Figure 5

Effects of EGb761, quecertin and bilobalide on the cleavage activities of caspases in the hypoxia-reoxygenated cardiomyocytes. The extracted proteins from the cardiomyocytes were incubated with Ac-DEVD-AMC and the release of 7-amino-4-methylcoumarin (AMC) was measured. Drug concentrations of EGb761, quecertin and bilobalide were 1, 10 and 100 μg/ml respectively. HO: hypoxia; HR: hypoxia-reoxygenation. Data are shown as mean ± SD (n = 5).