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Fig. 1 | Chinese Medicine

Fig. 1

From: Dual effect of aucubin on promoting VEGFR2 mediated angiogenesis and reducing RANKL-induced bone resorption

Fig. 1

Aucubin improved bone recovery and reduced bone resorption in Col10α1: mGFP/ Rankl:HSE:CFP medaka. A Col10α1: nlGFP expression in 14 dpf transgenic medaka larvae after heat-shock-induced RANKL expression and aucubin (25 and 50 μM) treatments. B ALC staining of the mineralized bone matrix in 14 dpf Col10α1: mGFP/Rankl:HSE:CFP medaka, 5 days after heat-shock-induced RANKL expression and aucubin (25 and 50 μM) treatments. C A merge of A and B. D Fixed bone staining with Alizarin Red in 14 dpf Col10α1: mGFP/Rankl:HSE:CFP medaka larvae after RANKL induction and aucubin (25 and 50 μM) treatments

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