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  1. Infantile colic is a common painful clinical condition associated with signs of distended intestines and an increase in colon peristalsis. However, clinical documentation of observed gastrointestinal functions...

    Authors: Marianne Reinthal, Iréne Lund, Dacil Ullman and Thomas Lundeberg

    Citation: Chinese Medicine 2011 6:28

    Content type: Research

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  2. In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiti...

    Authors: Wen Tan, Jinjian Lu, Mingqing Huang, Yingbo Li, Meiwan Chen, Guosheng Wu, Jian Gong, Zhangfeng Zhong, Zengtao Xu, Yuanye Dang, Jiajie Guo, Xiuping Chen and Yitao Wang

    Citation: Chinese Medicine 2011 6:27

    Content type: Review

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  3. Since oxidative stress has been implicated in a neurodegenerative disease such as Alzheimer's disease (AD), natural antioxidants are promising candidates of chemopreventive agents. This study examines antioxid...

    Authors: Chang-Ho Jeong, Hee Rok Jeong, Gwi Nam Choi, Dae-Ok Kim, Uk Lee and Ho Jin Heo

    Citation: Chinese Medicine 2011 6:25

    Content type: Research

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  4. While evidence supports efficacy of acupuncture and/or dry needling in treating musculoskeletal pain, it is unclear which needling method is most effective. This study aims to determine the effects of depth of...

    Authors: Kazunori Itoh, Yoichi Minakawa and Hiroshi Kitakoji

    Citation: Chinese Medicine 2011 6:24

    Content type: Research

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  5. Hypertension is a clinical condition that manifests target-organ damage (TOD) with symptoms. This study investigates the association between Zangfu patterns and symptomatic manifestations of TOD.

    Authors: Alexandre Bastos Luiz, Ivan Cordovil, José Barbosa Filho and Arthur Sá Ferreira

    Citation: Chinese Medicine 2011 6:23

    Content type: Research

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  6. Immuno-modulatory effects of ginseng, including both immuno-stimulatory and immuno-suppressive effects, have been widely reported. This study aims to determine whether the paradoxical immuno-modulatory effect ...

    Authors: Chike Godwin Azike, Paul Abrahams Charpentier, Jirui Hou, Hua Pei and Edmund Man King Lui

    Citation: Chinese Medicine 2011 6:21

    Content type: Research

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  7. Oleanolic acid (OA) is a natural triterpenoid possessing anti-inflammatory, antitumor, antiviral, hepatoprotective and antihyperlipidemic effects. Research on the pharmacological activities and clinical applic...

    Authors: Meiwan Chen, Zhangfeng Zhong, Wen Tan, Shengpeng Wang and Yitao Wang

    Citation: Chinese Medicine 2011 6:20

    Content type: Review

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  8. The present study investigates the effects of ginsenosides Rh1 and Rg2 against 6-hydroxydopamine (6-OHDA), a neurotoxin on SH-SY5Y cells and PC-12 cells. The effects of these two ginsenosides on neuronal differen...

    Authors: Xiao-Fan Li, Cathy Nga-Ping Lui, Zhi-Hong Jiang and Yung Kin-Lam Ken

    Citation: Chinese Medicine 2011 6:19

    Content type: Research

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  9. Poor quality control of medicinal herbs has led to instances of toxicity, poisoning and even deaths. The fundamental step in quality control of herbal medicine is accurate identification of herbs. Array-based ...

    Authors: Linhai Niu, Nitin Mantri, Chun Guang Li, Charlie Xue and Edwin Pang

    Citation: Chinese Medicine 2011 6:18

    Content type: Review

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  10. Eczema is a chronic relapsing atopic dermatitis (AD) associated with pruritus, sleep disturbance and poor quality of life of the patient. Treatment of eczema includes use of emollient, topical and systemic ant...

