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  1. Exaggerated immune response and cytokine storm are accounted for the severity of COVID-19, including organ dysfunction, especially progressive respiratory failure and generalized coagulopathy. Uncontrolled act...

    Authors: Yadong Fan, Ying Wang, Shuang Yu, Jun Chang, Yiqi Yan, Yiyang Wang and Yuhong Bian

    Citation: Chinese Medicine 2021 16:67

    Content type: Review

    Published on:

  2. Idiopathic pulmonary fibrosis (IPF) is a serious chronic disease of the respiratory system, but its current treatment has certain shortcomings and adverse effects. In this study, we evaluate the antifibrotic a...

    Authors: Yanfang Peng, Yingwen Zhang, Yabing Zhang, Xiuping Wang and Yukun Xia

    Citation: Chinese Medicine 2021 16:66

    Content type: Research

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  3. Synaptic damage and glutamate excitotoxicity have been implicated in the pathogenesis of vascular dementia (VD). Clathrin, RAB5B and N-methyl-d-aspartic acid receptor 1 (NMDAR1) proteins play a vital role in endo...

    Authors: Danfeng Tian, Yangyang Guo, Dandan Zhang, Qiang Gao, Ganlu Liu, Jingfeng Lin, Ze Chang, Yuchun Wang, Rui Su and Zhenyun Han

    Citation: Chinese Medicine 2021 16:65

    Content type: Research

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  4. To assess the reporting quality of randomised controlled trials (RCTs) of massage, particularly whether necessary elements related to massage interventions were adequately reported.

    Authors: Xuan Zhang, Lin Zhang, Weifeng Xiong, Xihong Wang, Xiaohan Zhou, Chen Zhao, Guihua Tian, Hongcai Shang, Taixiang Wu, Jiangxia Miao and Zhaoxiang Bian

    Citation: Chinese Medicine 2021 16:64

    Content type: Research

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  5. The worldwide prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing, and this metabolic disorder has been recognized as a severe threat to human health. A variety of chemical drugs have been app...

    Authors: Xiao-Fang Yang, Ming Lu, Lijiao You, Huan Gen, Lin Yuan, Tianning Tian, Chun-Yu Li, Kailiang Xu, Jie Hou and Ming Lei

    Citation: Chinese Medicine 2021 16:62

    Content type: Review

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  6. Panax notoginseng saponins (PNS) as the main effective substances from P. notoginseng with low bioavailability could be bio-converted by human gut microbiota. In our previous study, PNS metabolic variations media...

    Authors: Li Wang, Man-Yun Chen, Li Shao, Wei Zhang, Xiang-Ping Li and Wei-Hua Huang

    Citation: Chinese Medicine 2021 16:60

    Content type: Research

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  7. The traditional Chinese medicine Huangqi decoction (HQD) consists of Radix Astragali and Radix Glycyrrhizae in a ratio of 6: 1, which has been used for the treatment of liver fibrosis. In this study, we tried to ...

    Authors: Biting Wang, Zengrui Wu, Weihua Li, Guixia Liu and Yun Tang

    Citation: Chinese Medicine 2021 16:59

    Content type: Research

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  8. Corydalis saxicola Bunting, affiliated with the Papaveraceae Juss., has been proven to work well in anti-inflammation, hemostasis, and analgesia. This study was designed to observe the effect and potential mechan...

    Authors: Chu Xue, Si-Xue Liu, Jie Hu, Jin Huang, Hong-Min Liu, Zhi-Xia Qiu and Fang Huang

    Citation: Chinese Medicine 2021 16:58

    Content type: Research

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  9. The desire to extend the wisdom of traditional health systems has motivated the trade of many phytomedicine on a global scale for centuries, especially some dietary herbs, making a great overlap exits between ...

    Authors: Xiuzhu Li, Weijie Chen, Jesus Simal-Gandara, Milen I. Georgiev, Hongyi Li, Hao Hu, Xu Wu, Thomas Efferth and Shengpeng Wang

    Citation: Chinese Medicine 2021 16:57

    Content type: Review

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  10. Acupuncture is used in the treatment of a variety of inflammatory conditions and diseases. However, the mechanisms of its anti-inflammatory action are complex and have not been systematically investigated. Mac...

