Fig. 2

YCF5, the effective fragment of YCF, significantly inhibited M1 macrophage-induced inflammation by suppressing the release of pro-inflammatory factors. A mRNA expression of IL-1β, IL-6, TNF-α, and COX-2 in the different fractions of YCF. B Expression of IL-1β, IL-6, TNF-α, and COX-2 in different concentrations of YCF5. C The total ion chromatogram of YCF5 in negative and positive mode. All data are presented as the mean ± SD (n = 3). ^#p < 0.05, ^##p < 0.01 vs. Control group; ^*p < 0.05, ^**p < 0.01 vs. Model group