    Authors: Kam Lun Hon, Ben Chung-Lap Chan and Ping Chung Leung

    Citation: Chinese Medicine 2011 6:17

    Content type: Review

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  11. Ericaulon buergerianum (Gujingcao) is an ophthalmic, anti-inflammatory and antimicrobial Chinese medicinal herb. This study aims to investigate the neuroprotective effects of Ericaulon buergerianum ethanol extrac...

    Authors: Meiwei Wang, Zaijun Zhang, Lorita Chi-Veng Cheang, Zhixiu Lin and Simon Ming-Yuen Lee

    Citation: Chinese Medicine 2011 6:16

    Content type: Research

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  12. Upon initial infection with mycobacteria, macrophages secrete multiple cytokines and chemokines, including interleukin-6 (IL-6), IL-8 and tumor necrosis factor-α (TNF-α), to mediate host immune responses again...

    Authors: Liangjie Wang, Cindy Lai Hung Yang, Terry Cho Tsun Or, Gang Chen, Jian Zhou, James Chun Tsun Li and Allan Sik Yin Lau

    Citation: Chinese Medicine 2011 6:14

    Content type: Research

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  13. Active myofascial trigger points are one of the major peripheral pain generators for regional and generalized musculoskeletal pain conditions. Myofascial trigger points are also the targets for acupuncture and...

    Authors: Hong-You Ge, César Fernández-de-las-Peñas and Shou-Wei Yue

    Citation: Chinese Medicine 2011 6:13

    Content type: Review

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  14. Arctium lappa (Niubang), a Chinese herbal medicine, is used to treat tissue inflammation. This study investigates the effects of arctigenin (AC), isolated from A. lappa, on anti-CD3/CD28 Ab-stimulated cell prolif...

    Authors: Wei-Jern Tsai, Chu-Ting Chang, Guei-Jane Wang, Tzong-Huei Lee, Shwu-Fen Chang, Shao-Chun Lu and Yuh-Chi Kuo

    Citation: Chinese Medicine 2011 6:12

    Content type: Research

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  15. An aqueous extract of multi-hypoglycemic herbs of Panax ginseng C.A.Meyer, Pueraria lobata, Dioscorea batatas Decaisne, Rehmannia glutinosa, Amomum cadamomum Linné, Poncirus fructus and Evodia officinalis was inv...

    Authors: Jiyoung Yeo, Young-Mi Kang, Su-In Cho and Myeong-Ho Jung

    Citation: Chinese Medicine 2011 6:10

    Content type: Research

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  16. EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from isc...

    Authors: Jiangang Shen, Waisin Lee, Yong Gu, Yao Tong, Peter CW Fung and Li Tong

    Citation: Chinese Medicine 2011 6:8

    Content type: Research

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  17. Danshen-Gegen decoction (DG), a Chinese herbal formula, has been demonstrated to be effective for the treatment of coronary heart disease such as myocardial infarction. In the present study, we investigated the e...

    Authors: Sze Man Wong, Po Yee Chiu, Hoi Yan Leung, Limin Zhou, Zhong Zuo, Philip Y Lam and Kam Ming Ko

    Citation: Chinese Medicine 2011 6:7

    Content type: Research

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  18. This article reviews the anti-inflammatory relative and anti-infectious effects of Evodia rutaecarpa and its major bioactive components and the involvement of the nitric oxide synthases, cyclooxygenase, NADPH oxi...

    Authors: Jyh-Fei Liao, Wen-Fei Chiou, Yuh-Chiang Shen, Guei-Jane Wang and Chieh-Fu Chen

    Citation: Chinese Medicine 2011 6:6

    Content type: Review

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  19. Panax notoginseng is an important Chinese medicinal plant. Dammarene-type triterpenoid saponins are main pharmacologically effective compounds in P. notoginseng. This study aims to investigate the formation and a...

