NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements

Table 2 Results of the quantitative ¹H NMR determination of total statins in red yeast rice products

Sample	Sample Labelling	Product origin	Total statins (NMR)		Labelling of monacolin K (mg/capsule)
Sample	Sample Labelling	Product origin	(mg/capsule) ^a	(mg/daily dose) ^b	Labelling of monacolin K (mg/capsule)
S1	Red rice, food supplement, 330 mg capsules (in German)	Austria	1.5 ± 0.1	1.5 - 4.5	1.33
S2	Red yeast rice, food supplement, 600 mg capsules (in English)	USA with UK labelling	3.3 ± 0.4	6.6	no labelling
S3	Red yeast rice, herbal supplement, 330 mg capsules (in English)	UK	5.3 ± 0.6	10.6	no labelling
S4	Red yeast rice, dietary supplement, 600 mg capsules (in English)	USA	6.3 ± 0.2	12.6 - 25.2	no labelling
S5	Red yeast rice, food supplement, 600 mg capsules (in French)	France	8.0 ± 0.6	16.0 - 24.0	9.6

^a Means ± standard deviations (SD) based on 5 replicated measurements (including sample preparation)
^b The daily doses were calculated according to our analytical result and the intake recommendation of the products (a range is given when the manufacturer recommended a range for daily dose)

ISSN: 1749-8546