Fig. 12
Integration analysis of “metabolites-genes-pathways” regulated by BGZ in rats with Yinsyn and Yangsyn. A–B Venn analysis of the crosstalk pathways of co-regulation of metabolites and DEGs by BGZ in Yinsyn (A) and Yangsyn (B) rats, C–D Visualization of the network relationship among the “metabolite-gene-pathway” regulated by BGZ in rats with Yinsyn (C)and Yangsyn (D). E–F Effect of BGZ treatment on the changes in the expression of Na+-K+-ATPase (E) and LDH (F) (N = 6 ~ 8). *P < 0.05, **P < 0.01, compared with CON group; #P < 0.05, compared with Yangsyn group; &P < 0.05, compared with Yinsyn group