Table 1 Antiproliferative activity of different jujube seed extracts on non-cancer Vero cell line and T cell leukemic Jurkat cell line evaluated by the NR assay for 24 h incubation
From: Apoptosis-inducing effects of jujube (Zǎo) seed extracts on human Jurkat leukemia T cells
Sample | IC50 (µg/mL) | Selectivity index | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vero cell line | Jurkat cell line | ||||||||||||
Water | Ethanol | Dichloro-methane | Ethyl acetate | Chloroform | Hexane | Water | Ethanol | Dichloro- methane | Ethyl acetate | Chloroform | Hexane | ||
‘Samros’ | Inactive | Inactive | Inactive | nd | nd | nd | Inactive | 417.7 ± 10.4b | Inactive | nd | nd | nd | 1.0 |
‘Bombay’ | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | 487.9 ± 17.5a | Inactive | Inactive | Inactive | Inactive | 1.0 |
‘Apple’ | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | nd |
‘Taiwan’ | Inactive | Inactive | Inactive | Inactive | nd | inactive | Inactive | 232.4 ± 7.8d | Inactive | Inactive | nd | Inactive | 2.1 |
‘Nomsod’ | Inactive | Inactive | Inactive | Inactive | nd | Inactive | Inactive | 333.4 ± 2.8c | Inactive | Inactive | nd | Inactive | 1.0 |
‘Jumbo’ | Inactive | Inactive | Inactive | Inactive | nd | Inactive | Inactive | 312.0 ± 18.3c | Inactive | Inactive | nd | Inactive | 1.6 |
‘Kaew’ | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | Inactive | nd |
‘Rianthong’ | Inactive | Inactive | Inactive | Inactive | nd | Inactive | Inactive | 401.6 ± 9.9b | Inactive | Inactive | nd | Inactive | 1.2 |
Melphalan | 75.0 ± 2.3 | 119.1 ± 10.4e | 0.6 | ||||||||||