Table 1 Fifty percent inhibition concentrations (IC50) and relative resistance of curcumin and cantharidin in sensitive and multidrug-resistant CEM leukemia tumor cell lines [16]
| Â | Curcumin | Cantharidin |
|---|---|---|
Growth inhibition assay: | ||
CCRF-CEM | 30 μM | 20 μM |
CEM/ADR5000 | 28 μM | 17 μM |
Relative resistance | 0.9 | 0.9 |
MTT-Assay: | ||
CCRF-CEM | >13.5 μM | 1.9 μM |
CEM/VBL100 | >13.5 μM | 1.4 μM |
Relative resistance: | n.d. | 1.4 |
CEM/E1000 | 13.5 μM | 0.76 μM |
Relative resistance | n.d. | 0.4 |