.

    Authors: Jianxia Wen, Xiao Ma, Ming Niu, Junjie Hao, Ying Huang, Ruilin Wang, Ruisheng Li, Jian Wang and Yanling Zhao

    Citation: Chinese Medicine 2020 15:120

    Content type: Research

    Published on:

  48. Naoshuantong capsule (NSTC) is an oral Chinese medicine formula composed of Typhae Pollen, Radix Paeoniae Rubra, Curcumae Radix, Gastrodiae Rhizoma and Radix Rhapontici. It has been widely used at the acute an...

    Authors: Lvkeng Luo, Shuling Wu, Ruiqi Chen, Hongyu Rao, Wei Peng and Weiwei Su

    Citation: Chinese Medicine 2020 15:119

    Content type: Research

    Published on:

  49. Cancer cells through autophagy-mediated recycling to meet the metabolic demands of growth and proliferation. The steroidal saponin 20(S)-ginsenoside Rh2 effectively inhibits the growth and survival of a variet...

    Authors: Jiawen Wang, Shuai Bian, Siming Wang, Song Yang, Wanying Zhang, Daqing Zhao, Meichen Liu and Xueyuan Bai

    Citation: Chinese Medicine 2020 15:118

    Content type: Research

    Published on:

  50. The use of anti-inflammatory and analgesic drugs such as nonsteroidal anti-inflammatory drugs(NSAIDs) for treating acute gout has limitations, such as adverse reactions in the gastrointestinal tract and toxici...

    Authors: Shuang Ren, Fanyan Meng, Yantong Liu, Yun Meng, Ning Tao, Ruoshi Liu and Jie Zhang

    Citation: Chinese Medicine 2020 15:117

    Content type: Research

    Published on:

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ISSN: 1749-8546

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