    Authors: Jiaqi Wang, Shanshan Lu, Fuming Yang, Yi Guo, Zelin Chen, Nannan Yu, Lin Yao, Jin Huang, Wen Fan, Zhifang Xu and Yinan Gong

    Citation: Chinese Medicine 2021 16:56

    Content type: Review

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  11. The pathological process of myocardial ischemia (MI) is very complicated. Acupuncture at PC6 has been proved to be effective against MI injury, but the mechanism remains unclear. This study investigated the me...

    Authors: Jing Yuan, Jun-Meng Wang, Zhi-Wei Li, Cheng-Shun Zhang, Bin Cheng, Su-Hao Yang, Bai-Tong Liu, Li-Juan Zhu, Ding-Jun Cai and Shu-Guang Yu

    Citation: Chinese Medicine 2021 16:55

    Content type: Research

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  12. Hypertension (HTN) patients who have phlegm-dampness syndrome (PDS) tend to be obese and have worse outcomes. However, the association of body weight (BW) changes and mechanisms underlying the pathophysiology ...

    Authors: Chi Zhang, Li Li, Shiping Cheng, Debajyoti Chowdhury, Yong Tan, Xinru Liu, Ning Zhao, Xiaojuan He, Miao Jiang, Cheng Lu and Aiping Lyu

    Citation: Chinese Medicine 2021 16:54

    Content type: Research

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  13. Although molecular analysis offers a wide range of options for species identification, a universal methodology for classifying and distinguishing closely related species remains elusive. This study validated t...

    Authors: Lan Wu, Mingli Wu, Ning Cui, Li Xiang, Ying Li, Xiwen Li and Shilin Chen

    Citation: Chinese Medicine 2021 16:52

    Content type: Research

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  14. The raw and processed roots of Polygonum multiflorum Thunb (PM) are commonly used in clinical practice to treat diverse diseases; however, reports of hepatotoxicity induced by Polygoni Multiflori Radix (PMR) and ...

    Authors: Jian-Bo Yang, Yun-Fei Song, Yue Liu, Hui-Yu Gao, Qi Wang, Ying Wang, Xian-Long Cheng, Tian-Tian Zuo, Xiao-Wen Hu, Feng Wei, Hong-Tao Jin, Shu-Ting Wang and Shuang-Cheng Ma

    Citation: Chinese Medicine 2021 16:51

    Content type: Research

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  15. It is essential to identify the chemical components for the quality control methods establishment of Chinese Classical Formula (CCF). However, CCF are complex mixture of several herbal medicines with huge numb...

    Authors: Xiaoxia Xue, Qishu Jiao, Runa Jin, Xueyuan Wang, Pengyue Li, Shougang Shi, Zhengjun Huang, Yuntao Dai and Shilin Chen

    Citation: Chinese Medicine 2021 16:50

    Content type: Research

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  16. Honeysuckle is a time‐honored herb with anticancer activity in traditional Chinese medicine. Recently, accumulating reports are suggesting that the microRNAs in this medicinal plant not only play a physiologic...

    Authors: Chunyan Liu, Mengzhen Xu, Luocheng Yan, Yulian Wang, Zhen Zhou, Shaocong Wang, Yajie Sun, Junfeng Zhang and Lei Dong

    Citation: Chinese Medicine 2021 16:49

    Content type: Research

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  17. Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge (Danshen), which confers a favorable role in a variety of pharmacological activities including cardiovascular protection. However, the exact m...

    Authors: Youqiong Zhuo, Renyikun Yuan, Xinxin Chen, Jia He, Yangling Chen, Chenwei Zhang, Kaili Sun, Shilin Yang, Zhenjie Liu and Hongwei Gao

    Citation: Chinese Medicine 2021 16:48

    Content type: Research

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  18. Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by memory deficits and cognitive decline. Current drugs can only relieve symptoms, but cannot really cure AD. Cerebralcare Gran...

