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Table 2 WOMAC and EQ-5D-5L score over time between groups, mean (SD)

From: Therapeutic effect of Duhuo Jisheng Decoction add-on Tui-na manipulation on osteoarthritis of knee: a randomized controlled trial

 

Treatment/control group (baseline)

Difference (95% CI, P value) (baseline)

Treatment/control group (week 2)

Difference (95% CI, P value*) (week 2)

Treatment/control group (week 4)

Difference (95% CI, P value*) (week 4)

Treatment/control group (week 8)

Difference (95% CI, P value*) (week 8)

WOMAC Total score

54.5 (10.8)/57.7 (9.7)

 − 3.2 (− 8.1 to 1.8; 0.20)

41.9 (13.5)

48.3 (13.6)

 − 6.4 (− 12.9 to 0.12; 0.05)

37.0 (16.2)/42.1 (16.3)

 − 5.1 (− 12.9 to 2.7; 0.20)

31.8 (17.3)/39.9 (17.1)

 − 8.2 (− 16.5 to 0.1; 0.05)

Pain subscale

11.9 (2.9)/12.3 (2.9)

 − 0.41 (− 1.8 to 1.0; 0.57)

9.0 (3.1)

10.3 (3.4)

 − 1.2 (− 2.8 to 0.34; 0.12)

7.5 (3.6)/9.0 (3.5)

 − 1.5 (− 3.2 to 0.24; 0.09)

6.8 (3.6)/8.6 (3.6)

 − 1.8 (− 3.5 to − 0.02; 0.048)*

Stiffness subscale

3.9 (1.3)/4.6 (0.9)

 − 0.7 (− 1.3 to − 0.2; 0.013)*

3.0 (1.5)

3.7 (1.4)

 − 0.7 (− 1.4 to − 0.05; 0.035)*

2.8 (1.5)/3.4 (1.4)

 − 0.6 (− 1.3 to 0.08; 0.082)

2.4 (1.4)/3.4 (1.5)

 − 1.0 (− 1.6 to − 0.3; 0.008)*

Physical function subscale

38.7 (7.9)/40.7 (7.1)

 − 2.1 (− 5.7 to 1.6; 0.26)

29.9 (9.9)

34.3 (10.1)

 − 4.4 (− 9.2 to 0.41; 0.07)

26.7 (11.8)/29.7 (12.2)

 − 3.0 (− 8.8 to 2.8; 0.31)

22.6 (12.8)/28.0 (12.6)

 − 5.5 (− 11.6 to 0.65; 0.08)

EQ-5D Index value

0.30 (0.29)/0.19 (0.27)

0.10 (− 0.03 to 0.24; 0.12)

0.47 (0.26)

0.30 (0.33)

0.17 (0.02 to 0.31; 0.022)*

0.51 (0.26)/0.38 (0.34)

0.13 (− 0.01 to 0.28; 0.07)

0.57 (0.30)/0.45 (0.29)

0.11 (− 0.03 to 0.25; 0.13)

EQ VAS

54.7 (16.6)/51.8 (19.1)

3.1 (− 5.5 to 11.7; 0.48)

62.6 (19.3)

59.1 (16.2)

3.5 (− 5.12 to 12.0; 0.42)

65.9 (14.0)/62.1 (18.6)

3.8 (− 4.1 to 11.7; 0.34)

65.7 (19.2)/62.9 (16.5)

2.9 (− 5.8 to 11.5; 0.51)

  1. *Independent T-test