Fig. 7

The effect of YQHY on the drug resistance of CD44(-) and CD44(+) (CSCs) cells. A The inhibition rate of CD44(−)BGC823/5-Fu and CD44(+)BGC823/5-Fu treated with YQHY. B The inhibition rate of CD44(-)BGC823/5-Fu and CD44(+)BGC823/5-Fu treated with YQHY + 5-Fu. C The comparison of the inhibition rate of BGC823/5–Fu-CSCs intervened with YQHY or YQHY + 5-Fu. D The apoptosis rate of BGC823/5–Fu-CSCs treated with different concentrations of YQHY or combined with 5-Fu. A–D The duration of administration was 48 h. B–D The concentration of 5-Fu used in CD44(−)BGC823/5-Fu and CD44(+)BGC823/5-Fu was 20 μg/ml and 45 μg/ml, respectively (the IC50 to 5-Fu of each cell line). * represented the comparison between YQHY and Control group; # represented the comparison between YQHY + 5-Fu and 5-Fu group. ^△ represented the comparison between YQHY and YQHY + 5-Fu group