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Table 1 Chinese patent medicine with Epimedium as the main medicinal material

From: Effects of genus Epimedium in the treatment of osteoarthritis and relevant signaling pathways

Name

Components

Indication

Drug safety

National drug standard (standard number)

XianLing Gubao capsule

Epimedium, Xu-duan* and other 4 Chinese medicines

Osteoporosis, fractures, OA, aseptic bone necrosis

Receptor X

WS-10269(ZD-0269)-2002-2011Z

Gusongbao capsule

Epimedium, Chi-shao* and other 7 Chinese medicines

Fractures and bone pains caused by osteoporosis

Receptor X

YBZ01612003-2006

Epimedium total flavonoids capsule

Epimedium total flavonoids extraction

Primary osteoporosis with kidney-yang deficiency syndrome

Receptor X

YBZ00132013

Yanghuo Sanqi capsule

Epimedium, San-qi*

Thoracic obstruction caused by yang deficiency and blood stasis

Receptor X

YBZ01792009

Yiqi Bushen capsule

Dang-shen*, Epimedium and other 7 Chinese medicines

Neuroasthenia or climacteric syndrome with spleen and kidney deficiency syndrome

Receptor X

WS-11413(ZD-1413)-2002

Xianlingpi tablet/capsule

Epimedium

Impotence and spermatorrhea, flaccidity of muscule and bone, rheumatic arthralgia

Receptor X

WS-10707(ZD-0707)-2002-2011Z/YBZ23752005-2009Z

Tenghuang Jiangu Pill

Shu-di-huang*, Lu-xian-cao*, Gu-sui-bu*, Rou-cong-rong*, Epimedium and other 2 Chinese medicines

Hypertrophic spondylitis, cervical spondylosis, heel spur, proliferative arthritis, Kashin-Beck disease

Receptor X

WS-11061(ZD-1061)-2002-2012Z

Zhuanggu Guanjie capsule

Shu-di-huang*, Epimedium and other 10 Chinese medicines

Degenerative OA and lumbar muscle strain caused by liver and kidney deficiency, qi stagnation and blood stasis, and meridians obstruction

Receptor X

WS3-709(Z-141)-2010Z

Huoyang Bushen capsule

Ren-shen*, cartialgenous, Epimedium and other 13 Chinese medicines

Syndrome of kidney yang deficiency

Receptor X

WS-5739(B-0739)-2014Z

Hugu capsule

He-shou-wu*, Epimedium and other 8 Chinese medicines

Primary osteoporosis

Receptor X

YBZ12742004-2009Z

Compound Epimedium oral liquid

Epimedium, Shu-di-huang*, and other 6 Chinese medicines

Syndrome of kidney yang deficiency

Over the counter

WS-5357(B-0357) -2002

Huolong Bushen oral liquid

Epimedium, Hai-long* and other 11 Chinese medicines

Syndrome of kidney yang deficiency

Over the counter

WS-5668(B-0668)-2002

Bushen Qiangshen capsule

Epimedium, Jin-ying-zi* and other 3 Chinese medicines

Kidney deficiency syndrome

Over the counter

WS3-B-0751–91

Yinyangsuo capsule/granule

Epimedium, Wu-wei-zi*

Impotence and premature ejaculation in male disease

Receptor X

YBZ01852008/YBZ24472005

  1. *Are the pin-yin names of the medicinal materials, and their corresponding Latin names are as follows: Xu-duan, Dipsacus asper Wall. ex DC.; Chi-shao, Paeonia anomala subsp. veitchii (Lynch) D.Y.Hong & K.Y.Pan; San-qi, Panax notoginseng (Burkill) F.H.Chen ex C.Y.Wu & K.M.Feng; Dang-shen, Codonopsis pilosula (Franch.) Nannf. or Codonopsis pilosula subsp. Pilosula or Codonopsis pilosula subsp. tangshen (Oliv.) D.Y.Hong; Shu-di-huang, Rehmannia glutinosa (Gaertn.) DC.; Lu-xian-cao, Pyrola calliantha Andres or Pyrola decorata Andres; Gu-sui-bu, Drynaria roosii Nakaike; Rou-cong-rong, Cistanche deserticola Ma or Cistanche phelypaea (L.) Cout.; Ren-shen, Panax ginseng C.A.Mey.; He-shou-wu, Reynoutria multiflora (Thunb.) Moldenke; Hai-long, Solenognathus hardwicki (Gray) or Syngnathoides biaculeatus (Bloth) or Syngnathus acus Linnaeus; Jin-ying-zi, Rosa laevigata Michx.; Wu-wei-zi, Schisandra chinensis (Turcz.) Baill. or Schisandra sphenanthera Rehder & E.H.Wilson