    Authors: Dong Wang, Hongtao Zhu, Keke Chen, Min Xu, Yingjun Zhang and Chongren Yang

    Citation: Chinese Medicine 2011 6:5

    Content type: Research

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  20. Panax notoginseng is a potential source of anticancer compounds. This study aims to investigate the effects of steaming on the chemical profile of P. notoginseng and the anti-proliferative effects of P. notoginse...

    Authors: Ding-Fung Toh, Dhavalkumar Narendrabhai Patel, Eric Chun-Yong Chan, Alvin Teo, Soek-Ying Neo and Hwee-Ling Koh

    Citation: Chinese Medicine 2011 6:4

    Content type: Research

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  21. In acupuncture, deqi is the sensory experience related to clinical efficacy. As the first study taking into account cultural differences on deqi sensation, this pilot survey aims to corroborate the acupuncturists...

    Authors: Kathleen KKS Hui, Tara N Sporko, Mark G Vangel, Ming Li, Jiliang Fang and Lixing Lao

    Citation: Chinese Medicine 2011 6:2

    Content type: Research

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  22. Whether pattern similarity causes misdiagnosis and undiagnosis in Chinese medicine is unknown. This study aims to test the effect of pattern similarity and examination methods on diagnostic outcomes of pattern...

    Authors: Arthur Sá Ferreira

    Citation: Chinese Medicine 2011 6:1

    Content type: Research

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  23. One of the biggest obstacles to progress in modern pharmaceutical research is the difficulty of integrating all available research findings into effective therapies for humans. Studies of traditionally used ph...

    Authors: Matthias Samwald, Michel Dumontier, Jun Zhao, Joanne S Luciano, Michael Scott Marshall and Kei Cheung

    Citation: Chinese Medicine 2010 5:43

    Content type: Commentary

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  24. Benefits of engaging community pharmacists in providing wider primary care are internationally acknowledged; in Hong Kong, however, strategies for harnessing their potential contributions are yet to be launche...

    Authors: Vincent Chi Ho Chung, Chun Hong Lau, Frank Wan Kin Chan, Joyce Hoi Sze You, Eliza Lai Yi Wong, Eng Kiong Yeoh and Sian Meryl Griffiths

    Citation: Chinese Medicine 2010 5:41

    Content type: Commentary

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  25. The root of Boehmeria spp (ramie) is a hepatoprotective Chinese herbal medicine. Medicinal properties vary between Boehmeria nivea var. nivea and Boehmeria nivea var. tenacissima, which are local species found in...

    Authors: Chuan-I Li, Shu-Jiau Chiou, Teng-Soung Tong, Cheng-Yu Lee, Lain-Tze Lee and Ching-Ming Cheng

    Citation: Chinese Medicine 2010 5:40

    Content type: Research

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  26. Fructus Ligustri Lucidi (FLL) is a commonly used herb for treating bone disorders in Chinese medicine. The present study investigates the anti-osteoporotic activity of FLL aqueous extract in the model of postmeno...

    Authors: Chun Hay Ko, Wing Sum Siu, Ching Po Lau, ClaraBik San Lau, Kwok Pui Fung and Ping Chung Leung

    Citation: Chinese Medicine 2010 5:39

    Content type: Research

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  27. Radix notoginseng is used in Chinese medicine to improve blood circulation and clotting; however, the pharmacological activities of other parts of Panax notoginseng have yet to be explored. The present study repo...

    Authors: Roy Chi-Yan Choi, Zhiyong Jiang, Heidi Qun Xie, Anna Wing-Han Cheung, David Tai-Wai Lau, Qiang Fu, Tina Tingxia Dong, Jijun Chen, Zhengtao Wang and Karl Wah-Keung Tsim

    Citation: Chinese Medicine 2010 5:38

    Content type: Research

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  28. This article reviews recent basic and clinical studies of ginseng, particularly the anti-cancer effects and the potential chemopreventive actions by activating the transcriptional factor, nuclear factor (eryth...

