Table 1 Identified differential metabolites
ESI | m/z | RT (min) | KEGG | Metabolite | (Yangsyn+BGZ) vs. (Yangsyn) | (Yinsyn+BGZ) vs. (Yinsyn) |
|---|---|---|---|---|---|---|
− | 145.0132 | 0.9378 | C00026 | α-Ketoglutarate | ↑* | ↓ |
− | 455.0965 | 2.9226 | C00061 | Riboflavin-5-phosphate | ↑* | ↓* |
− | 104.0348 | 0.8028 | C00065 | L-Serine | ↑ | ↓* |
+ | 113.0352 | 0.9136 | C00106 | Uracil | ↓* | ↑* |
+ | 778.5407 | 13.2262 | C00157 | Phosphatidylcholine | ↑ | ↓ |
− | 582.5100 | 13.2602 | C00195 | N-Acylsphingosine | ↑** | ↓* |
− | 148.0378 | 1.3859 | C00250 | Pyridoxal | ↑* | ↓* |
− | 243.0615 | 1.3509 | C00299 | Uridine | ↓ | ↑* |
− | 102.0556 | 0.8313 | C00334 | gamma-Aminobutyric acid | ↑* | ↓* |
− | 766.6037 | 9.3765 | C00350 | Phosphatidylethanolamine | ↓** | ↑* |
− | 240.0224 | 1.5073 | C00352 | Glucosamine 6-phosphate | ↑* | ↓** |
− | 151.0569 | 0.9235 | C00379 | D-Xylitol | ↑ | ↓* |
− | 671.4653 | 13.3460 | C00416 | Phosphatidate | ↓*** | ↑* |
+ | 173.0922 | 0.8994 | C00430 | 5-Aminolevulinate | ↓** | ↑ |
+ | 160.0756 | 1.9497 | C00483 | Tyramine | ↓* | ↑* |
− | 583.2469 | 8.6720 | C00486 | Bilirubin | ↑ | ↓* |
+ | 583.2554 | 8.0917 | C00500 | Biliverdin | ↑** | ↓* |
+ | 90.0555 | 0.8565 | C00546 | Methylglyoxal | ↑ | ↓* |
− | 397.2291 | 11.6884 | C00584 | Prostaglandin E2 | ↓** | ↑* |
− | 229.0667 | 1.6209 | C00588 | Phosphorylcholine | ↑* | ↓* |
+ | 426.3162 | 15.2409 | C00695 | Cholic acid | ↑ | ↓** |
+ | 252.0724 | 2.1330 | C00818 | Glucaric acid | ↑ | ↓* |
+ | 465.3556 | 11.5639 | C01724 | Lanosterin | ↑ | ↓* |
+ | 799.6627 | 15.2528 | C01829 | Thyroxine | ↑** | ↓ |
+ | 196.0943 | 4.0050 | C03264 | D-Leucate | ↑** | ↓ |
− | 187.1076 | 1.3080 | C02727 | N6-Acetyl-L-lysine | ↑* | ↓* |
+ | 560.3333 | 8.4013 | C03033 | beta-D-Glucuronoside | ↑* | ↓ |
− | 205.0645 | 1.7274 | C03227 | 3-Hydroxy-L-kynurenine | ↓* | ↑* |
+ | 522.3564 | 9.5634 | C04230 | 1-Acyl-sn-glycero-3-phosphocholine | ↑** | ↓ |
− | 401.0785 | 6.4160 | C04352 | (R)-4’-Phosphopantothenoyl-L-cysteine | ↑** | ↓*** |
+ | 381.0794 | 0.9636 | C04778 | N1-(5-Phospho-a-D-ribosyl)-5,6-dimethylbenzimidazole | ↓* | ↑** |
− | 347.1835 | 8.9063 | C05302 | 2-Methoxyestradiol | ↑ | ↓** |
− | 526.0585 | 1.3859 | C05381 | 3-Carboxy-1-hydroxypropylthiamine diphosphate | ↓ | ↑* |
+ | 389.2142 | 4.7813 | C05476 | Tetrahydrocorticosterone | ↑** | ↓ |
− | 183.0346 | 0.8099 | C05580 | 3,4-Dihydroxymandelate | ↓ | ↑* |
− | 297.0703 | 0.9593 | C05648 | 5-Hydroxy-N-formylkynurenine | ↑ | ↓* |
− | 577.3444 | 13.7089 | C05789 | L-Urobilinogen | ↓* | ↑ |
− | 365.2324 | 6.4089 | C14777 | 12(S)-HETE | ↓* | ↑* |
+ | 353.2472 | 6.4221 | C16513 | Docosapentaenoic acid (22n-3) | ↑* | ↓* |
+ | 136.0396 | 1.6256 | C22040 | Methylcysteine | ↑* | ↓** |