    Authors: Ou Qiao, Xinyu Zhang, Yi Zhang, Haixia Ji, Zhi Li, Xiaoying Han, Wenzhe Wang, Xia Li, Juan Wang, Changxiao Liu and Wenyuan Gao

    Citation: Chinese Medicine 2021 16:47

    Content type: Research

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  19. Musk, the dried secretion from the musk sac gland which is located between the navel and genitals of mature male musk deer, is utilized as oriental medicine in east Asia. It has been utilized to treat conditio...

    Authors: Kai Liu, Long Xie, Mao Deng, Xumin Zhang, Jia Luo and Xiaofang Li

    Citation: Chinese Medicine 2021 16:46

    Content type: Review

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  20. Panax notoginseng (Burk.) F. H. Chen (P. notoginseng) is a traditional Chinese medicine that has been used therapeutically for cardiovascular diseases, inflammatory diseases and traumatic injuries as well as for ...

    Authors: Li Zhang, Qin Hu, Haonan Jin, Yongzhao Yang, Yan Yang, Renhua Yang, Zhiqiang Shen and Peng Chen

    Citation: Chinese Medicine 2021 16:45

    Content type: Research

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  21. The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), first broke out in Wuhan, China, in 2019. SARS-CoV-2 develops many types of mutations (such as B...

    Authors: Xuedong An, Liyun Duan, Yue Hong Zhang, De Jin, Shenghui Zhao, Rong Rong Zhou, Yingying Duan, Fengmei Lian and Xiaolin Tong

    Citation: Chinese Medicine 2021 16:44

    Content type: Review

    Published on:

  22. Inflammatory bowel diseases (IBD) are chronic relapsing intestinal inflammations with increasing global incidence, and new drug development remains in urgent demand for IBD management. To identify effective tr...

    Authors: Yunru Yu, Jing Chen, Xiaohui Zhang, Yingchao Wang, Shufang Wang, Lu Zhao and Yi Wang

    Citation: Chinese Medicine 2021 16:42

    Content type: Research

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  23. Polyphyllin VII (PP7), a steroidal saponin from P. polyphylla has been found to exert strong anticancer activity. Little is known about the anti-angiogenesis and anti-metastasis properties of PP7. In this study, ...

    Authors: Chao Zhang, Qingrui Li, Guozheng Qin, Yi Zhang, Chaoying Li, Liwen Han, Rongchun Wang, Shudan Wang, Haixia Chen, Kechun Liu and Chengwei He

    Citation: Chinese Medicine 2021 16:41

    Content type: Research

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  24. Fritillaria naturally grows in the temperate region of Northern Hemisphere and mainly distributes in Central Asia, Mediterranean region, and North America. The dried bulbs from a dozen species of this genus have ...

    Authors: Ye Wang, Hongping Hou, Qiang Ren, Haoyu Hu, Tiechui Yang and Xiwen Li

    Citation: Chinese Medicine 2021 16:40

    Content type: Review

    Published on:

  25. Rheumatoid arthritis (RA) is a chronic autoimmune disease. Soufeng sanjie formula (SF), which is composed of scolopendra (dried body of Scolopendra subspinipes mutilans L. Koch), scorpion (dried body of Buthus ma...

    Authors: Di Hua, Jie Yang, Qinghai Meng, Yuanyuan Ling, Qin Wei, Zhigang Wang, Qingyun Wei, Jiao Chen, Juan Ye, Xuan Han, Kelei Su, Weikang Kong, Chao Xu, Peng Cao and Chunping Hu

    Citation: Chinese Medicine 2021 16:39

    Content type: Research

    Published on:

  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhi Xin Li, Guan Ding Zhao, Wei Xiong, Ke Gang Linghu, Qiu Shuo Ma, Wai San Cheang, Hua Yu and Yitao Wang

    Citation: Chinese Medicine 2021 16:38

    Content type: Correction

    Published on:

    The original article was published in Chinese Medicine 2019 14:12

  27. Hua-Zhuo-Jie-Du (HZJD), a Chinese herbal prescription consisting of 11 herbs, is commonly used in China to treat chronic atrophic gastritis (CAG). We aimed to determine the effect of HZJD on the microbiome-a...

