Figure 4

LC/MS Chromatograms of PHY906 Extract Stability. Sample stability. Sample and instrument stability were monitored by successive LC/MS(+) profiles of a freshly prepared extract of PHY906-6. Two spectra taken at 0 hours and 18 hours indicate that LC peak positions and peak integrations were stable, samples were visually unchanged with no observed precipitation and peak patterns and intensities did not vary over at least an 18-hour period. The PSI value for the 39 peak pattern between the 0 and 18 hour time points was 0.98. Even minor degradation of the liquid extract was not apparent for at least 24 hours at room temperature.