Findings | Model | Treatment | Reference |
---|---|---|---|
DBT had significantly higher RBC and Hb levels in both normal and anemic mice than those in RA, RAS and control. | Kunming mice, male, RBC, Hb | Normal mice in 4 groups: RA, RAS, DBT and control; Anemic mice in 4 groups: RA, RAS, DBT and control | Wu BC et al. [24] |
DBT was the most effective decoction in triggering immune responses. | Kunming mice, RBC, Hb, WBC, Plt, reticulocyte, nucleated cells of bone cavity, weight of pancreas and thymus | Mice in 5 groups: RA, RAS, DBT, RA+RAS (1:1) and control | Li YK et al. [25] |
DBT alleviated cardiac injury in ischemia reperfusion. | Wister rats (male), amplitudes of LVSP and ± dp/dtmax, arterial pressure, Na+-K+-ATP activity, level of MDA production, cAMP content | Rats in myocardial ischemia reperfusion injury; i.v. | Wu DZ et al. [26] |
DBT increased the levels of RBC, WBC, and BMNC. Some DBT promoted the proliferation of BMNC and increased the level of CFU-Mix. | Kunming mice, ICR mice, Balb/c mice, RBC, WBC, reticulocytes and BMNC | Mice in 4 groups: normal, model, DBT without polysaccharides, DBT with polysaccharides | Ning L et al. [27] |
DBT enhanced myocardial mitochondria and red blood cell glutathione status. | Rats, myocardial mitochondrial status, RBC glutathione status | Rats in 5 groups: RA, RAS, DBT, RA + RAS (not boiled together) and control; orally administered | Mak DH et al. [28] |
DBT inhibited growth of GM-CFU, while the decoction-containing serum promoted growth of GM-CFU. | Kunming mice, GM-CFU | DBT was administered orally; serum collected from abdominal aorta was added to an in vitro cultivating system of mouse hematopoietic progenitor cells. | Zhang YH et al. [29] |
The decoction-containing serum showed promoting actions to CFU-E. RA+RAS (5:1) was 97.81% stronger than RA+RAS (1:1). | Kunming mice, CFU-E | DBT was administered orally; serum collected from abdominal aorta was added to an in vitro cultivating system of mouse hematopoietic progenitor cells. | Zhang YH et al. [30] |