Fig. 6

Aucubin promoted proliferation, migration and tube formation in su5416-injured HUVECs. A Cell viability was measured by CCK8 assays. B The xCELLigence RTCA system showed the data of cell index curves of HUVECs reflected their proliferation in real-time mode. C The healing area of the wound at the time points of 0 h and 12 h were observed microscopically and calculated by Image J software. Effects of aucubin on HUVECs migration was investigated by wound healing. D The migration rate was determined after treatment. E Effects of aucubin on tube formation in su5416-damaged HUVECs was determined. F Graph showing the quantitative analysis of tube length in the control group, su5416 group, and aucubin groups. Data are shown as mean ± SD of at least three independent experiments. ^##P < 0.01 vs. untreated control. *P < 0.05 and **P < 0.01 vs. su5416