Fig. 9
COL12A1 promotes GC cell growth in vivo. A Knockdown of COL12A1 suppressed in-vivo xenograft tumor growth. Tumor distinction was shown in the representative photograph through tumor xenograft assay. B, C The differences in weight and volume of subcutaneous tumors were determined and compared between sh-COL12A1 and sh-NC cells groups. D IHC analyzed the expression of COL12A1, GPX4 and SLC7A11 protein of tumors from the sh-NC and sh-COL12A1 groups. **P < 0.01 sh-COL12A1 group vs the control group. Scale bar = 50 μm (D)