    Authors: Constance Lay-Lay Saw, Qing Wu and Ah-NgTony Kong

    Citation: Chinese Medicine 2010 5:37

    Content type: Review

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  29. Radix Puerariae is used in Chinese medicine to treat alcohol addiction and intoxication. The present study investigates the effects of Flos puerariae lobatae water extract (FPE) and its active ingredient puerarin...

    Authors: Zaijun Zhang, Sha Li, Jie Jiang, Pei Yu, Jing Liang and Yuqiang Wang

    Citation: Chinese Medicine 2010 5:36

    Content type: Research

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  30. Stroke caused by brain ischemia is the third leading cause of adult disability. Active prevention and early treatment of stroke targeting the causes and risk factors may decrease its incidence, mortality and s...

    Authors: Lihong Zhang, Wai Ping Lam, Lanhai Lü, Chunmei Wang, Yeuk Wa Wong, Lok Hang Lam, Hong Chai Tang, Maria SenMun Wai, Mingwei Wang, Wing Hang Kwong, Sai Ming Ngai, Ying Tat Mak and David TaiWai Yew

    Citation: Chinese Medicine 2010 5:35

    Content type: Research

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  31. Berberine is an active compound in Coptidis Rhizoma (Huanglian) with multiple pharmacological activities including antimicrobial, antiviral, anti-inflammatory, cholesterol-lowering and anticancer effects. The pre...

    Authors: Yibin Feng, Ka-Yu Siu, Xingshen Ye, Ning Wang, Man-Fung Yuen, Chung-Hang Leung, Yao Tong and Seiichi Kobayashi

    Citation: Chinese Medicine 2010 5:33

    Content type: Research

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  32. Many medicinal plants are increasingly endangered due to overexploitation and habitat destruction. To provide reliable references for conservation planning and regional management, this study focuses on large-...

    Authors: Hua Yu, Caixiang Xie, Jingyuan Song, Yingqun Zhou and Shilin Chen

    Citation: Chinese Medicine 2010 5:31

    Content type: Research

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  33. Establishing botanical extracts as globally-accepted polychemical medicines and a new paradigm for disease treatment, requires the development of high-level quality control metrics. Based on comprehensive chem...

    Authors: Robert Tilton, Anthony A Paiva, Jing-Qu Guan, Rajendra Marathe, Zaoli Jiang, Winfried van Eyndhoven, Jeffrey Bjoraker, Zachary Prusoff, Hailong Wang, Shwu-Huey Liu and Yung-Chi Cheng

    Citation: Chinese Medicine 2010 5:30

    Content type: Research

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  34. Radix Polygoni Multiflori is the dried root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae). According to Chinese medicine theory, raw (R-RPM) and processed (P-RPM) Radix Polygoni Multiflori possess dif...

    Authors: Zhitao Liang, Hubiao Chen, Zhiling Yu and Zhongzhen Zhao

    Citation: Chinese Medicine 2010 5:29

    Content type: Research

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  35. Tian Xian Liquid (TXL) is a Chinese medicine decoction and has been used as an anticancer dietary supplement. The present study aims to investigate the effects of TXL on the apoptosis of HT-29 cells and tumor ...

    Authors: Qing Liu, Yao Tong, Stephen ChoWing Sze, Wing Keung Liu, Lam Lam, Ellie ShihngMeir Chu and Christine MiuNgan Yow

    Citation: Chinese Medicine 2010 5:25

    Content type: Research

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  36. Radix Wikstroemiae is a common Chinese herbal medicine. The ethyl acetate fraction of the ethanolic extract of W. indica possesses potent in vitro antiviral activity against respiratory syncytial virus (RSV). Thi...

    Authors: Weihuan Huang, Xiaoli Zhang, Yifei Wang, Wencai Ye, Vincent EC Ooi, Hau Yin Chung and Yaolan Li

    Citation: Chinese Medicine 2010 5:23

    Content type: Research

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