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Fig. 4 | Chinese Medicine

Fig. 4

From: Formononetin alleviates acute pancreatitis by reducing oxidative stress and modulating intestinal barrier

Fig. 4

Formononetin mitigates colonic oxidative stress damage by modulating the Nrf2/Keap1 pathway. A ROS levels in colon of C57BL/6J mice were detected by DHE assay. B ROS levels in the pancreas of C57BL/6J mice were detected by DHE assay. C Network analysis and visualization of ROS-related gene using cytoscape platform. D Analysis of ROS-related gene expression in pancreas of caerulein-induced AP from GEO database. E Western blot detection of Keap1/Nrf2 signaling activation in colon. F Detection of SOD activity in colon. Data were expressed as mean ± SD, n = 3 per group. ** p < 0.01, *** p < 0.001

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