Fig. 3
JYQHD promotes GC cell ferroptosis. A–E JYQHD-medicated serum induced the ferroptosis of GC cells. Ferroptosis was evaluated by detecting Fe2+, MDA, GSH and ROS levels. This work acquired confocal laser scanning microscope images for ROS production. (F) JYQHD-medicated serum promoted the mitochondrial membrane density increased (black arrow) and the mitochondrial ridge shrank or disappeared (white arrow) in the ferroptosis process of MKN-45 and SGC-7901 cells. This work acquired TEM images showing mitochondrial morphology. **P < 0.01 JYQHD group vs the control group. Scale bar = 400 μm (E). Scale bar = 1 μm (F)