Fig. 2

Cynomolgus monkey skin cell clusters defined by scRNA-seq. A Overview of the scRNA-seq experiment. SBM and vehicle solution were smeared twice daily for 12 days, and scRNA-seq was performed for the skin smeared of the same cynomolgus monkey with SBM and vehicle solution. B Uniform Manifold Approximation and Projection (UMAP) plot for dimension reduction of two paired samples cells colored by their cell type/identity. C Featureplot plots showing marker gene expression for cell type identification. Legend shows a color gradient of normalized expression. D Dotmap of top 5 differentially expressed genes (DEGs) across cell clusters. Red represents high expression; blue represents low expression