    Authors: Pingping Zhou, Xinyu Hao, Yu Liu, Zeqi Yang, Miaochan Xu, Shaowei Liu, Shixiong Zhang, Tianxiao Yang, Xiaomei Wang and Yangang Wang

    Citation: Chinese Medicine 2021 16:37

    Content type: Research

    Published on:

  28. Complementary remedies such as the Chinese herb ‘Sheng Ma’ (Black cohosh; Actaea racemosa ‘AR’) are being sought to overcome the shortcomings of conventional hormonal and surgical therapies developed for the trea...

    Authors: Asmaa A. Azouz, Sara E. Ali, Reham M. Abd-Elsalam, Shimaa R. Emam, Mona K. Galal, Sherif H. Elmosalamy, Muhammed A. Alsherbiny, Bardes B. Hassan, Chun Guang Li and Shymaa A. El Badawy

    Citation: Chinese Medicine 2021 16:36

    Content type: Research

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  29. Yiganmingmu oral liquid (YGMM), a well known over-the-counter (OTC) drug in China, is composed of 12 types of valuable herbal medicines and has been widely used in clinical for the treatment of soreness and we...

    Authors: Wei Wei, Siwei Li, Linyou Cheng, Erwei Hao, Xiaotao Hou, Hua Zhou, Jiagang Deng and Xinsheng Yao

    Citation: Chinese Medicine 2021 16:35

    Content type: Research

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  30. Guizhi decoction (GZD), a classical Chinese herbal formula, has been widely used to treat hypertension, but its underlying mechanisms remain elusive. The present study aimed to explore the potential mechanisms...

    Authors: Jiye Chen, Yongjian Zhang, Yongcheng Wang, Ping Jiang, Guofeng Zhou, Zhaoyu Li, Jinlong Yang and Xiao Li

    Citation: Chinese Medicine 2021 16:34

    Content type: Research

    Published on:

  31. Helicobacter pylori (H. pylori) infection has become an international public health problem, and antibiotic-based triple or quadruple therapy is currently the mainstay of treatment. However, the effectiveness of ...

    Authors: Xue Shen, Weijia Zhang, Chang Peng, Jiahui Yan, Pengting Chen, Cheng Jiang, Yuemei Yuan, Donglian Chen, Weixing Zhu and Meicun Yao

    Citation: Chinese Medicine 2021 16:33

    Content type: Research

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  32. Traditional Chinese medicine (TCM) constitution contributes to predicating disease occurrence and pathological progress. In this study, we investigate the correlation between TCM constitution and neurocognitiv...

    Authors: Zhuo Zhang, Yaochen Chuang, Xinyu Ke, Ji Wang, Youhua Xu, Yonghua Zhao and Ying Bian

    Citation: Chinese Medicine 2021 16:32

    Content type: Research

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  33. Rheumatoid arthritis (RA) is a chronic autoimmune disease accompanied with joint destruction that often leads to disability. Wang-Bi capsule (WB), a traditional Chinese medicine-based herbs formula, has exhibi...

    Authors: Haiyang Shu, Hanxiao Zhao, Yingjie Shi, Cheng Lu, Li Li, Ning Zhao, Aiping Lu and Xiaojuan He

    Citation: Chinese Medicine 2021 16:31

    Content type: Research

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  34. Jinqi Jiangtang (JQJT) has been widely used in clinical practice to prevent and treat type 2 diabetes. However, little research has been done to identify and classify its quality markers (Q-markers) associated...

    Authors: Lele Yang, Yan Xue, Jinchao Wei, Qi Dai and Peng Li

    Citation: Chinese Medicine 2021 16:30

    Content type: Research

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  35. Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure, Alzheimer’s disease, and so on. As the typical “hot” traditional Chinese medicin...

