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Fig. 12 | Chinese Medicine

Fig. 12

From: Jian Yun Qing Hua Decoction inhibits malignant behaviors of gastric carcinoma cells via COL12A1 mediated ferroptosis signal pathway

Fig. 12

JYQHD inhibits xenograft tumor growth via COL12A1-mediated ferroptosis in GC cells. A JYQHD suppressed in-vivo xenograft tumor growth, while COL12A1 over-expression counteracted the anticancer effect of JYQHD. The distinction of tumors was shown in the representative photograph through tumor xenograft assay. B, C The differences in weight and volume of subcutaneous tumors were determined and compared between oe-NC, JYQHD and JYQHD + oe-COL12A1 groups at 19th day. D IHC analyzed the expression of COL12A1, GPX4 and SLC7A11 protein of tumors from the oe-NC, JYQHD and JYQHD + oe-COL12A1 cells groups. **P < 0.01 JYQHD group vs the control group. ##P < 0.01 JYQHD + oe-COL12A1 group vs JYQHD group. Scale bar = 50 μm (D)

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Chinese Medicine

ISSN: 1749-8546

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