    Authors: Juan Liu, Yuzhu Tan, Hui Ao, Wuwen Feng and Cheng Peng

    Citation: Chinese Medicine 2021 16:29

    Content type: Research

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  36. Ginsenoside CK (GCK) serves as the potential anti-colorectal cancer (CRC) protopanaxadiol (PPD)-type saponin, which could be mainly bio-converted to yield PPD by gut microbiota. Meanwhile, the anti-CRC effects...

    Authors: Yin-Ping Guo, Li Shao, Li Wang, Man-Yun Chen, Wei Zhang and Wei-Hua Huang

    Citation: Chinese Medicine 2021 16:28

    Content type: Research

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  37. Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD) for which there is yet any standard pharmacotherapy. Traditional Chinese medicine formula such as Qushihuay...

    Authors: Qingping Lan, Zhitao Ren, Yan Chen, Guozhen Cui, I. Cheong Choi, Carolina Oi Lam Ung, Hon Ho Yu and Simon Ming-Yuen Lee

    Citation: Chinese Medicine 2021 16:27

    Content type: Research

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  38. The Chinese medicinal wine made from herbal medicines became prevalent among Chinese people. The Chinese herbal spirit is composed of several herbal extracts, and has the certain health functions, such as anti...

    Authors: Yan Hu, Zhe Wang, Fangbo Xia, Wen Yang, Yuan-Cai Liu and Jian-Bo Wan

    Citation: Chinese Medicine 2021 16:26

    Content type: Research

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  39. Coronavirus Disease 2019 (COVID-19) is an unprecedented disaster for people around the world. Many studies have shown that traditional Chinese medicine (TCM) are effective in treating COVID-19. However, it is ...

    Authors: Shujie Xia, Zhangfeng Zhong, Bizhen Gao, Chi Teng Vong, Xuejuan Lin, Jin Cai, Hanlu Gao, Ging Chan and Candong Li

    Citation: Chinese Medicine 2021 16:25

    Content type: Research

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  40. The National Medical Products Administration (NMPA) in China has set to advance the regulatory capacity of traditional Chinese medicines (TCMs) with the adoption of regulatory science (RS). However, the priori...

    Authors: Zuanji Liang, Yunfeng Lai, Meng Li, Junnan Shi, Chi Ieong Lei, Hao Hu and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2021 16:23

    Content type: Review

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  41. Galli gigeriae endothelium corneum (GGEC) has been effectively used for centuries for the treatment of functional dyspepsia (FD) in clinical practice in Asian countries. However, its potential mechanism and ch...

    Authors: Shanshan Li, Meng Zheng, Zhentang Zhang, Hengying Peng, Wenling Dai and Jihua Liu

    Citation: Chinese Medicine 2021 16:22

    Content type: Research

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  42. Both experimental and clinical studies have revealed satisfactory effects with the traditional Chinese formula Pinggan Qianyang decoction (PGQYD) for improving vascular remodeling caused by essential hypertens...

    Authors: Jiamei Yao, Cui Zhang, Yushu Yang, Xia Fang, Qiong Chen and Guangwei Zhong

    Citation: Chinese Medicine 2021 16:21

    Content type: Research

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  43. The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a compre...

    Authors: Hua Luo, Yi Zhao, Hua Hua, Yan Zhang, Xiaobo Zhang, Qingmao Fang, Qingmiao Li, Yiguan Zhang, Peng Tan, Andong Yang, Shunyuan Jiang, Lanping Guo, Cheng Peng, Yitao Wang, Luqi Huang and Junning Zhao

    Citation: Chinese Medicine 2021 16:19

    Content type: Review

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  44. Shende’an tablet (SDA) is a newly capsuled Chinese herbal formula derived from the Chinese traditional medicine Zhengan Xifeng Decoction which is approved for the treatment of neurasthenia and insomnia in Chin...

    Authors: Xiaoyan Sheng, Shuiyuan Yang, Xiaomin Wen, Xin Zhang, Yongfeng Ye, Peng Zhao, Limin Zang, Kang Peng, Enming Du and Sai Li

    Citation: Chinese Medicine 2021 16:18

    Content type: Research

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